Results 161 to 170 of about 823,485 (329)

Pregnancy outcomes.

open access: yesHealth reports, 1996
Live births, induced abortions, and miscarriages/stillbirths are usually examined separately. This article combines the three outcomes to focus on pregnancy in Canada from 1974 to 1992. An estimated 525,100 pregnancies ended in Canada during 1992. While this was a substantial increase from 438,300 in 1974, the pregnancy rate in 1992-77 pregnancies per ...
S, Wadhera, W J, Millar
openaire   +1 more source

Obesity‐Associated TRIM15 Promotes the Proliferation of Esophageal Adenocarcinoma Through the YY2/FOXRED1 Axis

open access: yesAdvanced Science, EarlyView.
The study identifies TRIM15 as a key driver in the development of obesity‐associated esophageal adenocarcinoma (EAC). Mechanistically, TRIM15 degrades YY2 through the proteasome pathway, suppressing FOXRED1 transcription and ultimately accelerating tumor proliferation.
Haohui Wang   +10 more
wiley   +1 more source

The Consequences of Couples’ Pregnancy Intentions for Early Parental Behaviors and Infant Health: Does It Matter Who Is Asked? [PDF]

open access: yes
Previous research has found that pregnancy intentions are predictive of some early parental behaviors and infant health outcomes. However, most studies have relied on mothers’ reports of pregnancy intentions and have examined only maternal behaviors ...
Marianne Bitler, Maureen R. Waller
core  

Antenatal placental assessment in the prediction of adverse pregnancy outcome after reduced fetal movement

open access: gold, 2018
Lucy Higgins   +4 more
openalex   +1 more source

Lnc‐HZ05 Suppresses Trophoblast Cell Migrasome Formation by Disrupting TGFβ2 Pathway in Unexplained Recurrent Miscarriage

open access: yesAdvanced Science, EarlyView.
TGFβ2 signaling‐mediated migration/invasion and migrasome formation are suppressed in recurrent miscarriage (RM) versus healthy control villous tissues and are negatively associated with unexplained RM. In mechanism, TGFβ2 promotes trophoblast cell migration/invasion and migrasome formation, all of which are suppressed by lnc‐HZ05. In details, lnc‐HZ05
Weina Chen   +14 more
wiley   +1 more source

Type II Alveolar Epithelial Cells Promote Sepsis‐Induced Immunosuppression in Alveolar Macrophages via Exosomal lncRNA Rmrp Release

open access: yesAdvanced Science, EarlyView.
The S100A4/STAT3 axis promotes Rmrp transcription in AEC‐IIs and Rmrp expression in AEC‐II‐derived exosomes. Upon entry into AMs, Rmrp binds to and blocks the ubiquitination and degradation of ZFP36. Increased ZFP36 induced Pfkfb3 mRNA decay by binding to AREs in the 3′ UTR, curbing glycolysis and immune responses of AMs and aggravating SII and ...
Chengxi Liu   +17 more
wiley   +1 more source

Hepatitis E Virus ORF1 Polyprotein Harbors a Pocket‐Like Cavity That Is Vital for Virus Replication and Represents a Novel Antiviral Target

open access: yesAdvanced Science, EarlyView.
Within the hepatitis E virus (HEV) ORF1 polyprotein, the X domain interacts with viral RNA‐dependent RNA polymerase (RdRp), forming a functional “pocket‐like” cavity (PC) that is crucial for viral replication. Structure‐based screening, surface plasmon resonance (SPR) assays, and HEV model validation collectively identify saikosaponin D and ...
Xiaohui Ding   +15 more
wiley   +1 more source

Placental malaria and adverse pregnancy outcomes in Majang Zone of Gambella Region, Southwest Ethiopia: a histopathological and molecular study [PDF]

open access: gold
Aklilu Alemayehu   +6 more
openalex   +1 more source

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