Results 51 to 60 of about 7,097,764 (236)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

‘“Grow Up!”: Rethinking the Preliminary Reference Procedure from the Perspective of Maturity’

open access: yesLSE Law Review, 2021
The clash between the German Constitutional Court and the CJEU in May 2020 over economic policy highlights the growing tension between the EU and the courts of last instance in Member States. This article argues that such tensions demand a legal order which respects national judicial hierarchies, and thereby becoming mature.
openaire   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Strasbourg’s Consideration of Article 267 TFEU and the ECtHR as a Shadow Constitutional Court of the European Union

open access: yesGerman Law Journal
In this Article I argue that the European Court of Human Rights (ECtHR) exercises an under-acknowledged power to shape the constitutional norms of the EU’s legal order—a power that extends beyond that court’s role in influencing the interpretation of ...
Róisín Áine Costello
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Preliminary reference procedure within the scope of European judicial system

open access: yes, 2009
Diplomová práce se zabývá řízením o předběžné otázce. Je zde nastíněna nejen charakteristika a vývoj řízení o předběžné otázce, ale také výklad pojmu "soud členského státu" či problematika výjimek z povinnosti předložit předběžnou otázku. V následujících
Zvárová, Daniela
core   +1 more source

PRELIMINARY REFERENCE PROCEDURE AND THE SCOPE OF JUDICIAL REVIEW OF THE EUROPEAN COURT OF HUMAN RIGHTS

open access: yesEU AND COMPARATIVE LAW ISSUES AND CHALLENGES SERIES, 2019
The purpose of this paper is to examine the scope of the ECtHR’s review of preliminary reference procedure provided for in Article 267 TFEU, insofar as it concerns the right to a fair trial and other procedural safeguards read into substantive rights of the ECHR. In Ullens de Schooten and Rezabek v.
Majić, Helena, Mintas Hodak, Ljerka
openaire   +2 more sources

Preliminary ruling in Serbian civil procedure [PDF]

open access: yes, 2012
This paper analyses the sections of the Serbian Law on Civil Procedure pertaining to the so-called procedure for preliminary adjudication of an issue of law (preliminary ruling procedure), which enable the court of first instance in an ongoing litigation
Salma Marija
core   +2 more sources

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

open access: yesFEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng   +8 more
wiley   +1 more source

Preliminary rulings in criminal matters after Lisbon: the experience of Estonian courts

open access: yesTalTech Journal of European Studies
This article examines the operation and limits of the preliminary reference procedure under Article 267 of the TFEU in criminal proceedings, drawing on the experience of Estonian courts following the entry into force of the Lisbon Treaty.
Aiaots Laura, Soo Anneli
doaj   +1 more source

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