Results 231 to 240 of about 2,842,065 (311)

Angiogenic factors and fetal Doppler for predicting adverse pregnancy outcome in early-onset small fetuses with and without pre-eclampsia. [PDF]

open access: yesUltrasound Obstet Gynecol
Bonacina E   +13 more
europepmc   +1 more source

Structural Control of Stromal‐Immune Coupling by COL24A1 Underlies Pregnancy Maintenance

open access: yesAdvanced Science, EarlyView.
COL24A1 emerges as a collagen‐associated regulator of maternal‐fetal interface homeostasis. Its deficiency promotes a maladaptive TIMP1‐high stromal state, impaired ECM turnover, collagen accumulation, and stromal–immune dysregulation, contributing to pregnancy loss.
Teng Wu   +12 more
wiley   +1 more source

Pregnancy Outcome in Women Aged 40 Years and Above: A Cross Sectional Study. [PDF]

open access: yesJ Obstet Gynaecol India
Gupta N   +6 more
europepmc   +1 more source

Lactate Signal: Modulator of Cellular Energy Production and Anabolism

open access: yesAdvanced Science, EarlyView.
Compartmentalized lactate signaling provides a spatial framework for understanding how lactate‐rich states are generated, transported, sensed, and translated into biological outputs. This Review integrates extracellular, cytosolic, mitochondrial‐associated, and nuclear lactate mechanisms to explain how lactate shapes metabolic adaptation, immune ...
Han Wang, Si‐Yuan Yang, Wei Xu
wiley   +1 more source

Cellular Mechanisms Enabling Mitochondria Transfer and Transplantation

open access: yesAdvanced Science, EarlyView.
Mitochondrial transfer and transplantation (mitoTT) is examined as a multistep process governed by distinct transfer routes and post‐transfer checkpoints. Mechanisms controlling mitochondrial uptake, network integration, cristae remodeling, mtDNA maintenance, immune sensing, and quality control are highlighted, revealing key biological and ...
F. Seyma Gokdemir   +3 more
wiley   +1 more source

One‐Step Induction of Oogonia‐Like and Pro‐Spermatogonia‐Like Cells From Porcine Pluripotent Stem Cells

open access: yesAdvanced Science, EarlyView.
This study established a one‐step method inducing pro‐spermatogonia‐like (activating SOX17) and oogonia‐like (activating SOX17/TFAP2C) cells from porcine pgEpiSCs with a NANOS3‐tdTomato reporter. EGF activates the core PGC program and supports survival; BMP4 further induces NANOS3 and DDX4 expression; IWR1 enhances PGCLC efficiency by suppressing ...
Pengcheng He   +14 more
wiley   +1 more source

A Biomimetic cRGDyk‐Engineered Platelet Nanoplatform for ACAD11 Delivery to Trigger Pyroptosis in Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
A biomimetic platelet nanoplatform (OE‐ACAD11@R‐PLT) is developed for targeted hepatocellular carcinoma immunotherapy. By selectively delivering therapeutic plasmids, this system induces mitochondrial dysfunction and triggers robust NLRP3/Caspase‐1/GSDMD‐mediated pyroptosis in tumor cells.
Hongyi Bao   +12 more
wiley   +1 more source

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