Results 131 to 140 of about 65,072 (307)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Democratic Thwarting of Majority Rule in Opinion Dynamics: 1. Unavowed Prejudices Versus Contrarians

open access: yesEntropy
I study the conditions under which the democratic dynamics of a public debate drives a minority-to-majority transition. A landscape of the opinion dynamics is thus built using the Galam Majority Model (GMM) in a 3-dimensional parameter space for three ...
Serge Galam
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Стереотипы, установки, предрассудки и предубеждения в профессиональной педагогической деятельности сельских учителей

open access: yesНаучно-педагогическое обозрение
Рассматривается вопрос формирования новых стереотипов профессиональной педагогической деятельности, которые могут заменить негативные и устаревшие, деструктивно влияющие на результат труда сельских учителей, который, по сравнению с городскими ...
Пивоварова Анна Викторовна
doaj   +1 more source

Pride & Prejudice [PDF]

open access: yesJournal of Periodontal & Implant Science, 2010
openaire   +2 more sources

Multicultural Education and Racial Prejudices in Children

open access: yes, 2019
This poster examines the impact of multicultural education on school-aged children’s concepts of racial prejudices in the classroom setting, and the significance of their teachers’ multicultural awareness in facilitating equitable curriculum and ...
Rodgers, Rikki
core  

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

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