Results 211 to 220 of about 883,299 (307)

Multifunctional Gold Nanocluster‐Based PROTAC System for Targeted Degradation of Phosphorylated Tau and Modulation of Neuroinflammation in Alzheimer's Disease

Advanced Functional Materials, EarlyView.
We present a novel proteolysis‐targeting chimera (PROTAC) system conjugated to lipoic acid gold nanoclusters (PLANC), designed to degrade pTau, regulate inflammatory signaling, and effectively traverse the blood‐brain barrier (BBB). PLANC degraded pTau at various phosphorylation sites, with mechanistic studies confirming proteasome‐mediated degradation
Sarah Nevins, Callan D. McLoughlin, Wan‐Kyu Ko, Hye Kyu Choi, Brandon Conklin, Joshua B. Stein, Yannan Hou, Hongwon Kim, Rohan Khulbe, Ki‐Bum Lee   +9 more
wiley   +1 more source

Advances in Sustainable and Wearable Textile Based Soft Robotics

Advanced Functional Materials, EarlyView.
This Review examines advances in wearable textile‐based soft robotics, focusing on sustainable materials, integrated sensing, and scalable actuation. It discusses manufacturing and system integration across healthcare, assistive robotics, prosthetics, and human–machine interfaces, and highlights key challenges in circular design, including life‐cycle ...
Zahir Abbas, Marzia Dulal, Sophia K. Novoselov, Victoria K. Novoselov, Kostya S. Novoselov, Shaila Afroj, Nazmul Karim   +6 more
wiley   +1 more source

A Preliminary Open-Label Pilot Study of a Pillow-Based ELF-ELME (Extremely Low-Frequency, Extremely Low Magnetic Environment) Intervention for Major Depressive Disorder. [PDF]

Neuropsychopharmacol Rep
Tomita I, Tachibana M, Nawa Y, Ito M, Kinoshita F, Kuwatsuka Y, Mori D, Ikeda M, Ohno K, Inada T.   +9 more
europepmc   +1 more source

Structure‐Guided Dynamical Mechanics in Bioinspired Double Twisted Laminated Thin Films

Advanced Functional Materials, EarlyView.
This work explores a dynamic mechanistic study of crack propagation and puncture testing via real‐time monitoring of crack initiation, propagation, and termination through nature‐inspired single and double twisted architectures fabricated from cellulose nanocrystals.
Justin Brackenridge, Olivia Harper, Jaejun Lee, Sergio Gonzalez‐Munoz, Vladimir V. Tsukruk   +4 more
wiley   +1 more source

Preliminary Quantitative MRI Assessment After Combined Posterior Endoscopic Cervical Discectomy and Foraminotomy: An Exploratory Retrospective Cohort Study. [PDF]

J Clin Med
Sienkiel T, Jasiewicz B, Taterra D, Gąska M, Koszyk P, Machajewski K, Gądek A.   +6 more
europepmc   +1 more source

Surprising Water Slipping Performance on Highly Hydrophilic PEG‐Derived Monolayer‐Covered Surfaces: Preparation, Mechanism, and Application

Advanced Functional Materials, EarlyView.
Highly hydrophilic surfaces (water contact angle, ≈17.7°) exhibiting surprising water slipping performance (sliding angle, ≈7.3°) are successfully prepared via simple chemisorption of polyethylene glycol (PEG) organosilane and subsequent alkali‐treatment.
Hyeonjin Kim, Kouki Akaike, Jerred Wassgren, Hiroshi Kakiuchida, Masahisa Okada, Atsushi Hozumi   +5 more
wiley   +1 more source

Architecting three-dimensional reconfigurable matter from pop-up kirigami with programmable multistability. [PDF]

Sci Adv
Zhou T, Huang C, Zhao H, Liu J, Liu K, Chen D, Li Y.   +6 more
europepmc   +1 more source

Coupling Anodic Activity and Stability at Ni‐Based Non‐Oxide Catalysts via Coordinating Alcohol Oxidation and Oxygen Evolution

Advanced Functional Materials, EarlyView.
A cooperative and competitive interrelationship between alcohol oxidation (AOR) and water oxidation (OER) was observed on a typical anode catalyst of Ni2P. In situ Raman spectroscopy and electrochemical analyses revealed a specific complementary mechanism between them, in which OER and AOR critically contribute to the activity and stability of anodic ...
Yong Yan, Xinyu Liu, Yuguo Zhao, Hanwen Jian, Huan Zhou, Riyi Zhang, Dong Wang, Peter Schaaf, Lihua Wang, Guangsheng Guo, Xiayan Wang   +10 more
wiley   +1 more source

Double‐Interpenetrating Composite Bioink for Multi‐Component 3D Bioprinting and Biofabrication

Advanced Functional Materials, EarlyView.
Marine‐polysaccharides‐derived double interpenetrating network hydrogel‐based bioink, combining the attributes of physical and ionic crosslinking, enables room‐temperature bioprinting of mechanically defined structures that can be handled and are cytocompatible.
Fabian Tribukait‐Riemenschneider, V. Prasad Shastri   +1 more
wiley   +1 more source

Specific design strategies for elderly-friendly residential spaces in nursing homes: an integrated model approach based on empathy map-KANO-AHP-PUGH. [PDF]

Front Psychol
Jintao Z, Weisong G, Ning Z, Lei W.
europepmc   +1 more source