Results 141 to 150 of about 114,859,711 (330)
British Journal of Clinical Pharmacology, EarlyView.Abstract Despite regulatory progress being made in the past two decades, off‐label drug use in paediatrics remains pervasive, with prevalence estimated between 3% and 97% of prescriptions across different clinical settings. Off‐label use—defined as prescribing outside the conditions described in the Summary of Product Characteristics (SmPC)—is often ...
Tjitske M. van der Zanden +3 more
wiley +1 more source
Zuranolone: A case study in (regulatory) rush to judgement?
British Journal of Clinical Pharmacology, EarlyView.Abstract Sage, in collaboration with Biogen, submitted a new drug approval for zuranolone for postpartum depression (PPD) and major depressive disorder (MDD) in December 2022. In August 2023, the US Food and Drug Administration granted approval for PPD but denied approval for MDD.
Lisa Cosgrove +4 more
wiley +1 more source
O consumo alimentar de gestantes adolescentes no Município do Rio de Janeiro
Cadernos de Saúde PúblicaO crescimento da gravidez na adolescência é visto com preocupação pela área de saúde pública. O consumo de alimentos que atendam a alta demanda de nutrientes durante a gestação tem sido identificado como um componente relevante.
Denise Cavalcante de Barros +3 more
doaj
A study of sexual health issues attitudes and behaviours: The view of early school leavers [PDF]
, 2004 A core objective of this study was the systematic investigation of the sexual attitudes, beliefs and behaviours of early school leavers. The study also aimed to explore the process and mechanisms whereby young people construct, experience and define ...
Byrne, Tina, Mayock, Paula
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British Journal of Clinical Pharmacology, EarlyView.Aims This study aimed to improve the understanding of lithium's safety profile by analysing the frequency and distribution of reported adverse drug reactions (ADRs) compared to second‐generation antipsychotics (SGAs). Methods Individual case safety reports from VigiBase (1968–October 2023) involving individuals older than 2 years, with lithium or SGAs ...
Lisa T. Ringeling +8 more
wiley +1 more source
Termination of Pregnancy Prescribed Information Reporting Requirements
, 2017 Section 17 of the Termination of Pregnancy Law Reform Act requires medical practitioners who perform or direct the performance of a termination of pregnancy to provide to the Chief Health Officer with prescribed information within the timeframe ...
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British Journal of Clinical Pharmacology, EarlyView.Aims This study aimed to analyse clinical investigation‐device initial submissions received by the MHRA between January 2022 and December 2025. Methods Data on submissions were extracted from the clinical investigations unit data bank; software as medical devices were not included. The predefined primary end‐point was submission type.
Andrea Manfrin +7 more
wiley +1 more source
Cadernos de Saúde PúblicaEste artigo objetiva desvelar a presença da idéia do aborto como elemento do âmbito das reflexões dos jovens sobre uma gravidez na adolescência.
Simone Ouvinha Peres +1 more
doaj
, 2011 The experience of being in employment while pregnant or returning to work after having a child is not well researched in Ireland or indeed internationally.
Russell, Helen, Banks, Joanne
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Educational pathways and outcomes for care‐experienced children: A 16‐year longitudinal study
British Educational Research Journal, EarlyView.Abstract Children who are removed from their birth families during childhood—termed care‐experienced—can be at risk for lower educational attainment and poorer school experiences, often linked to deprivation and behavioural factors. However, research often uses aggregated measures that obscure the complexities of care (e.g.
Emily Lowthian +9 more
wiley +1 more source