Results 231 to 240 of about 823,485 (329)

MSC Membrane‐Coated circPROSC‐siRNA Nanoparticles for Ameliorating Craniosynostosis by Inhibiting Premature Suture Ossification

open access: yesAdvanced Science, EarlyView.
CircPROSC promotes craniosynostosis by sponging miR‐6815‐5p, thereby activating WNT3A/β‐catenin signaling and enhancing RUNX2‐mediated osteogenesis. Targeted silencing of circPROSC with MSC membrane–coated siRNA nanoparticles (MM@Lipo/si‐circPROSC) delivered postnatally into cranial sutures attenuates premature suture closure in Twist1+/– mice ...
Zhenkun Weng   +6 more
wiley   +1 more source

Laeverin is Cell‐Surface Target for Liquid‐Phase Metastasizing Cancer Cells

open access: yesAdvanced Science, EarlyView.
This study revealed that epithelial cancer cells in the floating phase induce the expression of laeverin (LVRN) that is a trophoblast‐specific and cell‐surface immunoregulatory factor and showed that anti‐LVRN ADC is a promising agent that can attack cancer cells in the metastatic liquid phase and block further distant metastasis.
Haruki Kasama   +17 more
wiley   +1 more source

Does the weekend matter? evaluating the weekend effect on pregnancy outcomes in first-cycle fresh IVF/ICSI embryo transfers: a retrospective study [PDF]

open access: gold
Tianli Yang   +11 more
openalex   +1 more source

A Transmembrane Protein WAI‐B2 Confers Multiple Disease Resistance in Wheat by Activating Autoimmunity

open access: yesAdvanced Science, EarlyView.
Wheat production is under threat from multiple diseases. This study clones the wheat autoimmunity gene WAI‐B2 from an EMS‐induced mutant that encodes a distinct transmembrane protein conferring resistance to wheat rusts and powdery mildew ‐ two major diseases affecting wheat crops.
Wenling Li   +32 more
wiley   +1 more source

Heterogeneity of Gestational Diabetes and Risk for Adverse Pregnancy Outcome: A Cohort Study.

open access: yesJ Clin Endocrinol Metab
Gong Y   +13 more
europepmc   +1 more source

Ovarian Hyperstimulation and Maternal Virilisation with Successful Pregnancy Outcome: A case report. [PDF]

open access: yesSultan Qaboos Univ Med J
Al Ghaithi ISH   +6 more
europepmc   +1 more source

Enhanced Selenium Supplement Extends Lifespan and Delays Multi‐Organs Aging by Regulating the Sik1 Pathway Through Maintaining Calcium Homeostasis

open access: yesAdvanced Science, EarlyView.
Aging involves physiological decline and heightened disease susceptibility, necessitating effective interventions. Redox‐responsive selenium‐loaded nanoparticles (SeMSNs) are developed, which delay cellular senescence by reducing oxidative stress and senescence markers (p16/p21). In aged mice, SeMSNs extend lifespan, improve organ function, and restore
Yang Yu   +15 more
wiley   +1 more source

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