Results 91 to 100 of about 455,628 (245)

Baseline Neuroinflammation Stratifies TSPO‐PET Response to Disease‐Modifying Therapy in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate which baseline clinical and imaging characteristics best predict TSPO‐PET‐measurable reduction in glial activation following treatment of multiple sclerosis (MS), to utilize this information for designing more efficient biomarker‐based clinical trials targeting glial activation.
Marlene T. Morch, Markus Matilainen, Giulia N. Baldrighi, Marjo Nylund, Maija Saraste, Laura Airas   +5 more
wiley   +1 more source

Association between low maternal serum aflatoxin B1 exposure and adverse pregnancy outcomes in Mombasa, Kenya, 2017–2019: A nested matched case–control study

Maternal and Child Nutrition
We examined the association between serum aflatoxin B1‐lysine adduct (AFB1‐lys) levels in pregnant women and adverse pregnancy outcomes (low birthweight, miscarriage and stillbirth) through a nested matched case–control study of pregnant women enroled at
Eric Osoro, Abigael O. Awuor, Irene Inwani, Cyrus Mugo, Elizabeth Hunsperger, Jennifer R. Verani, Ruth Nduati, John Kinuthia, Lydia Okutoyi, Dufton Mwaengo, Brian Maugo, Nancy A. Otieno, Harriet Mirieri, Cynthia Ombok, Bryan Nyawanda, George O. Agogo, Isaac Ngere, Nicholas C. Zitomer, Michael E. Rybak, Peninah Munyua, Kariuki Njenga, Marc‐Alain Widdowson   +21 more
doaj   +1 more source

Predictive Value of Composite Inflammatory Markers for Stroke Prognosis: A Prospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Novel composite inflammatory markers' role in stroke prognosis is understudied, and the best predictor is unclear, requiring further exploration. Objectives This study aimed to systematically evaluate the associations of 6 novel composite inflammatory markers on stroke prognosis.
Bing Wu, Jie‐Jie Li, Jing Jing, Jin‐Xi Lin, Xia Meng, Yong Jiang, Yong‐Jun Wang, Hong‐Qiu Gu   +7 more
wiley   +1 more source

The relationship between glucose patterns in OGTT and adverse pregnancy outcomes in twin pregnancies

Journal of Diabetes
Background Traditional fixed thresholds for oral glucose tolerance test (OGTT) results may inadequately prevent adverse pregnancy outcomes in twin pregnancies. This study explores latent OGTT patterns and their association with adverse outcomes.
Wei‐Zhen Tang, Qin‐Yu Cai, Yi‐Fan Zhao, Hao‐wen Chen, Xia Lan, Xia Li, Li Wen, Ying‐Xiong Wang, Tai‐Hang Liu, Lan Wang   +9 more
doaj   +1 more source

Temporal Interference Stimulation of Centromedian‐Parafascicular Complex in Disorders of Consciousness: A Pilot Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu, Changgeng Song, Dianwei Wu, Xiaoqian Niu, Jianmin Hao, Lijuan Liu, Xiaogang Kang, Wen Jiang   +7 more
wiley   +1 more source

Clinical application of hysteroscopic decidual polypectomy in pregnant women

BMC Pregnancy and Childbirth
Objective This study aims to explore the clinical efficacy and safety of hysteroscopic decidua polypectomy during pregnancy. Methods This retrospective study analyzed 38 patients presenting with recurrent vaginal bleeding due to pregnancy-associated ...
Yi Yu, Dongdong Shi, Long Sui, Hongwei Zhang, Limei Chen   +4 more
doaj   +1 more source

Evidence-based directed acyclic graphs for perinatal pharmacoepidemiologic studies in rheumatology: a structured approach for development and implementation in administrative health data

Frontiers in Epidemiology
BackgroundEvidence-based Directed Acyclic Graphs (DAGs) are effective tools to comprehensively visualize complex causal and biasing pathways in pharmacoepidemiologic research in rheumatology. This paper outlines the process of developing and implementing
Vienna Cheng, Vienna Cheng, Vienna Cheng, Neda Amiri, Neda Amiri, Neda Amiri, Vicki Cheng, Vicki Cheng, Jacquelyn J. Cragg, Jacquelyn J. Cragg, Jacquelyn J. Cragg, Laurie Proulx, Laurie Proulx, Mary A. De Vera, Mary A. De Vera, Mary A. De Vera, Mary A. De Vera   +16 more
doaj   +1 more source

Impact of Age on the Diagnostic Yield of Routine EEG in People With Childhood or Juvenile Absence Epilepsy: A Cross‐Sectional Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background We aimed to identify the proportion of individuals with a confirmed diagnosis of childhood absence epilepsy (CAE) or juvenile absence epilepsy (JAE) who show a negative routine EEG (rEEG), and to determine the main factors associated with this finding.
Francesco Fortunato, Alessia Giugno, Miriam Sturniolo, Enrico Fratto, Pio Zoleo, Francesca Felicia Operto, Ilaria Sammarra, Antonio Gambardella   +7 more
wiley   +1 more source

The association between dyslipidaemia in the first trimester and adverse pregnancy outcomes in pregnant women with subclinical hypothyroidism: a cohort study

Lipids in Health and Disease
Background Subclinical hypothyroidism (SCH) is linked to dyslipidaemia and adverse pregnancy outcomes. However, the impact of dyslipidaemia on the outcome of pregnancy in SCH is unclear.
Xueran Wang, Enjie Zhang, Zongyuan Tian, Rong Zhao, Kaikun Huang, Shen Gao, Shaofei Su, Shuanghua Xie, Jianhui Liu, Yingyi Luan, Yue Zhang, Zheng Zhang, Yousheng Yan, Wentao Yue, Chenghong Yin, Ruixia Liu   +15 more
doaj   +1 more source

Risk of Retinopathy Associated with Long‐Term Use of Hydroxychloroquine in Patients with Rheumatic Diseases: A Systematic Review and Meta‐Analysis

Arthritis Care &Research, EarlyView.
Objective We aimed to estimate the prevalence and cumulative incidence of hydroxychloroquine retinopathy (HCQ‐R) and its risk factors among patients receiving long‐term HCQ with rheumatic diseases through a systematic review and meta‐analysis of observational studies that used spectral‐domain optical coherence tomography (SD‐OCT) for screening ...
Narsis Daftarian, Chloe Yue, Steve D Levasseur, Hui Xie, J. Antonio Avina‐Zubieta   +4 more
wiley   +1 more source