Results 281 to 290 of about 572,077 (339)

Impact of Inherited Thrombophilia on Pregnancy Complications and the Role of Low-Molecular-Weight Heparin Therapy: A Case-Control Study. [PDF]

Medicina (Kaunas)
Maglic D, Mandic-Markovic V, Mikovic Z, Maglic R, Anicic R, Mandic M.   +5 more
europepmc   +1 more source

Intravenous lanadelumab for the treatment of moderately ill COVID‐19 patients

British Journal of Clinical Pharmacology, EarlyView.
Aims Kallikrein‐kinin system (KKS) dysregulation is hypothesized to play a pathogenetic role in COVID‐19‐associated pulmonary oedema. To investigate the efficacy and safety of intravenous lanadelumab, a monoclonal antibody that inhibits plasma kallikrein, in COVID‐19, we conducted a phase 2, open‐label, randomized‐controlled, proof‐of‐concept ...
Job J. Engel, Christine van Linge, W. Joost Wiersinga, Ilse J. E. Kouijzer, Quirijn de Mast, Robert‐Jan Hassing, Danique J. H. Huijbens, Helen L. Leavis, Roger Schutgens, Coen Maas, Kit C. B. Roes, Frank L. van de Veerdonk, Roger Brüggemann   +12 more
wiley   +1 more source

Tacrolimus exposure during pregnancy in kidney and liver transplantation recipients: A comparison between whole blood and plasma concentration‐to‐dose ratios

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Tacrolimus monitoring is generally performed in whole blood (WB). Most (>85%) of circulating tacrolimus is bound to red blood cells. During pregnancy, WB monitoring might be suboptimal because of physiological changes including increased plasma volume and decreased haematocrit.
Jildau R. Meinderts, Paola Mian, Frederike G. I. van Vilsteren, Karien M. H. van de Wetering, Jelmer R. Prins, Stefan P. Berger, Daan J. Touw, Margriet F. C. de Jong   +7 more
wiley   +1 more source

Pregnancy Complications and Outcomes in Obese Women with Gestational Diabetes. [PDF]

Medicina (Kaunas)
Ramonienė G, Malakauskienė L, Savukynė E, Maleckienė L, Gruzdaitė G.   +4 more
europepmc   +1 more source

Long‐term impact of Elexacaftor/Tezacaftor/ivacaftor on pulmonary, nutritional and metabolic outcomes in homozygous F508del cystic fibrosis patients: A real‐world cohort study

British Journal of Clinical Pharmacology, EarlyView.
Aim Elexacaftor/tezacaftor/ivacaftor (ETI) has markedly improved cystic fibrosis (CF) outcomes. However, its long‐term impact on nutrition, metabolism and liver health remains underexplored. We assessed 30‐month changes in pulmonary, nutritional, metabolic and inflammatory markers in people with CF (PwCF) homozygous for F508del.
Nicola Perrotta, Luigi Angelo Fiorito, Roberta Vescovo, Anna Virgilio, Giulia Amato, Giuseppe Cimino   +5 more
wiley   +1 more source

Exercise Intervention to Mitigate the Cardiovascular Sequence of Pregnancy Complications. [PDF]

Cureus
Rawat A, Vyas K.
europepmc   +1 more source

Failing maternal-fetal tolerance in SLE (FaMaLE): a prospective cohort study for finding the molecular mechanisms behind pregnancy complications. [PDF]

Lupus Sci Med
Dankers W, van Ruitenbeek JF, Germe SA, Parra Sánchez AR, van Gaal MFHM, Hortensius M, Cramer K, Rohrich-Heldens DC, de Boer M, van Baarsen LGM, Bultink IEM.   +10 more
europepmc   +1 more source

Pregnancy Complications and Long-Term Atherosclerotic Cardiovascular Disease Risk. [PDF]

Curr Atheroscler Rep
Rabadia SV, Heimberger S, Cameron NA, Shahandeh N.   +3 more
europepmc   +1 more source