Results 231 to 240 of about 912,768 (303)

Multi-Omics for Mothers and Infants (MOMI) Consortium: a global initiative to study adverse pregnancy outcomes. [PDF]

J Glob Health
Tang X, Ahmed S, Ahmed FB, Albrecht V, Brennsteiner V, Chang AL, Chowdhury NH, Deb S, Gormley M, Hasan T, Kamulaza L, Khalid J, Khan W, Khanam R, Kshetrapal P, Luo H, Maiti TK, Maitra A, Mannan MM, Mueller-Reif J, Mulenga C, Nisar I, Pervin J, Pokaprakarn T, Price J, Qazi MF, Rittenhouse K, Sebastiao Y, Sindano N, Sinha T, Sopory S, Steger M, Thiruvengadam R, Wadhwa N, Xue L, Aghaeepour N, Baqui AH, Bhatnagar S, Fisher S, Fox M, Hampel D, Kasaro M, Mann M, Rahman A, Sazawal S, Shenhav L, Stringer JS, Zhang G, Jehan F, De Paris K.   +49 more
europepmc   +1 more source

The Landscape and Regulation of Histone Crotonylation in Mammalian Gametes and Early Embryos

Advanced Science, EarlyView.
Histone crotonylation undergoes a genome‐wide transition from broad domains to canonical narrow peaks during minor zygotic genome activation (ZGA). This remodeling is required for proper major ZGA and blastocyst formation. Disruption of this transition by transcriptional inhibition, metabolic perturbation, or HDAC1 dysfunction impairs embryonic ...
Shenli Yuan, Yelian Yan, Yalin Liang, Kanghua Zhong, Zhican Fu, Xiaobo Wang, Chao Liu, Tao Huang, Keliang Wu   +8 more
wiley   +1 more source

Association of uterine fibroids with adverse pregnancy outcomes: a retrospective cohort study. [PDF]

BMC Pregnancy Childbirth
Wu J, Zhang X.
europepmc   +1 more source

Nanoplastics and Neurodegeneration: A Roadmap From Mechanism to Causation

Advanced Science, EarlyView.
Nanoplastics are pervasive environmental contaminants with potentially profound implications for human health. Emerging evidence suggests a possible link between nanoplastic exposure and neurodegeneration, a key driver of ageing and dementia, yet causality remains unresolved.
Yuhuan Li, Yue Wang, Xiufang Liang, Mengze Xu, David T. Leong, Pu Chun Ke   +5 more
wiley   +1 more source

Vaginoscopic polypectomy for cervical polyps during pregnancy: an analysis of safety and influencing factors for pregnancy outcomes. [PDF]

Front Med (Lausanne)
Zhao H, Li H, Zhu Z, Yang B, Gao W, Feng L.   +5 more
europepmc   +1 more source

Dual‐Mode Type I/II Photosensitization of a Stable Mesoporous Hydrogen‐Bonded Organic Framework for Antibacterial Therapy

Advanced Science, EarlyView.
A π‐conjugated donor–acceptor PDI monomer undergoes hydrogen‐bonded self‐assembly to form a robust mesoporous framework. The ordered molecular arrangement promotes efficient intersystem crossing and charge separation, leading to simultaneous Type I and Type II reactive oxygen species generation with a high singlet oxygen quantum yield.
Yi‐Lun Cheng, Hui Yuan, Yuhang Li, Zi‐Yu Wang, Rui Wang, Qi Yin, Xue‐Ning Ren, Miao Zheng, Yi Zeng, Tian‐Fu Liu, Zaisheng Ye   +10 more
wiley   +1 more source

Impact of intrapartum cervical tear on subsequent pregnancy outcomes. [PDF]

BMC Pregnancy Childbirth
Dreyfuss E, Fischer O, Seidman L, Bercovich O, Mash Y, Hadar E, Romano A, Houri O.   +7 more
europepmc   +1 more source

Fosl2 Regulates FSH‐Dependent Follicle Maturation Through Feedback Amplification of FSH/FSHR Signaling

Advanced Science, EarlyView.
This study identifies a FOSL2‐driven positive feedback loop that amplifies FSH/FSHR signaling. During FSH‐dependent follicle maturation, FSH induces Fosl2 expression via the cAMP‐PKA‐CREB cascade. FOSL2 in turn binds the promoters of Fshr and estrogen‐biosynthesis genes to enhance their transcription, thereby increasing Fshr mRNA level and amplifying ...
Hongru Shi, Chaoli Chen, Zaohong Ran, Jianning Liao, Zian Wu, Xiaodong Wang, Yongheng Zhao, Wenkai Ke, Bowen Tan, Yun Liu, Youqiang Su, Wei Ren, Xiang Li, Changjiu He   +13 more
wiley   +1 more source

Pregnancy Outcomes Associated With Anemia in the First Trimester and Anemia Resolution by Late Pregnancy. [PDF]

Obstet Gynecol
Booman A, Bateman BT, Siadat S, Berube C, Igbinosa I, Leggett C, Lyell DJ, Main EK, Leonard SA.   +8 more
europepmc   +1 more source

Rational Design of Broad‐Spectrum Anti‐Enteroviral Molecular Glues Targeting Enteroviral RNAi Suppressors

Advanced Science, EarlyView.
By leveraging this homodimerization mechanism, molecular glues were rationally designed to induce dysfunctional 3A dimerization, thereby restoring antiviral RNAi. The optimal molecular glue, VTP‐32, demonstrated potent and pan‐enterovirus (groups A, B, D) antiviral effects.
Yuan Fang, Xiong Xie, Huidi Fan, Botao Wu, An Wang, Wenhao Dai, Zezhong Liu, Jian Li, Huoyan Tong, Jianan Li, Yujie Ren, Jinlin Wang, Xi Zhou, Hong Liu   +13 more
wiley   +1 more source