Results 51 to 60 of about 2,311,006 (294)

Statistical Analysis on Preliminary Breakdown Pulses of Positive Cloud-to-Ground Lightning in Malaysia

, 2016
This aim of this paper is to study the preliminary breakdown pulses (PBP) of positive cloud-to-ground (+CG) lightning flashes in Malaysia. There is a difference in PBP characteristics when a comparison is made between positive and negative flashes.
C. Wooi, Z. Abdul-Malek, Noor Azlinda Ahmad, Mehrdad Mokhtari, B. Salimi   +4 more
semanticscholar   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Possible Protective Role of NLRC4 Inflammasome in Periodontal Diseases: A Preliminary Study

Dental Hypotheses, 2021
Introduction: Inflammasomes are multiprotein complexes, which regulate proinflammatory cytokines, Interleukin-18 (IL-18), and Interleukin-1β (IL-1β) that are associated with periodontal breakdown.
Sneha Parameswaran, Vanaja Krishna Naik, Kubra Aral, Sugirtharaj Gunasekaran, Devapriya Appukuttan, Michael R Milward, Ramya Ramadoss   +6 more
doaj   +1 more source

Correlation analysis between initial preliminary breakdown process, the characteristic of radiation pulse, and the charge structure on the Qinghai‐Tibetan Plateau

, 2016
Using synchronous data from a three‐dimensional lightning VHF radiation source mapping system, broadband electric field changes, and the radiation intensity of lightning on the Qinghai‐Tibetan Plateau, we divided the preliminary breakdown process into ...
Bin Wu, Guang-shu Zhang, Junsong Wen, Tong Zhang, Yajun Li, Yanhui Wang   +5 more
semanticscholar   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Experience on 3D Silicon Sensors for ATLAS IBL

, 2014
3D silicon sensors, where plasma micro-machining is used to etch deep narrow apertures in the silicon substrate to form electrodes of PIN junctions, represent possible solutions for inner pixel layers of the tracking detectors in high energy physics ...
Darbo, Giovanni
core   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Differential associations between apolipoprotein E alleles and cerebral myelin content in normative aging

NeuroImage, 2022
Mounting evidence indicates that myelin breakdown may represent an early phenomenon in neurodegeneration, including Alzheimer's disease (AD). Understanding the factors influencing myelin synthesis and breakdown will be essential for the development and ...
Curtis Triebswetter, Matthew Kiely, Nikkita Khattar, Luigi Ferrucci, Susan M. Resnick, Richard G. Spencer, Mustapha Bouhrara   +6 more
doaj   +1 more source

The collapse of the local, Spitzer-Haerm formulation and a global-local generalization for heat flow in an inhomogeneous, fully ionized plasma [PDF]

, 1983
The breakdown of the classical (CBES) field aligned transport relations for electrons in an inhomogeneous, fully ionized plasma as a mathematical issue of radius of convergence is addressed, the finite Knudsen number conditions when CBES results are ...
Olbert, S., Scudder, J. D.
core   +1 more source