Results 51 to 60 of about 1,093,029 (362)

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Teenage pregnancy in Africa: trends and determinants in the 21st century [PDF]

open access: yes, 2016
Background: Africa remains one of the continents with the highest levels of teenage pregnancies in the world. In spite of this, there are limited empirical research studies on determinants of teenage pregnancy in Africa.
Bellingham-Young, Denise   +1 more
core   +3 more sources

Sincronização de estro com CIDR reutilizado em cabras lactantes da raça Toggenburg tratadas com somatotropina bovina recombinante (r-bST) Estrous synchronization with recycled CIDR in lactating Toggenburg does treated with recombinant bovine somatotropin (r-bST)

open access: yesArquivo Brasileiro de Medicina Veterinária e Zootecnia, 2008
Avaliou-se a resposta de cabras tratadas com r-bST no protocolo de sincronização de estro. Foram utilizadas 26 cabras Toggenburg, divididas em dois tratamentos: T1 (n=13), tratadas com quatro injeções de 250mg de r-bST, a intervalos de 14 dias, e T2 (n ...
E.A.M. Amorim   +8 more
doaj   +1 more source

Evaluation of Prognostic Factors for Clinical Pregnancy Rate Following Artificial Insemination by Husband in the Chinese Population

open access: yesFrontiers in Medicine, 2021
Background: To determine the independent prognostic factors and develop a multivariate logistic regression model for predicting successful pregnancy following artificial insemination by husband (AIH) in infertile Chinese couples.Methods: A total of 3,015
Yumei Luo   +16 more
doaj   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Effects of GnRH administration on ovulation and fertility in ewes subjected to estrous synchronization

open access: yesRevista Brasileira de Zootecnia, 2012
The objective of this study was to verify the effects of GnRH on ovulation and pregnancy of ewes subjected to a short-term synchronization of estrus. Santa Inês and crossbred Santa Inês/Dorper ewes received 60 mg MAP sponges during 6 days plus 300 IU eCG
Amanda dos Santos Cavalcanti   +3 more
doaj   +1 more source

Laparotomic intrauterine insemination with frozen-thawed semen in Sopravissana breed ewes in Central Italy

open access: yesItalian Journal of Animal Science, 2021
Intrauterine laparoscopic insemination is diffuse in sheep breeding, yet requires veterinary expertise and expensive equipment. Our aim was to evaluate the time required, reproductive outcome and post-operative complications of mini invasive laparotomic ...
Lakamy Sylla   +5 more
doaj   +1 more source

Epidemiologic aspects of neural tube defects in South East Iran [PDF]

open access: yes, 2006
Objectives: To investigate the rate of neural tube defects (NTDs) and their relation to gender, maternal age, consanguineous marriage, season, and drug consumption in Birjand, Iran.
Afshar, M., Farhud, D., Golalipour, M.J.
core  

Self-reported pregnancy exposures and placental DNA methylation in the MARBLES prospective autism sibling study. [PDF]

open access: yes, 2016
Human placenta is a fetal-derived tissue that offers a unique sample of epigenetic and environmental exposures present in utero. In the MARBLES prospective pregnancy study of high-risk younger siblings of children with autism spectrum disorder (ASD ...
Barkoski, Jacqueline M   +8 more
core   +2 more sources

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