Results 71 to 80 of about 1,833,102 (295)

Phase Separation of TRIM21 Modulates PTPN14 Stability to Drive Flow‐Dependent Endothelial Activation and Atherogenesis

open access: yesAdvanced Science, EarlyView.
Disturbed flow promotes the formation of TRIM21‐rich biomolecular droplets, which concentrate TRIM21 and PTPN14 and facilitate their SPRY‐FERM interaction (illustrated by the TRIM21 D355‐PTPN14 R132 salt bridge). This condensate‐driven proximity enables TRIM21 to catalyze K48‐linked polyubiquitination of PTPN14 at lysine 956, leading to proteasome ...
Xue He   +10 more
wiley   +1 more source

Pregnancy outcome during haemodialysis: a case report [PDF]

open access: yes, 2009
Objective: Successful pregnancy outcome is an uncommon occurrence in women requiring chronic dialysis treatment. Methods: We reported the course and outcome of a case of pregnancy occurred in a woman affected by lupus erythematosus on chronic ...
Cosimo, Caterina, Franco, Ciro
core   +1 more source

Analysis of Pregnancy, Labor and Perinatal Outcomes of Women with Syphilis

open access: yesМедицинский вестник Юга России, 2011
Purpose: To estimate the influence of infection with syphilis during pregnancy, birth and state of the newborn.Materials and Methods: surveyed 51 pregnant women with syphilis (study group).
A. N. Rymashevsky   +3 more
doaj  

Vertical Transmission of HIV-1 in the Metropolitan Area of Belo Horizonte, Brazil: 2006-2014 [PDF]

open access: yesRevista Brasileira de Ginecologia e Obstetrícia, 2018
Objective To revise HIV-1 vertical transmission (VT) rates in the metropolitan area of Belo Horizonte, Brazil, from January of 2006 to December of 2014.
Victor Hugo Melo   +9 more
doaj   +2 more sources

Challenges of a Pregnancy Gone Wrong: Pregnancy Complications, Illness Perceptions and Distress [PDF]

open access: yes, 2014
Women with pregnancy complications need to cope with a pregnancy that can have life changing consequences. The objective of this research project was to understand the experience of women who had been diagnosed with a pregnancy complication. The research
Currie, Jane Christina Helen
core  

NSUN2‐Mediated m5C Modification of TGFB1 in Trophoblasts Remodels Macrophage Function to Prevent URSA

open access: yesAdvanced Science, EarlyView.
NSUN2 and m5C decline in URSA villous tissues. Trophoblast Nsun2 ablation disrupts macrophage‐mediated maternal‐fetal tolerance and triggers embryo resorption. Mechanistically, NSUN2‐YBX1 axis stabilizes m5C‐modified TGFB1 mRNA to maintain TGF‐β1 secretion and M2 polarization, and restoring this signaling rescues maternal‐fetal immune tolerance to ...
Xiaoxiao Zhu   +10 more
wiley   +1 more source

Influence of SARS-CoV-2 variants of concern and maternal vaccination status on neonatal outcome

open access: yesBMJ Paediatrics Open
SARS-CoV-2 infection during pregnancy can adversely affect maternal and neonatal health, although risks vary depending on the variant of concern (VOC). Omicron, although highly infectious, causes fewer maternal and neonatal complications than earlier VOC,
Rolf Felix Maier   +4 more
doaj   +1 more source

Gut Microbiota‐Derived Indole‐3‐Propionic Acid Alleviates Diabetic Osteoporosis Through Nrf2‐Mediated Ferroptosis Suppression

open access: yesAdvanced Science, EarlyView.
Diabetes‐associated dysbiosis is accompanied by reduced Clostridium abundance, impaired microbial tryptophan metabolism, and lower circulating indole‐3‐propionic acid (IPA). Exogenous IPA improves trabecular microarchitecture and bone formation and restores Nrf2‐associated antioxidant signaling in bone marrow mesenchymal stem cells, limiting iron ...
Jinwu Bai   +12 more
wiley   +1 more source

Rational use of antimicrobials in obstetric practice in view of growing antibiotic resistance

open access: yesЛечащий Врач
Background. Urogenital infections are a leading risk factor for isthmic-cervical insufficiency and preterm labor, and the main role in most cases is played by representatives of opportunistic microflora.
A. Z. Khashukoeva   +5 more
doaj   +1 more source

Study protocol: differential effects of diet and physical activity based interventions in pregnancy on maternal and fetal outcomes--individual patient data (IPD) meta-analysis and health economic evaluation. [PDF]

open access: yes, 2014
© 2014 Ruifrok et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and ...
Kerry, S.   +263 more
core   +2 more sources

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