Results 111 to 120 of about 64,887 (307)

Beyond the label: Rethinking off‐label drug use in paediatrics. Towards a scientifically grounded and safer future for paediatric pharmacotherapy

British Journal of Clinical Pharmacology, EarlyView.
Abstract Despite regulatory progress being made in the past two decades, off‐label drug use in paediatrics remains pervasive, with prevalence estimated between 3% and 97% of prescriptions across different clinical settings. Off‐label use—defined as prescribing outside the conditions described in the Summary of Product Characteristics (SmPC)—is often ...
Tjitske M. van der Zanden, Miriam G. Mooij, Matthijs de Hoog, Saskia N. de Wildt   +3 more
wiley   +1 more source

Molar pregnancy in adolescents.

The Journal of reproductive medicine, 2012
To describe the clinical presentation of hydatidiform molar pregnancy in women under the age of 20 years. In addition, we sought to understand if this adolescent population manifests differences in clinical factors compared to an adult population that may affect outcome.We used a database from the New England Trophoblastic Disease Center to analyze ...
Braga, Antônio, Growdon, Whitfield B., Bernstein, Marilyn, Maestá, Izildinha, Rudge, Marilza Vieira Cunha, Goldstein, Donald P., Berkowitz, Ross S.   +6 more
openaire   +2 more sources

Socio-Economic Determinants Of Abortion Rates [PDF]

Abortion rates are increasing all around the world, especially for young women. Our proposals for public policies to reduce unwanted pregnancies are based on an analysis of the socio-economic determinants of abortion rates.
Gil-Lacruz, Ana Isabel, Bernal Cuenca, Estrella, Gil Lacruz, Marta   +2 more
core  

Zuranolone: A case study in (regulatory) rush to judgement?

British Journal of Clinical Pharmacology, EarlyView.
Abstract Sage, in collaboration with Biogen, submitted a new drug approval for zuranolone for postpartum depression (PPD) and major depressive disorder (MDD) in December 2022. In August 2023, the US Food and Drug Administration granted approval for PPD but denied approval for MDD.
Lisa Cosgrove, Milutin Kostic, Barbara Mintzes, Gianna D'Ambrozio, Allen Shaughnessy   +4 more
wiley   +1 more source

Family approach to pregnancy in adolescence

Acta Médica del Centro, 2011
A descriptive longitudinal study aimed at characterizing pregnant adolescents, from a family perspective, was carried out at the Ramón Pando Ferrer Teaching Polyclinic in Santa Clara , Villa Clara province, during the period from April 2008 to March 2009.
Carlos Alberto León Martínez, Rafaela Mayelín Espín Coto, Yadamila García Cedeño   +2 more
doaj  

What is and how can be explained pregnancy in adolescence

, 2014
ResumoIntrodução: O exercício da sexualidade de forma inconsequente pode gerar inúmeros conflitos e interferir nos planos futuros de cada adolescente, resultando em gravidez precoce, por exemplo.
Valenti, Vitor Engrácia, Queiroga, Kallyne Rubyan Oliveira, Abrantes, Kennia Sibelly Marques de, Farias, Maria do Carmo Andrade Duarte de, Nascimento, Aissa Romina Silva do, Abreu, Luiz Carlos de, Casimiro, Geofabio Sucupira, Maia, Paula Christianne Gomes Gouveia Souto   +7 more
core   +1 more source

Contraindicated drug–drug interactions and associated adverse drug reactions in an observational cohort study of 4543 paediatric hospitalized patients

British Journal of Clinical Pharmacology, EarlyView.
Abstract Background and Purpose Drug–drug interactions (DDIs) are associated with an increased risk of adverse drug reactions (ADRs). Hospitalized children are particularly vulnerable to DDIs and ADRs due to polypharmacy, frequent use of unlicensed or off‐label medications, and dosing regimens often extrapolated from adult data.
Emilie Laval, Sylvain Goutelle, Inesse Boussaha, Xavier Dode, Yanis Mimouni, Kim An Nguyen, Behrouz Kassai   +6 more
wiley   +1 more source

Comportamiento de los niveles sericos de zinc durante el embarazo

Archivos Latinoamericanos de Nutrición
El zinc interviene en el crecimiento y desarrollo, siendo de especial importancia en la gestación. A fin de determinar el comportamiento de los niveles séricos de zinc durante el embarazo asociándolo al estado nutricional antropométrico y consumo ...
Nelina Ruíz F, Lesbia Meertens de R, Evelyn Peña, Armando Sánchez, Liseti Solano   +4 more
doaj  

Risk factors associated with pregnancy in adolescents

Revista Información Científica, 2017
A case-control study was carried out to identify risk factors for pregnancy in adolescence in the polyclinic "Emilio Daudinot in 2013. The universe: pregnant teenagers captured during that year (42 cases) and the double of adolescents who never were ...
Niurka Rodríguez Rodríguez, Ángela Cala Bayeux, Jorge Luis Nápoles Pérez, Yeiner Milán Arenado, Merkis Aguilar Tito   +4 more
doaj  

Abusive Romantic Relationships among Adolescent and Young Adult Mothers [PDF]

The associations between intimate partner violence (IPV) and mental health among adolescents and young adults were compared in the current study. The connections among marriage status, Latino heritage and abusive experiences were also analyzed. 672 women
Suzanne Leaman, Christina B. Gee
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