British Journal of Clinical Pharmacology, EarlyView.Abstract Aims This work assessed the pharmacokinetics (PK), safety and tolerability of glasmacinal (EP395, an oral anti‐inflammatory macrolide with negligible antimicrobial activity in development for COPD treatment) in two healthy participant trials: ‘first‐in‐human’ (FIH) and ‘drug–drug‐interaction’ (DDI).
Dave Singh +5 more
wiley +1 more source
Dilemmas in the development of the general practitioner workforce in primary care: a qualitative study in Beijing, China. [PDF]
BMJ OpenCui Y +8 more
europepmc +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aim To develop and validate a physiologically‐based pharmacokinetic (PBPK) model enabling inhaled oxytocin dose selection for clinical evaluation. Subsequently, to conduct a phase 1 study investigating the pharmacokinetics and safety of selected doses of an optimized inhaled oxytocin product in healthy, non‐pregnant female participants.
Pete Lambert +6 more
wiley +1 more source
Factors associated with occupational calling among psychiatric nurses: a Bayesian network model analysis. [PDF]
Sci RepAi Y, Liao Q, Shen X.
europepmc +1 more source
The future in a bubble: Supporting Finnish early childhood professionals working in diverse settings
British Educational Research Journal, EarlyView.Abstract The purpose of this study was to contribute to the knowledge about early childhood education and care (ECEC) personnel's perception of the support structures that are most effective in assisting them in their work with culturally and linguistically diverse children.
Alexandra C. Anton +2 more
wiley +1 more source
Focusing on legal cases: Automatic classification of legal documents with sentence embeddings and deep learning models. [PDF]
PLoS OneAlarfaj FK.
europepmc +1 more source
Understanding the paradox of primary teacher shortage in low‐income countries: Insights from Malawi
British Educational Research Journal, EarlyView.Abstract Malawi faces a persistent and chronic teacher shortage, particularly at the primary school level, with much of the challenge attributed to teacher supply constraints. While the causes of teacher shortages are known to be complex and context‐dependent, there remains a lack of in‐depth, country‐specific research to guide effective policies ...
Peter Mtika, Edward M. Sosu
wiley +1 more source
Towards a Nitinol-Based Microfabricated Approach to Repair Long-Gap Esophageal Atresia. [PDF]
Micromachines (Basel)Domingues AR +11 more
europepmc +1 more source
British Educational Research Journal, EarlyView.Abstract The intersection of economic conditions and early years education has long been debated, particularly where financial constraints shape educational practice and professional realities. Türkiye, characterised by high inflation and structural vulnerabilities in purchasing power parity, provides a critical context for examining how economic ...
Ebru Aydın, Şerif Yüksel
wiley +1 more source
Positioning Community Pharmacies in Nigeria as a Clinical Trial Partner: A Forward Perspective. [PDF]
Clin Transl SciBamgboye AO +4 more
europepmc +1 more source