Advanced Science, EarlyView.G9a, and DNA Methyltransferase1 (DNMT1) cooperatively modulates E2F1 on the promoter of tumor suppressor p53‐binding protein 2 (TP53BP2) increased autophagy in preeclampsia. TP53BP2 promotes autophagy in trophoblasts through DNA methylation and H3K9me2‐mediated transcriptional regulation.
Nan Jiang +12 more
wiley +1 more source
Complications in adolescent pregnancy: systematic review of the literature
Einstein (São Paulo)Sexual activity during adolescence can lead to unwanted pregnancy, which in turn can result in serious maternal and fetal complications. The present study aimed to evaluate the complications related to adolescent pregnancy, through a systematic review ...
Walter Fernandes de Azevedo +4 more
doaj +1 more source
Mode of first delivery and severe maternal complications in the subsequent pregnancy [PDF]
, 2017 Lotte Berdiin Colmorn +11 more
openalex +1 more source
Advanced Science, EarlyView.In trophoblast cells, T/S (TNFα + SM164) activated caspase‐3, which cleaved GSDME to switch apoptosis to pyroptosis, causing cell swelling, membrane rupture, and release of LDH, HMGB1, IL‐1β and IL‐18. These cytokines induced pro‐inflammatory macrophage polarization, which in turn reinforced pyroptotic signaling in trophoblasts, amplifying systemic ...
Baoying Huang +15 more
wiley +1 more source
A Case Series on Pregnant Patients with Ovarian Cysts and Management of Potential Complications
Indonesian Journal of Obstetrics and Gynecology(English) Objective: To report a series of ovarian cyst cases in pregnancy that we diagnosed in our obstetrics and gynecology department; and to provide literary perspective in management of potential complications.
Gezta Nasafir Hermawan +1 more
doaj +1 more source
Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders
Advanced Science, EarlyView.Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li +7 more
wiley +1 more source
Diabetes Mellitus in Pregnancy and Obstetrics Outcome [PDF]
, 2012 Diabetes mellitus in pregnancy was associated with maternal and neonatal mortality and morbidity. This paper was purposed to assess the several cases of diabetes mellitus in pregnancy that were managed in Zainoel Abidin Hospital, Banda Aceh.
Febia, E. (Eva), Rajuddin, R. (Rajuddin)
core
A Counselling Intervention for Individual Strategies to Prevent Complications and Strengthen Resources during Pregnancy in the Gynaecological Care (AOK-Family+): Study Protocol for a Cluster-Randomised Controlled Trial [PDF]
, 2023 Mareike Krämer +6 more
openalex +1 more source
Migrasomes in Ischemic Stroke: Molecular Landscape and Pathophysiological Impact
Advanced Science, EarlyView.Multi‐omics profiling of stroke patients exposes systemic molecular fingerprints of immune activation, oxidative stress and metabolic collapse. Complement and coagulation cascade, and cholesterol metabolism emerge as shared functional hallmarks of plasma migrasomes in stroke patients and migrasomes isolated from experimental stroke mice.
Huifen Zhou +16 more
wiley +1 more source
Urinary Tract Infections in Pregnancy - Diagnosis, Treatment and Prevention [PDF]
, 2012 Objectives: Literature review of classification, epidemiology, pathophysiology, microbiology, clinical presentation, diagnosis, complications, treatment and prevention of urinary tract infections (UTI) in pregnancy.
Campos, A, Figueiredo, A, Gomes, G
core