Results 51 to 60 of about 64,887 (307)

Investigating whether adverse prenatal and perinatal events are associated with non-clinical psychotic symptoms at age 12 years in the ALSPAC birth cohort [PDF]

, 2009
Background. Non-clinical psychosis-like symptoms (PLIKS) occur in about 15% of the population. It is not clear whether adverse events during early development alter the risk of developing PLIKS.
Lewis, G., Harrison, Gillian, Thomas, K., Gunnell, David, Lewis, Glyn, Lewis, Glyn H, Odd, D., Harrison, Glynn, Hollis, Chris, Wolke, D., Wolke, Dieter, Zammit, Stanley, Horwood, Jeremy, Thomas, Kate, Menezes, P., Hollis, C., Thompson, Andrew D., Menezes, Paulo, Horwood, James, Gunnell, D., Thompson, A.   +20 more
core   +1 more source

Pharmacological Inhibition of FKBP51 Mitigates Early Life Adversity‐Induced Social Deficits in Male Mice

Advanced Science, EarlyView.
Early life adversity triggers persistent social subordination and brain‐wide molecular dysregulation. Pharmacological inhibition of the stress‐mediator FKBP51 during the adversity period prevents these long‐term deficits and restores normative social hierarchy.
Joeri Bordes, Xiuqi Ji, Serena Gasperoni, Choham Sudre‐Chinsky, Amirali Kalbasi, Daniela Harbich, Cornelia Flachskamm, Paula Fontanet, Sowmya Narayan, Manfred Uhr, Christian Namendorf, Camilla Bellone, Alon Chen, Felix Hausch, Juan Pablo Lopez, Mathias V. Schmidt   +15 more
wiley   +1 more source

Maternal Smoking Intensity During Pregnancy and Early Adolescent Cardiovascular Health

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background The adverse cardiovascular effects of smoking are well established. We aimed to investigate the less well‐understood effects of pregnancy smoke exposure on offspring cardiovascular health in early adolescence.
Mengjiao Liu, Elna Yihui Soon, Katherine Lange, Markus Juonala, Jessica A. Kerr, Richard Liu, Terence Dwyer, Melissa Wake, David Burgner, Ling‐Jun Li   +9 more
doaj   +1 more source

Adolescent Pregnancy Desire and Pregnancy Incidence [PDF]

Women's Health Issues, 2011
Research has suggested the importance of pregnancy desire in explaining pregnancy risk behavior among adolescent females. Much of the literature, however, uses cross-sectional study designs to examine this relationship. Because bias may strongly influence these results, more prospective studies are needed to confirm the relationship between pregnancy ...
Heather L, Sipsma, Jeannette R, Ickovics, Jessica B, Lewis, Kathleen A, Ethier, Trace S, Kershaw   +4 more
openaire   +2 more sources

Better 10‐Year Cerebrovascular Outcome After Transplant Than on Standard‐Care in Sickle Cell Anemia: DREPAGREFFE Trial

American Journal of Hematology, EarlyView.
ABSTRACT Management of cerebral vasculopathy in sickle cell anemia (SCA) includes standard‐care, that is, chronic transfusion (CT) or hydroxyurea, and hematopoietic cell transplantation (HCT). DREPAGREFFE‐1 (December 2010/June 2013), a French multicenter trial, was the first prospective trial comparing standard‐care to match sibling donor (MSD)‐HCT in ...
Francoise Bernaudin, Suzanne Verlhac, Elisabeth Ducros‐Miralles, Cécile Arnaud, Isabelle Genty, Marie Petras, Catherine Paillard, Gonzalo De Luna, Benoit Meunier, Isabelle Thuret, Annie Kamdem, Corinne Pondarré, Giovanna Cannas, Christelle Chantalat‐Auger, Nadia Firah, Sophie Pertuisel, Laure Joseph, Florence Missud, Mariane de Montalembert, Corinne Guitton, Claire Pluchart, Valentine Brousse, Monique Elmaleh, Vincent Gajdos, Emmanuella Leveillé, Ekaterina Belozertseva, Mabel Gaba, Catherine Poirot, Virginie Barraud‐Lange, Philippe Chadebech, France Pirenne, Myriam Bernaudin, Bénédicte Neven, Pierre Frange, Marie Angoso, Karima Yakouben, Bénédicte Bruno, Nathalie Dhédin, Jean‐Hugues Dalle, Regis Peffault Delatour, Camille Jung   +40 more
wiley   +1 more source

Pregnant Women after Physical and Sexual Abuse in Germany [PDF]

, 2009
Background/Aims: The aim of our study was to evaluate the prevalence of abuse among pregnant women in Germany attending our antenatal outpatient clinic and to observe whether a history of abuse had consequences for women's feelings about their pregnancy.
Kaestner, Ralph, Jundt, Katharina, Knobbe, Angelika, Peschers, Ursula M., Friese, Klaus, Haertl, Kristin   +5 more
core   +1 more source

Correction of Ineffective Erythropoiesis and Normalization of Iron Homeostasis After Exagamglogene Autotemcel in Transfusion‐Dependent β‐Thalassemia

American Journal of Hematology, EarlyView.
ABSTRACT Exagamglogene autotemcel (exa‐cel) is a one‐time, ex vivo, CRISPR‐Cas9 gene edited cell therapy approved for patients with transfusion dependent β‐thalassemia (TDT) aged 12–35 years. In a Phase 3 study (CLIMB THAL‐111), exa‐cel treatment resulted in reactivation of fetal hemoglobin and increases in total hemoglobin, leading to transfusion ...
Sujit Sheth, Selim Corbacioglu, Josu de la Fuente, Mattia Algeri, Joachim Rupprecht, Kevin H. M. Kuo, Ami J. Shah, Peter Lang, Hayley Merkeley, Ben Carpenter, Markus Y. Mapara, Robert I. Liem, Stephan Grupp, Yogi Chopra, Amanda M. Li, Janet L. Kwiatkowski, Melanie Kirby‐Allen, Maria Domenica Cappellini, Antonis Kattamis, Sakellarios Zairis, Tina Liu, William Hobbs, Haydar Frangoul, Franco Locatelli, Roland Meisel, on behalf of the CLIMB THAL‐111 and CLIMB‐131 Study Groups   +25 more
wiley   +1 more source

Acardia fetal en un embarazo adolescente a propósito de un caso

Columna Médica, 2022
Introducción: Acardia fetal es una rara complicación de la gestación gemelar. Uno de los gemelos no presenta cabeza y/o corazón,por lo tantoutiliza el corazón del otro para satisfacer sus necesidades fisiológicas.
Yander Luis Izaguirre Campillo, Lizandra Pujol Arias, Blanca Margarita Angulo Peraza   +2 more
doaj  

Prevalence and risk factors of preterm birth among pregnant adolescents in Kuala Lumpur: A cross-sectional study [PDF]

Malaysian Family Physician
Introduction: Adolescent pregnancies are often associated with a higher risk of adverse outcomes, including preterm birth, which may lead to severe physiological and psychological health impacts on both mothers and children.
Nur Aznida Abu Bakar, Dalila Roslan, Nik Nairan Abdullah, Musbahiyah Mat Zainal, Puvanese Rebecca Pillai Simon   +4 more
doaj   +1 more source

Teenage pregnancy policy in England [PDF]

, 2005
This article provides an account of the development and early stages of the implementation of the teenage pregnancy policy introduced in England in 1999 (Social Exclusion Unit).
Ingham, Roger
core   +1 more source