Results 41 to 50 of about 157,912 (301)

What's the Risk? Older Women Report Fewer Symptoms for Suspected Acute Coronary Syndrome than Younger Women. [PDF]

, 2018
The purpose of the study was to determine whether older (≥65 years) and younger (<65 years) women presenting to the emergency department (ED) with symptoms suggestive of acute coronary syndrome (ACS) varied on risk factors, comorbid conditions ...
Breen, Katherine, Burke, Larisa A, DeVon, Holli A, Mirzaei, Sahereh, Robinson, Nadia, Vuckovic, Karen, Zegre-Hemsey, Jessica   +6 more
core   +2 more sources

Genetic predisposition to porto‐sinusoidal vascular disorder: A functional genomic‐based, multigenerational family study

Hepatology, EarlyView., 2022
A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...
Jingxuan Shan, André Megarbane, Aziz Chouchane, Deepak Karthik, Ramzi Temanni, Atilio Reyes Romero, Huiying Hua, Chun Pan, Xixi Chen, Murugan Subramanian, Chadi Saad, Hamdi Mbarek, Cybel Mehawej, Eliane Chouery, Sirin W. Abuaqel, Alexander Dömling, Sami Remadi, Cesar Yaghi, Pu Li, Lotfi Chouchane   +19 more
wiley   +1 more source

Effect of pregnancy induced hypertension on adverse perinatal outcomes in Tigray regional state, Ethiopia: a prospective cohort study

BMC Pregnancy and Childbirth, 2019
Background The prevalence of pregnancy-induced hypertension in Ethiopia ranges from 2.2 to 18.3%. However, so far little is known about the adverse perinatal outcomes of pregnancy-induced hypertension in Tigray regional state, Ethiopia.
Abadi Kidanemariam Berhe, Abiodun O. Ilesanmi, Christopher O. Aimakhu, Afework Mulugeta   +3 more
doaj   +1 more source

Adverse pregnancy outcomes related to chronic arterial hypertension

Revista Médica de Minas Gerais, 2023
Objective: Evaluate adverse perinatal outcomes related to previous systemic arterial hypertension (SAH). Methods: This is a case-control study conducted at Darcy Vargas Maternity Hospital, in Joinville, SC, Brazil, from August to December 2020.
Pedro Bonilauri Ferreira, Felipe Farah, Guilherme Schroder Stepic, Mateus de Miranda Gauza, Rodrigo Ribeiro e Silva, Jean Carl Silva   +5 more
doaj   +1 more source

Burden, timing and causes of maternal and neonatal deaths and stillbirths in sub-Saharan Africa and South Asia: Protocol for a prospective cohort study [PDF]

, 2016
OBJECTIVES: The AMANHI mortality study aims to use harmonized methods, across eleven sites in eight countries in South Asia and sub–Saharan Africa, to estimate the burden, timing and causes of maternal, fetal and neonatal deaths. It will generate data to
Abdul Quaiyum, Mohammad, AMANHI study group, Kalonji, Michel, Ngaima, Seige, Nguwo, Andre, Otomba, John, Tshefu, Antoinette   +6 more
core   +1 more source

Evaluation of serum lipid profiles, uric acid, and high sensitivity C‐reactive protein levels between pregnancy‐induced hypertension and normotensive pregnant women attending Ambo University Referral Hospital, Ambo, Ethiopia, 2020: A case‐control study

Health Science Reports, 2022
Background and Aims Pregnancy‐induced hypertension is one of the top three ranked diseases during pregnancy that cause maternal, fetal, and neonatal morbidity and mortality worldwide.
Bilisuma G. Areda, Solomon T. Gizaw, Delesa H. Berdida, Abbul H. Kebalo   +3 more
doaj   +1 more source

Effects of diet on hypertensive disorders during pregnancy: A cross-sectional study from a teaching hospital

Journal of Family Medicine and Primary Care, 2021
Background: Pregnancy is a positive, fulfilling experience for many, but it can put the mother at the risk of suffering ill-health, disability, or even maternal death.
Dhananjay Kumar Singh, Nikhil Sinha, Om Prakash Bera, Sheikh Mohd Saleem, Shailesh Tripathi, Deep Shikha, Manish Goyal, Sudip Bhattacharya   +7 more
doaj   +1 more source

Natural killer cells in placentation and cancer: Implications for hypertension during pregnancy [PDF]

, 2017
Hypertension during pregnancy is the most common medical condition encountered during gestation. Despite this, knowledge of the mechanisms that underlie the disease and the development of new therapies are limited.
Cornelius, Denise C., Delles, Christian, Guzik, Tomasz J., Small, Heather Yvonne   +3 more
core   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

The Placental Transcriptome in Late Gestational Hypoxia Resulting in Murine Intrauterine Growth Restriction Parallels Increased Risk of Adult Cardiometabolic Disease. [PDF]

, 2019
Intrauterine growth restriction (IUGR) enhances risk for adult onset cardiovascular disease (CVD). The mechanisms underlying IUGR are poorly understood, though inadequate blood flow and oxygen/nutrient provision are considered common endpoints.
Casero, David, Chu, Alison, Cosi, Amy, Devaskar, Sherin U, Thamotharan, Shanthie, Wadehra, Madhuri   +5 more
core   +2 more sources