Results 51 to 60 of about 1,753,767 (304)

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Comprehensive Assessment of Arterial, Tissue, and Venous Collaterals for Evaluating the Infarct Growth Rate: The Multimodal Collateral Score

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Collaterals are crucial factors that influence the infarct growth rate (IGR). We aimed to determine whether a comprehensive multimodal collateral score (MCS), incorporating collateral assessment at the arterial, tissue, and venous levels, is associated with functional independence and provides incremental prognostic value over ...
Giorgio Busto, Umberto Pensato, Ilaria Casetta, Giorgio U. Marcello, Angelo Barra, Anna Poggesi, Edoardo Carlesi, Sara Mancini, Andrea Ginestroni, Vittorio Miele, Alessandro Padovani, Andrea Morotti, Enrico Fainardi   +12 more
wiley   +1 more source

Management of psoriasis in pregnancy – a review of the evidence to date

Drugs in Context, 2020
The onset of psoriasis collides with women’s reproductive timeframe, and pregnancy brings challenges to its treatment. Indeed, the health of both mother and foetus must be considered.
Clara Ferreira, Alexandra Azevedo, Miguel Nogueira, Tiago Torres   +3 more
doaj   +1 more source

Complications of Pregnancy [PDF]

, 2019
Complications of pregnancy are health issues that are caused by pregnancy itself. These can happen during or after delivery (obstetric labor complications or puerperal disorders).

core   +1 more source

Second-generation antipsychotics and pregnancy complications [PDF]

, 2020
Purpose To study if second-generation antipsychotic (S-GA) use during pregnancy is associated with an increased risk of pregnancy and neonatal complications.
Lahesmaa-Korpinen, A-M, Leinonen, Maarit K., Saastamoinen, L, Lahesmaa-Korpinen, Anna-Maria, Malm, Heli, Gissler, M,, Leinonen, MK, Elfolk, M, Nurminen, Marja-Leena, Malm, H, Saastamoinen, Leena, Nurminen, M-L, Gissler, Mika, Ellfolk, Maria   +13 more
core   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

Abdominal pregnancy discovered during laparotomy for complications after attempted abortion [PDF]

, 2016
We report a case of abdominal pregnancy with a dead foetus of 19 gestational weeks and 3 days discovered incidentally during a laparotomy following complications of attempted abortion.
Madoue, Gabkika Bray, Hissein Adenao Mahamat, Anicet, Zapayeke, Zapayeke Anice, Mahamat, Hissein Adenao, Gabkika Bray Madoue, Salathiel, Djongali Tchonchimbo, Pierre, Mahamat, Djongali Tchonchimbo Salathiel, Mahamat Pierre   +9 more
core   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

Factors influencing maternal health complications during pregnancy and immediate postpartum periods in Bangladesh

Discover Public Health
Background The majority of maternal deaths occurs due to health complications during pregnancy and immediate postpartum period. Despite notable progress, Bangladesh remains far from achieving the Sustainable Development Goal 3 target to reduce maternal ...
Shahnaz Nilima, Md. Shahjahan Kabir, Fatima Tuz Zahura   +2 more
doaj   +1 more source

UTERINE MALFORMATIONS AND PREGNANCY COMPLICATIONS

Arta Medica, 2020
Summary The incidence of congenital uterine malformations is 3-5%. Often they lead to reproductive loss and other complications of pregnancy. The correct and timely diagnosis and surgical correction of abnormalities of the Müllerian duct is one of the
Nadejda Codreanu, Daniela Andries
doaj