Results 101 to 110 of about 712,503 (299)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Supersymmetry Without Prejudice at the LHC
, 2011 The discovery and exploration of Supersymmetry in a model-independent fashion will be a daunting task due to the large number of soft-breaking parameters in the MSSM. In this paper, we explore the capability of the ATLAS detector at the LHC ($\sqrt s=14$
A. Djouadi +71 more
core +2 more sources
Understanding prejudice of psychic suffering individuals about sexuality
Revista Brasileira de EnfermagemObjectives: to understand the conceptions of individuals in psychological distress about their sexuality. Methods: qualitative study held at a Psychosocial Care Center. Fifteen people assisted in the service participated. A semi-structured questionnaire
Gisela Cardoso Ziliotto +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Psychologica Belgica, 2017 We test two assumptions of the generalized prejudice literature. First, that the structure of generalized prejudice (i.e. how prejudices are interrelated) is dependent on the intergroup context.
Cecil Meeusen +2 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Examining prejudice reduction through solidarity and togetherness experiences among Gezi Park activists in Turkey [PDF]
, 2016 Prejudice reduction research has focused on reducing negative regard as a means to improve relations between various groups (e.g., religious, ethnic, political).
Blee +13 more
core +3 more sources
Journal of Social and Political Psychology, 2018 Understanding the complex manifestations of sexual stigma is crucial in helping to prevent discrimination toward sexual minorities. In this research, we examined the role of heterosexism within political ideology systems and the process through which ...
Crystal L. Hoyt, Mitchell Parry
doaj +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source