Results 141 to 150 of about 284,067 (289)

Ligand‐Induced Electronic Response Enables Predictive QM/MM Simulations

Advanced Science, EarlyView.
Quantum mechanics/molecular mechanics (QM/MM) simulations are powerful tools for modeling complex molecular systems; however, their predictability has been constrained by the ambiguous definition of the QM region. An electronically informed protocol is introduced that defines QM regions by quantifying guest‐induced orbital shifts and charge ...
Nichika Ozawa, Nahoko Kuroki, Hirotoshi Mori   +2 more
wiley   +1 more source

ChatGPT in Oral Pathology: Bright Promise or Diagnostic Mirage. [PDF]

Medicina (Kaunas)
Suárez A, Freire Y, Díaz-Flores García V, Santamaría Laorden A, Orejas Pérez J, Suárez Ajuria M, Algar J, Martín Carreras-Presas C.   +7 more
europepmc   +1 more source

Polarization‐Dependent 3D Holography Generated by Inverse Design Nanoprinting Metasurface

Advanced Science, EarlyView.
A novel polarization‐dependent 3D holography is proposed by introducing polarization as an additional freedom, enabling enhanced depth selectivity and greater control over holographic reconstruction. The efforts perfectly combine the polarization and 3D holography display into ADAM gradient descent algorithm, the application of nanoprinting further ...
Lingxing Xiong, Jintao Gong, Fei Zhang, Wenhao Miao, Qiong He, Dapeng Zhang, Yangjian Cai, Nan Chi   +7 more
wiley   +1 more source

Assessment of sexual function and its association with quality of life and disease severity in patients with atopic dermatitis. [PDF]

An Bras Dermatol
Bressan A, Troncoso N, Machado CJ, Cortez de Almeida RF, Carneiro S.   +4 more
europepmc   +1 more source

Colorectal Cancer Cell's Weapon: RNF32 Engages SPP1+ Macrophages to Foster Liver Metastasis, Targeted by Indole‐3‐Acetic Acid

Advanced Science, EarlyView.
Cytoplasmic RNF32 fuels CRC liver metastasis by degrading GSK3β, which stabilizes β‐catenin and activates Wnt/EMT. Moreover, RNF32 rewires the metastatic niche: it depletes CD8+/CD4+ T and NK cells while recruiting SPP1+ macrophages (which boost tumor stemness via CD44), fibroblasts, and immunosuppressive monocytes to aid colonization.
Hongyu Wang, Shipeng Dai, Yuchen Xie, Pengyu Chen, Yue Chai, Chongyu Wang, Xueying Huang, Xiao Dong, Junfeng Shi, Yongxiang Xia, Xiaofeng Qian, Weiwei Tang, Yichan Zhou   +12 more
wiley   +1 more source

Development of a Hybrid Cervical Spine Clearance Algorithm in Trauma: Tackling the Challenges of the NEXUS Criteria and Canadian Cervical Spine Rule Utilization in a Low-Volume Tertiary Neuroscience Unit. [PDF]

Cureus
Ajah HE, Nzekwu OO.
europepmc   +1 more source

Topological Defects in Carbon Matrix Are Efficiently Constructed by Joule Thermal Shock for Catalyzing the Growth of Carbon Nanotubes

Advanced Science, EarlyView.
The Joule thermal shock technique ensures the efficient construction of topological defects in the carbon matrix because the instantaneous cooling suppresses the graphitization rearrangement of the heteroatom removal sites. This topological defect carbon can activate carbon source molecules by electron transfer, and further grow into carbon nanotubes ...
Bin Wang, Shizhen Dong, Guoan Xie, Yanling Yu, Nuoxin Wang, Huakun Liu, Xian Jian, Jinyang Li, Zuowan Zhou, Jianhui Qiu   +9 more
wiley   +1 more source

The night is dark and full of hesitation. The latest step in the legal trajectory of assisted suicide in Italy: through tentative judicial openings, bioethical contradictions and the Parliament's deafness. [PDF]

Front Pharmacol
Frati P, Albore M, Ertola EM, Del Prete S, Sorace L, La Russa R, Bolino G.   +6 more
europepmc   +1 more source

SpatialESD: Spatial Ensemble Domain Detection in Spatial Transcriptomics

Advanced Science, EarlyView.
ABSTRACT Spatial transcriptomics (ST) measures gene expression while preserving spatial context within tissues. One of the key tasks in ST analysis is spatial domain detection, which remains challenging due to the complex structure of ST data and the varying performance of individual clustering methods. To address this, we propose SpatialESD, a Spatial
Hongyan Cao, Gaiqin Liu, Jingyi Xia, Runle Chen, Tong Wang, Xiaoling Yang, Ruiling Fang, Yanhong Luo, Ping Zeng, Hongmei Yu, Yanbo Zhang, Yuehua Cui   +11 more
wiley   +1 more source

Large Language Models Perform at Chance Level in the Diagnosis of Pediatric Pneumonia Using Chest Radiographs. [PDF]

Cureus
Gillette J, Lu M, Heston TF.
europepmc   +1 more source