Results 91 to 100 of about 34,944 (258)

Opioid Toxicity Following Concomitant Use of Macrolide Antibiotics with Fentanyl, Hydromorphone, or Oxycodone: A Population‐Based Study

Clinical Pharmacology &Therapeutics, Volume 120, Issue 1, Page 122-138, July 2026.
Fentanyl, hydromorphone, and oxycodone are metabolized by cytochrome P450 3A4 (CYP3A4). Co‐administration with CYP3A4‐inhibiting macrolides (clarithromycin or erythromycin) may increase opioid concentrations and overdose risk, but the clinical impact of these interactions is unknown.
Tony Antoniou, Joanna Yang, David N. Juurlink, Joanne M.‐W. Ho, Muhammad Mamdani, Fangyun Wu, Mina Tadrous, Tara Gomes   +7 more
wiley   +1 more source

Association of Suspected Aspiration During of Out‐Of‐Hospital Cardiac Arrest With Development of Early‐Onset Pneumonia

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 6, July 2026.
ABSTRACT Background Early‐onset pneumonia is a possible complication after out‐of‐hospital cardiac arrest (OHCA) resuscitation. Whether or not a suspected aspiration during prehospital care is associated with the development of early‐onset pneumonia has not been studied.
Karoliina Yli‐Luukko, Paula Mäki, Sanna Hoppu, Piritta Setälä, Joonas Tirkkonen   +4 more
wiley   +1 more source

Medication Appropriateness in Prehospital Care

Emergency Medicine International, 2019
Background. The aim of the present study was to determine the medication appropriateness (MA) in prehospital emergency physician deployments according to the hospital discharge diagnosis and to investigate the factors influencing the MA. Methods. The MA was determined by a systematic comparison of the administered medication in prehospital emergency ...
Nikolai Ramadanov, Roman Klein, Abner Daniel Aguilar Valdez, Wilhelm Behringer   +3 more
openaire   +3 more sources

Prehospital Use of Non‐Invasive Ventilation for Acute Respiratory Failure due to Acute Exacerbation of Chronic Obstructive Pulmonary Disease. A Randomised Trial

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 6, July 2026.
ABSTRACT Background In‐hospital use of non‐invasive ventilation improves outcomes in patients with acute respiratory failure caused by acute exacerbation of chronic obstructive pulmonary disease. Prehospital use of non‐invasive ventilation is uncommon due to diagnostic uncertainty and logistical constraints.
Jesper H. Brendel, Lars W. Andersen, Søren H. Skaarup, Thomas Dissing, Anders Gunnar Nielsen, Nikolaj F. Milandt, Ulrick S. Espelund, Lisa F. Irion, Lone R. Mortensen, Kim M. Larsen, Jens Aage K. Petersen   +10 more
wiley   +1 more source

Early Versus Late Wake‐Up Call After Out‐Of‐Hospital Cardiac Arrest: Protocol for a Multicenter Randomized Comparison Within the Danish Out‐of‐Hospital Cardiac Arrest (DANOHCA) Trial

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 6, July 2026.
ABSTRACT Background Survivors of out‐of‐hospital cardiac arrest (OHCA) who remain comatose after return of spontaneous circulation are routinely sedated and mechanically ventilated during early post‐resuscitation care. Although prolonged sedation has traditionally been considered necessary, contemporary normothermia‐based temperature control allows ...
Anders Morten Grejs, Jesper Kjaergaard, Jo Bønding Andreasen, Bodil Steen Rasmussen, Christian Hassager, Martin Abild Stengaard Meyer, Lars Peter Kloster Andersen, Henrik Schmidt, Simon Moelstroem, Sören Möller, Christhopher Torp, Steffen Christensen, Jacob Eifer Moeller   +12 more
wiley   +1 more source

Emotional distress of callers requesting emergency medical communication center assistance and patient outcomes: a prospective observational study

BMC Emergency Medicine
Background Telephone triage, performed in Emergency Medical Communication Centers is the complex task of gathering key medical information in order to identify life-threatening emergencies and ensure timely and appropriate service deployment.
Marie Christina Ng Ping Cheung, Juline Beringer, Lionel Moulis, Joana Pissarra, Sophie Lefebvre, Mustapha Sebbane   +5 more
doaj   +1 more source

Subcutaneous Tranexamic Acid Achieves Comparable Serum Concentrations to Intramuscular Administration During Haemorrhagic Shock in a Swine Model

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 6, July 2026.
ABSTRACT Background Tranexamic acid is an antifibrinolytic agent reducing mortality when administered to trauma patients with haemorrhagic shock. This mortality reduction is time sensitive. Increased intramuscular dose administration has proven an effective alternative to intravenous administration in several studies and is used by some emergency ...
Trine Lynghaug, Ole Martin Fuskevåg, Benjamin Stage Storm, Erik Waage Nielsen, Bent Aksel Nilsen, Erik Sveberg Dietrichs, Håkon Kvåle Bakke   +6 more
wiley   +1 more source

A hybrid strategy using an ambulance and a helicopter to convey thrombectomy candidates to definite care: a prospective observational study

BMC Emergency Medicine
Background Mechanical thrombectomy is the treatment of choice for large vessel occlusion strokes done only in comprehensive stroke centres (CSC). We investigated whether the transportation time of thrombectomy candidates from another hospital district ...
Pauli Vuorinen, Piritta Setälä, Jyrki Ollikainen, Sanna Hoppu   +3 more
doaj   +1 more source

A Novel Approach to Cadaver‐Based Soiled Airway Simulation

AEM Education and Training, Volume 10, Issue 3, June 2026.
ABSTRACT Effective management of heavily soiled airways is a critical and challenging skill across multiple clinical settings. Existing training methods rely largely on manikin‐based simulators, which often lack sufficient anatomical realism and haptic fidelity.
Adam Parks, Sean Hurley, Patricia Marks, James Gould   +3 more
wiley   +1 more source

Concrete silo collapse: emergency medical services response to a mass casualty incident

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Background Major incidents evolving from occupational accidents are very infrequent in Scandinavia and therefore, case reports are called for. On 26 November, 2024, a fatal occupational accident took place during the construction of a concrete silo in ...
Peter Martin Hansen, Marius Rehn, Rasmus Peter Jakobsen, Jesper Byrdorf, Simon Hestbech Lundorff, Søren Mikkelsen   +5 more
doaj   +1 more source