Results 41 to 50 of about 1,272,715 (288)

Solid-state interferometric interrogator and multiplexer for high-speed dynamic and absolute FBG wavelength measurement [PDF]

open access: yes, 2013
We present a solid-state FBG array interrogator and multiplexer capable of determining absolute FBG wavelengths and of providing high-speed, high-resolution static and dynamic measurements.
Fusiek, Grzegorz   +3 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Explore the Silence: The Absence of Preliminary References from Greek Courts on Migration and Asylum

open access: yesGerman Law Journal
The preliminary reference procedure is a crucial tool for EU law enforcement. Yet, its usage varies greatly across the Member States. This paper deals with a notable case in which EU justice has not been mobilized: Greece.
Virginia Passalacqua
doaj   +1 more source

The Oxindole Derivatives, New Promising GSK-3β Inhibitors as One of the Potential Treatments for Alzheimer’s Disease—A Molecular Dynamics Approach

open access: yesBiology, 2021
The glycogen synthase kinase 3β (GSK-3β) is a protein kinase involved in regulating numerous physiological processes such as embryonic development, transcription, insulin action, cell division cycle and multiple neuronal functions.
Przemysław Czeleń, Beata Szefler
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

The Preliminary Reference Procedure and Questions of International and National Law [PDF]

open access: yesYearbook of European Law, 2009
It is common ground that whilst the European Court of Justice is the authoritative arbiter on the construction of Community law, it is not the primary enforcer thereof. Instead, the founding fathers of the Community opted for a system whereby enforcement of Community law was left, in the first place, to the Member State courts.
openaire   +2 more sources

A Remotely Controlled Calibrator for Chemical Pollutant Measuring-Units [PDF]

open access: yes, 2007
The increasing diffusion of pollutant measuring units, which are installed over wide areas, along with the short calibration interval of several sensors for pollutant quantities, requires new calibration infrastructures to be developed.
Carullo, Alessio   +2 more
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

The 2024 Reform of the EU Judicial System and the Transformation of the Court of Justice into a Constitutional Court

open access: yesEuropean Papers
(Series Information) European Papers - A Journal on Law and Integration, 2025 10(3), 837-862 | Article | (Table of Contents) 1. Introduction. – 2. Approaching constitutionalisation. – 3.
Tanja Hilpold
doaj   +1 more source

Installed performance assessment of a boundary layer ingesting distributed propulsion system at design point [PDF]

open access: yes, 2016
Boundary layer ingesting systems have been proposed as a concept with great potential for reducing the fuel consumption of conventional propulsion systems and the overall drag of an aircraft.
Goldberg, Chana   +3 more
core   +1 more source

Home - About - Disclaimer - Privacy