Results 81 to 90 of about 291,006 (308)

First trimester diagnosis of monoamniotic twin pregnancies [PDF]

Ultrasound in Obstetrics & Gynecology, 2000
AbstractThis study reports the ultrasound findings and pregnancy outcome for a series of monoamniotic twin pregnancies diagnosed at 11–14 weeks' gestation. Of 315 monochorionic twin pregnancies examined, there were 12 (3.8%) monoamniotic, including four sets of conjoined twins (1.3%).
Sebire, N J, Souka, A, Skentou, H, Geerts, L, Nicolaides, K H   +4 more
openaire   +3 more sources

Tacrolimus exposure during pregnancy in kidney and liver transplantation recipients: A comparison between whole blood and plasma concentration‐to‐dose ratios

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Tacrolimus monitoring is generally performed in whole blood (WB). Most (>85%) of circulating tacrolimus is bound to red blood cells. During pregnancy, WB monitoring might be suboptimal because of physiological changes including increased plasma volume and decreased haematocrit.
Jildau R. Meinderts, Paola Mian, Frederike G. I. van Vilsteren, Karien M. H. van de Wetering, Jelmer R. Prins, Stefan P. Berger, Daan J. Touw, Margriet F. C. de Jong   +7 more
wiley   +1 more source

Serum thyroxin level during the first-trimester of pregnancy [PDF]

, 2011
Objective: The aim of this study was to assess the requirement of serum thyroxin levels during the early stage of the first trimester of pregnancy. Methodology: Serum thyroxin levels of 120 apparently healthy women were evaluated in Gorgan in northern ...
Mansourian, A.R., Mansourian, H.R., Saifi, A.   +2 more
core  

Zuranolone: A case study in (regulatory) rush to judgement?

British Journal of Clinical Pharmacology, EarlyView.
Abstract Sage, in collaboration with Biogen, submitted a new drug approval for zuranolone for postpartum depression (PPD) and major depressive disorder (MDD) in December 2022. In August 2023, the US Food and Drug Administration granted approval for PPD but denied approval for MDD.
Lisa Cosgrove, Milutin Kostic, Barbara Mintzes, Gianna D'Ambrozio, Allen Shaughnessy   +4 more
wiley   +1 more source

Safety of Amlodipine in Early Pregnancy

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Amlodipine is used for the treatment of hypertension, but reports on its use in early pregnancy are limited. Methods and Results In the present study, we recruited 231 women with chronic hypertension, including those who received amlodipine or
Asako Mito, Atsuko Murashima, Yoshinao Wada, Mai Miyasato‐Isoda, Chizuko A. Kamiya, Masako Waguri, Jun Yoshimatsu, Naho Yakuwa, Omi Watanabe, Tomo Suzuki, Naoko Arata, Masashi Mikami, Shinya Ito   +12 more
doaj   +1 more source

Fasting Glucose Metabolism in Pregnancy [PDF]

, 2011
The HAPO study found a continuous association between hyperglycemia at 24-32 weeks of gestation, below the diagnostic levels of gestational diabetes mellitus (GDM), and adverse pregnancy outcomes, suggesting the need to reconsider the diagnostic criteria
Ferreira, C., Matos, Ana, Moura, P., Pereira, S., Silva, V.   +4 more
core  

Atazanavir and lopinavir profile in pregnant women with HIV: tolerability, activity and pregnancy outcomes in an observational national study [PDF]

, 2014
Background: Atazanavir and lopinavir represent the main HIV protease inhibitors recommended in pregnancy, but comparative data in pregnant women are limited. Methods: Women from a national observational study, exposed in pregnancy to either atazanavir or
. . . ]., Anna Degli Antoni, Anna Maria Marconi, Arsenio Spinillo, CAPRETTI, MARIA GRAZIA, Carmela Pinnetti, Daniela Francisci, Enrica Tamburrini, FALDELLA, GIACOMO, Giulia Masuelli, Giuseppina Liuzzi, Marco Floridia, Marina Ravizza, MARSICO, CONCETTA, Marta Fiscon, on behalf of The Italian Group on Surveillance on Antiretroviral Treatment in Pregnancy [. . ., Pasquale Martinelli, Vania Giacomet   +17 more
core   +1 more source

Use of antiemetics in early pregnancy 2012–2022: A cross‐sectional study

British Journal of Clinical Pharmacology, EarlyView.
Aim Nausea and vomiting in pregnancy impact quality of life, yet many pregnant women feel dismissed by healthcare professionals, despite the safety of first‐line antiemetic treatments for both mother and fetus. Therefore, this study aims to describe the prevalence of patient‐reported antiemetic use in early pregnancy in Copenhagen, Denmark, the changes
Katrine Bak Wraae, Nanna Roed Ballegaard, Mie Lærkeholm Hede, Line Buchgreitz, Ane Lilleøre Rom, Hanne Kristine Hegaard, Nina Olsén Nathan   +6 more
wiley   +1 more source

The decline of 6‐thioguanine nucleotides is not linked to impaired efficacy or safety of thiopurines in pregnant women with inflammatory bowel disease

British Journal of Clinical Pharmacology, EarlyView.
Background Thiopurines are used to maintain remission in inflammatory bowel disease (IBD). These drugs are metabolized into 6‐thioguanine nucleotides (6‐TGN), associated with efficacy, and 6‐methylmercaptopurine ribonucleotides (6‐MMPR), associated with adverse drug reactions. Pregnancy has been linked to a shift in thiopurine metabolism, characterized
Dianne G. Bouwknegt, Paola Mian, Femke Groen, Denise van den Berg‐Zuiddam, Andrea E. van der Meulen, Femke Crouwel, Nanne K. de Boer, Debbie S. Deben, Dennis R. Wong, Luc J. J. Derijks, Gerard Dijkstra, Arno R. Bourgonje, C. Janneke van der Woude, Marijn C. Visschedijk   +13 more
wiley   +1 more source

Successful treatment of maternal listeria monocytogenes bacteremia in the first trimester of pregnancy: A case report and literature review

Taiwanese Journal of Obstetrics & Gynecology, 2018
Objective: To report detailed clinical history and management of maternal listeria infection in the first trimester. Case report: A 34-year-old woman at 11 gestational weeks was infected by Listeria monocytogenes with clinical symptoms of acute onset of ...
Lai-Man Chan, Ho-Hsiung Lin, Sheng-Mou Hsiao   +2 more
doaj   +1 more source