The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Factor V Leiden mutation and pregnancy. Haemostasis during pregnancy in non-carriers and carriers of factor V Leiden mutation, with special emphasis on placenta-mediated and venous thromboembolic complications and on blood coagulation and fibrinolysis markers for prediction of complications [PDF]
Factor V Leiden (FVL) mutation elevates the risk of venous thromboembolism (VTE) in general. During pregnancy, the haemostatic balance is changed in the direction of hypercoagulability, resulting in an increased incidence of VTE. 42 women were followed
Kjellberg, Ulla
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Pyelonephritis in Pregnancy: Clinical and Laboratorial Aspects and Perinatal Results [PDF]
Objective To identify the prevalence of pyelonephritis during pregnancy and to analyze the clinical and laboratorial aspects, perinatal results and complications.
Djulie Anne de Lemos Zanatta +2 more
doaj +2 more sources
Background: Adolescent pregnancy is a pregnancy that occurred between the age of 10-19 years. The survey in 2019 in Indonesia showed that the number of pregnant women aged 15-19 years reached 47 per 100 pregnancies.
Shifa Muthia Shani +2 more
doaj +1 more source
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
Mixed methods research of crisis pregnancy counselling and support services [PDF]
This study aimed to examine women’s experiences of crisis pregnancy counselling using both qualitative and quantitative methods. The study group comprised women with a crisis pregnancy who either decided on abortion or were continuing the pregnancy ...
Conlon, Catherine
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ABSTRACT Background Collaterals are crucial factors that influence the infarct growth rate (IGR). We aimed to determine whether a comprehensive multimodal collateral score (MCS), incorporating collateral assessment at the arterial, tissue, and venous levels, is associated with functional independence and provides incremental prognostic value over ...
Giorgio Busto +12 more
wiley +1 more source
Management of psoriasis in pregnancy – a review of the evidence to date
The onset of psoriasis collides with women’s reproductive timeframe, and pregnancy brings challenges to its treatment. Indeed, the health of both mother and foetus must be considered.
Clara Ferreira +3 more
doaj +1 more source
Irish contraception and crisis pregnancy [ICCP] study: a survey of the general population - summary [PDF]
The aim of the present study was to establish nationally representative data on current attitudes, knowledge and experience of contraception, crisis pregnancy and related services in Ireland.
McGee, Hannah +3 more
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