Results 101 to 110 of about 224,919 (256)
Transportation Research Interdisciplinary PerspectivesEco-driving cruising strategies can effectively reduce energy demand and contribute to extend the range of full electric vehicles. However, the adoption of these strategies, involving alternating cycles of acceleration and deceleration as a replacement ...
Haoxiang Xue +4 more
doaj +1 more source
PRELIMINARY REFERENCE PROCEDURE – THE RIGHT, THE DUTY AND EXCEPTIONS
InterEULawEast : Journal for the international and european law, economics and market integrations, 2014 According to decentralized character of the EU legal system, national courts are the ordinary courts in matters of EU law and should as such guarantee effective legal protection of individual’s rights deriving from EU law. To ensure uniform application of EU law provisions and especially to prevent possible divergent interpretations, a preliminary ...
openaire +2 more sources
Association Between Motor Pathway Damage and Motor Deficit in Upper and Lower Limb in People With MS
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Corticospinal tract damage is common in people with MS, but the degree of clinical symptoms varies. We hypothesize that corticospinal tract lesions are more extensive and severe in people with MS with motor impairments in both upper and lower limbs.
Mathilde Liffran +13 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe +7 more
wiley +1 more source
A Standards-Based Reference AI Business Model Canvas
SystemsThis study proposes a standards-based Reference AI Business Model Canvas (Reference AI-BMC) that translates the use-case descriptors of ISO/IEC TR 24030 into the nine blocks of the Business Model Canvas, addressing the lack of a structured translation ...
Junki Yang, Ja-Hee Kim
doaj +1 more source
Early Recognition of Treatment‐Responsive Rapidly Progressive Dementia: The Modified STAM3mP Score
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Early identification of patients with treatment‐responsive rapidly progressive dementia (RPD) is important as early treatment improves outcomes. The STAM3P score identifies treatment‐responsive RPD using “high risk” presenting features. We optimized performance by adding a time component (i.e., dementia within 3 months) and validated the ...
R. W. van Steenhoven +16 more
wiley +1 more source
AR‐assisted surgery: Precision placement of patient specific hip implants based on 3D printed PSIs
Healthcare Technology LettersPatient‐specific implant placement in the case of pelvic tumour resection is usually a complex procedure, where the planned optimal position of the prosthesis may differ from the final location.
Amaia Iribar‐Zabala +11 more
doaj +1 more source
White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian +8 more
wiley +1 more source
Prominent Movement Disorders in RNU2‐2‐Related Spliceosomopathy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Pediatric movement disorders often overlap with neurodevelopmental diseases, suggesting shared molecular mechanisms. Variants in small nuclear RNA (snRNA) genes encoding spliceosome components have recently been associated with neurodevelopmental disorders, termed “RNUopathies.” We analyzed genome sequencing data from 14 patients with ...
Magdalena Krygier +6 more
wiley +1 more source