Results 251 to 260 of about 235,181 (316)

Target Hopping from Protein Kinases to PXR: Identification of Small-Molecule Protein Kinase Inhibitors as Selective Modulators of Pregnane X Receptor from TüKIC Library. [PDF]

Cells, 2022
Mustonen EK, Pantsar T, Rashidian A, Reiner J, Schwab M, Laufer S, Burk O.   +6 more
europepmc   +1 more source

The Major Human Pregnane X Receptor (PXR) Splice Variant, PXR.2, Exhibits Significantly Diminished Ligand-Activated Transcriptional Regulation [PDF]

, 2009
Yvonne S. Lin, Kazuto Yasuda, Mahfoud Assem, Cynthia Cline, Joe Barber, Chia-Wei Li, Vladyslav Kholodovych, Ni Ai, J. Don Chen, William J. Welsh, Sean Ekins, Erin G. Schuetz   +11 more
openalex   +1 more source

Human Pregnane X Receptor Activation and CYP3A4/CYP2B6 Induction by 2,3-Oxidosqualene:Lanosterol Cyclase Inhibition [PDF]

, 2009
Zofia Duniec‐Dmuchowski, Hai-Lin Fang, Stephen C. Strom, Ewa Ellis, Melissa Runge‐Morris, Thomas A. Kocarek   +5 more
openalex   +1 more source

Upregulation of antioxidants and chemoresistance genes in human granulosa cells following Pregnane X receptor activation: a potential role for fertility preservation [PDF]

, 2009
Sana M. Salih, A. Kapur, Samet Albayrak, Charles L. Bormann   +3 more
openalex   +1 more source

Interplay between the Nuclear Receptor Pregnane X Receptor and the Uptake Transporter Organic Anion Transporter Polypeptide 1A2 Selectively Enhances Estrogen Effects in Breast Cancer

, 2008
Henriette E. Meyer zu Schwabedissen, Rommel G. Tirona, Cindy S. Yip, Richard Ho, Richard B. Kim   +4 more
openalex   +1 more source

P253 - The role of pregnane X receptor (PXR/NR1I2) gene variants in inflammatory bowel disease [PDF]

, 2009
Julia Seiderer, J Glas, Julia Diegelmann, D Fischer, B. Seitz, Simone Pfennig, Thomas Griga, Wolfram Klein, Jörg T. Epplen, U Schiemann, Thomas Mussack, Burkhard Göke, Thomas Ochsenkühn, Matthias Folwaczny, Bertram Müller‐Myhsok, Stephan Brand   +15 more
openalex   +1 more source

Pregnane X receptor knockout mitigates weight gain and hepatic metabolic dysregulation in female C57BL/6 J mice on a long-term high-fat diet. [PDF]

Biomed Pharmacother
Gebreyesus LH, Choi S, Neequaye P, Mahmoud M, Mahmoud M, Ofosu-Boateng M, Twum E, Nnamani DO, Wang L, Yadak N, Ghosh S, Gonzalez FJ, Gyamfi MA.   +12 more
europepmc   +1 more source

Stereoselective interactions of warfarin enantiomers with the pregnane X nuclear receptor in gene regulation of major drug‐metabolizing cytochrome P450 enzymes [PDF]

, 2010
Alice Rulcová, Ilona Prokopová, Lucie Krausová, Michal Bitman, Radim Vrzal, Zdeněk Dvořák, J Blahoš, Petr Pávek   +7 more
openalex   +1 more source

Correction: Structural and Functional Similarity of Amphibian Constitutive Androstane Receptor with Mammalian Pregnane X Receptor.

PLoS ONE, 2014
doaj   +3 more sources

Drug discovery technologies to identify and characterize modulators of the pregnane X receptor and the constitutive androstane receptor.

Drug Discovery Today, 2019
S. Chai, Wenwei Lin, Yongtao Li, Taosheng Chen   +3 more
semanticscholar   +1 more source