Results 71 to 80 of about 1,272,715 (288)

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Procedeu de determinare rapidă a speciilor de Candida în medicamente

One Health & Risk Management, 2023
PROCEDURE FOR RAPID DETERMINATION OF CANDIDA SPECIES IN DRUGS Introduction. The contamination of drugs with unauthorized microorganisms poses a significant risk in the pharmaceutical industry, as it has the potential to compromise product integrity ...
Nicolae PUȘCAȘ, Greta BĂLAN
doaj  

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

EU Procedural Law Revisited: The Reformed EU Judicial Architecture between the Statute of the Court of Justice and the Rules of Procedure

European Papers
(Series Information) European Papers - A Journal on Law and Integration, 2025 10(2), 293-326 | Article | (Table of Contents) 1. Introduction: scope and purposes of the analysis. – 2.
Lorenzo Grossio, Davor Petrić
doaj   +1 more source

The ECJ Preliminary Reference Procedure: Two to Tango?

European Taxation
This article comments on the dialogue and cooperation between the ECJ and the referring court in the context of a preliminary ruling procedure. The author discusses how the ECJ and the referring court can influence and improve this relationship. Important elements of dialogue include questions, answers and process.
openaire   +2 more sources

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

The obligation of national Courts against whose decision there is no judicial remedy to refer questions to the Court of Justice of the European Union

Journal of Legal Studies, 2016
The present paper presents the obligation that courts in the member states of the European Union have to refer questions to the Court of Justice of the European Union, with a focus on courts against whose decision there is no judicial remedy under ...
Neamt Valentin Paul
doaj   +1 more source

Trust Issues? Article 99 RoP Reasoned Orders in the Preliminary Reference Procedure

Erasmus Law Review
This article explores reasoned orders issued by the Court of Justice (the Court) to reply to preliminary references of the national courts in the procedure for a preliminary ruling of Article 267 TFEU. Reasoned orders allow the Court to reply in a swiftly manner to preliminary references that raise no doubts.
MOBILE - Center of Excellence for Global Mobility Law, Lucía López Zurita   +1 more
openaire   +2 more sources

To Refer or Not to Refer, That Is the (Preliminary) Question: Exploring Factors Which Influence the Participation of National Judges in the Preliminary Ruling Procedure

Croatian Yearbook of European Law and Policy, 2020
This paper explores factors that either motivate or constrain national judges’ participation in the preliminary ruling procedure. By incorporating insights and evidence from American judicial politics literature and drawing from three models of judicial decision making: the attitudinal model, the team model, and the resource management model, it places
openaire   +6 more sources

An electronic system for measuring thermophysical properties of wind tunnel models [PDF]

An electronic system is described which measures the surface temperature of a small portion of the surface of the model or sample at high speeds using an infrared radiometer.
Corwin, R. R., Kramer, J. S.
core   +1 more source