Results 281 to 290 of about 1,191,573 (331)

Acute Poisonings, Suicidality and Systemic Inflammatory Load in Pregnant Women. [PDF]

Psychiatry Clin Psychopharmacol
Koçakoğlu Ş, Büyükaslan H.
europepmc   +1 more source

An Explainable Multimodal Artificial Intelligence Model Integrating Histopathological Microenvironment and EHR Phenotypes for Germline Genetic Testing in Breast Cancer

Advanced Science, EarlyView.
This study presents an explainable multimodal AI model, MAIGGT (Multimodal Artificial Intelligence Germline Genetic Testing), that combines whole‐slide histopathology with clinical data for accurate germline BRCA1/2 mutation prescreening. By integrating digital pathology and EHR phenotypes, MAIGCT enables cost‐effective, scalable hereditary breast ...
Zijian Yang, Changyuan Guo, Jiayi Li, Yalun Li, Lei Zhong, Pengming Pu, Tongxuan Shang, Lin Cong, Yongxin Zhou, Guangdong Qiao, Ziqi Jia, Hengyi Xu, Heng Cao, Yansong Huang, Tianyi Liu, Jian Liang, Jiang Wu, Dongxu Ma, Yuchen Liu, Ruijie Zhou, Xiang Wang, Jianming Ying, Meng Zhou, Jiaqi Liu   +23 more
wiley   +1 more source

Red Blood Cell Membrane Lipidomics: Potential Biomarkers Detecting Method for Plasma Volume Overload and Major Adverse Cardiovascular Events in Chronic Heart Failure Patients

Advanced Science, EarlyView.
A novel RBC indicator, ESI, is better than the traditional RBC indicators and is associated with CHF prevalence and in‐hospital death. RBC membrane lipidomics, Cer 18:0;O2/16:0, and LPE 18:0, are associated with plasma volume overload and MACE in CHF patients, but these plasma lipids could not.
Lin Zhang, Xiangqin Ou, Jingyi Lin, Xiaofei Luo, Jiashun Zhou, Xingyue Zhou, Peihua Zhao, Li Liu, Ziran Zhao, Ying Zhou, Guanwei Fan, Lifeng Han, Xiumei Gao   +12 more
wiley   +1 more source

Perinatal outcomes in RhD-negative pregnant women in Japan. [PDF]

Sci Rep
Takahashi K, Yoshida S, Aoki S, Tanaka S, Kawashima A, Kajiwara K, Kato N, Matsui H, Serizawa M, Tsuji S, Yamamoto T, Kinjo T, Nakamura N, Sagawa M, Sato M, Abe E, Nakanishi S, Fujimoto Y, Takahashi S, Sasaki H, Mukai Y, Hara S, Fukuta K, Kikuchi N, Hara E, Shiga T, Horiuchi C, Sado T, Matsubara Y, Akabane K, Harada A, Nagase H, Maeda K, Katagiri H, Sasahara J, Sugii H, Tamaru S, Waratani M, Tsukahara S, Shibukawa S, Kiyama T, Kasuga Y, Egawa M, Sato H, Tamamura C, Suemitsu T, Okamoto A, Samura O.   +47 more
europepmc   +1 more source

Discovery to Engineering of Mycotoxin Deoxynivalenol Degrading Enzymes Based on the Specialized Glyoxalase I

Advanced Science, EarlyView.
Deoxynivalenol (DON), a prevalent food mycotoxin, is an important risk factor in global food safety. A molecular phylogeny‐guided engineering approach is devised to repurpose specialized glyoxalase I (SPG) as a DON deactivator. Engineered SPG variants demonstrate superior stability and are highly capable of converting DON into less toxic products ...
Seung Hee Lee, Song Lim Ham, Kyoungmi Oh, Hyojin Park, Young‐Seo Kang, Tae‐Joo Yang, Taekyung Kim, Jonghwan Kim, Gyu Sung Lee, Min‐Jeong Lee, Jin‐Byung Park, Chung Sub Kim, Nam Yoon Kim   +12 more
wiley   +1 more source

AI‐Driven Defecation Analysis by Smart Healthcare Toilet: Exploring Biometric Patterns and Eu‐Tenesmus

Advanced Science, EarlyView.
A healthcare toilet system is introduced to passively measure defecation behavior. Real‐time data on stool dropping duration, thickness, and a newly defined “eu‐tenesmus” interval show correlations with stool form and gender differences. Results from 45 defecation events reveal a promising method for comprehensive defecation analysis.
Zhiquan Song, TaeHyung Kwon, Jeung Lee, Daeyoun D. Won, Brian J. Lee, Hyuk Soon Choi, Joseph C. Liao, Walter G. Park, Irene Sonu, Stephan Rogalla, Michael J. Rosen, David L. Hu, Jonathan Kuang Ziyang, Sunny Hei Wong, Bong Hyun Jun, Soh Kim, Seung‐min Park   +16 more
wiley   +1 more source

Serology survey of chikungunya virus in high-risk pregnant women and placental tissue findings. [PDF]

Rev Inst Med Trop Sao Paulo
Fajardo TCG, Quadros Junior AC, Pinto CAL, Santos GRD, Silva ACBD, Catalan DT, Bertozzi APAP, Gazeta RE, Moron AF, Passos SD, Jundiai Zika Cohort Group, Mello AS, Soriano-Arandes A, Alarcon A, Garcia-Alix A, Silva ABD, Ventura DF, Oliveira DBL, Tambalo DS, Lima DDS, Fujiwara DT, Durigon EL, Bagne ER, Velasco FG, Baran LCP, Arita FN, Hernandez FDM, Almeida JPG, Camandulli KR, Castro LP, Machado MB, Zatz M, Rodrigues MMD, Rizzo MFV, Farrão MA, Leite MNB, Florence Filho N, Loiola PC, Prestes R, Dezena RCA, Bonon SHA, Vranjac S, Rosemberg S, Sarmento SGP, Witkinchi SS, Souza TG, Pandini VCM, Paiva VP.   +47 more
europepmc   +1 more source

Cellular Adaptation to Mechanical Stress Emerges via Cell Shrinkage Triggered by Nonlinear Calcium Elevation

Advanced Science, EarlyView.
Here, a decision‐making mechanism underlying mechanical adaptation is demonstrated. This study demonstrates that cellular adaptation to mechanical stress can be induced by applying low‐amplitude stretch to cells. When the stretch reaches a critical amplitude threshold, it triggers Ca2⁺‐dependent positive feedback, which induces cholesterol efflux and ...
Zhengyan Wang, Zihan Li, Lei Wang, Haitao Zhang, Xiaoshan Yang, Lili Bao, Geng Dou, Lili Ren, Yajing Fu, Lan Li, Shengkai Gong, Yang Zhou, Feng Ding, Lu Yu, Haotian Luo, Yao Liu, Fuyang Zhang, Hui Yu, Siying Liu, Xueming Liu, Fulan Wei, Shiyu Liu   +21 more
wiley   +1 more source

Investigating health literacy and its associations with fear of childbirth in pregnant women: a cross-sectional study. [PDF]

Sci Rep
Bakouei S, Ahmari Tehran H, Jafarbegloo E, Bakouei F.   +3 more
europepmc   +1 more source