Results 11 to 20 of about 11,486 (263)

Cross-sectional study of chromosomal aberrations and immunologic factors in Iraqi couples with recurrent pregnancy loss

, 2022
Background Parental chromosomal aberrations are important causes of recurrent pregnancy loss (RPL). Some immunological factors such as antiphospholipid antibodies and interleukin-6 (IL-6) also contribute to this complication. The aim of this study was to
Doaa A. Khamees, Mushtak T. S. Al-Ouqaili   +1 more
core   +1 more source

Stress associated miscarriage: immunologic and endocrinologic parameters in early pregnancy

, 2007
Titelblatt und Inhaltsverzeichnis Einleitung Material und Methoden Ergebnisbeschreibung Diskussion LiteraturverzeichnisProblem: Aborte zählen zu den häufigsten Schwangerschaftskomplikationen.
Bärenstrauch, Nina
core   +1 more source

Prenatal maternal immune disruption and sex-dependent risk for psychoses [PDF]

, 2014
BackgroundPrevious studies suggest that abnormalities in maternal immune activity during pregnancy alter the offspring's brain development and are associated with increased risk for schizophrenia (SCZ) dependent on sex.MethodUsing a nested case-control ...
M. Hornig, M. T. Tsuang, L. J. Seidman, Cherkerzian, S, Remington, AG, Seidman, LJ, Donatelli, J-AL, Hornig, M, Tsuang, MT, S. Cherkerzian, A. G. Remington, Goldstein, JM, J.-A. L. Donatelli, J. M Goldstein, S. L. Buka, Buka, SL   +15 more
core   +1 more source

Universal testing and treatment as an HIV prevention strategy: research questions and methods. [PDF]

, 2011
Achieving high coverage of antiretroviral treatment (ART) in resource-poor settings will become increasingly difficult unless HIV incidence can be reduced substantially.
Sarah Fidler, Kalpana Sabapathy, Sabapathy, Kalpana, Hayes, Richard, Fidler, Sarah, Richard Hayes   +5 more
core   +1 more source

Recurrent pregnancy loss. [PDF]

, 1994
journal articleRecurrent pregnancy loss is a frustrating clinical dilemma for both patients and physicians because, in most cases, causes are nebulous and few treatments with proven benefit can be offered.
Varner, Michael W.; Hatasaka, Harry H.
core  

Carbamylation of β2-GPI generates new autoantigens for antiphospholipid syndrome. a new tool for diagnosis of "seronegative" patients

, 2022
Objectives: Antiphospholipid syndrome (APS) is a prothrombotic condition defined by recurrent thrombosis, pregnancy complications and circulating antiphospholipid antibodies (aPL), including anti-β2-Glycoprotein I (β2-GPI).
Gloria Riitano, Elisabetta Profumo, Tina Garofalo, Roberta Misasi, Maurizio Sorice, Valeria Manganelli, Simona Truglia, Antonella Capozzi, Fabrizio Conti, Brigitta Buttari, Silvia Mancuso, Serena Recalchi, Cristiano Alessandri, Agostina Longo, Vincenzo Mattei   +14 more
core   +1 more source

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano, Giacomo Boffa, Maria Petracca, Marta Ponzano, Nicole Graziano, Claire Wigley, Claire Riley, Jonathan Howard, Pietro Bontempi, Sylvia Klineova, Fred Lublin, Matilde Inglese   +11 more
wiley   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Sex Differences in Medication Discontinuation in Axial Spondyloarthritis

Arthritis Care &Research, EarlyView.
Objective We examined sex differences in medication discontinuation among patients with axial spondyloarthritis (axSpA) initiating tumor necrosis factor inhibitors (TNFi), interleukin‐17 inhibitors (IL‐17i), or JAK inhibitors (JAKi). Methods Using data from the Rheumatology Informatics System for Effectiveness (RISE) Registry (2003–2025), we assessed ...
Rachael Stovall, Cinthia Blat, Eric Roberts, Jean W. Liew, Katherine Wysham, Namrata Singh, Janna Friedly, Lianne S. Gensler, Gabriela Schmajuk, Jinoos Yazdany   +9 more
wiley   +1 more source

Risk of Retinopathy Associated with Long‐Term Use of Hydroxychloroquine in Patients with Rheumatic Diseases: A Systematic Review and Meta‐Analysis

Arthritis Care &Research, EarlyView.
Objective We aimed to estimate the prevalence and cumulative incidence of hydroxychloroquine retinopathy (HCQ‐R) and its risk factors among patients receiving long‐term HCQ with rheumatic diseases through a systematic review and meta‐analysis of observational studies that used spectral‐domain optical coherence tomography (SD‐OCT) for screening ...
Narsis Daftarian, Chloe Yue, Steve D Levasseur, Hui Xie, J. Antonio Avina‐Zubieta   +4 more
wiley   +1 more source