Results 141 to 150 of about 1,435,725 (299)

Diagnosis of myocardial infarction in early presenters using 1-hour delta of high sensitive Troponin I: a pilot study. [PDF]

open access: yesClinics (Sao Paulo)
Jeraiby MA   +10 more
europepmc   +1 more source

Nickel‐Catalyzed Three‐Component Difluoroalkylation‐Amination for the Direct Access to Anti‐Inflammatory β‐Difluoroalkyl Amines

open access: yesAdvanced Science, EarlyView.
A nickel‐catalyzed three‐component reductive fluoroalkylation‐amination strategy of N‐vinylamides for the direct access to the α‐amidyl‐β‐difluoroalkyl amines was reported here. The synthetic method features with broad substrate scope, mild conditions, high functional group tolerance, and convenience to handle.
Chang Xu   +8 more
wiley   +1 more source

Submucosal Colonic Endometriosis Presenting as a Sigmoid Polyp. [PDF]

open access: yesACG Case Rep J
Ahmed H   +3 more
europepmc   +1 more source

Developing Soft Interconnected Microchannel Network for 2D Skin‐Like Actuator

open access: yesAdvanced Science, EarlyView.
A soft interconnected network of microchannels is proposed to develop new pneumatic actuators for future bio‐inspired soft robots. Simultaneous stimulation of this network generates regional asymmetric strains in walls of microchannels whose interaction across the entire surface leads to bending curvatures in multidimensions.
John Noee   +4 more
wiley   +1 more source

An Avalanche Effect Nanomodulator Triggers Cascade Ferroptosis/Cuproptosis for Immunosuppressive Microenvironment Remodeling

open access: yesAdvanced Science, EarlyView.
A nanomodulator called L‐Arginine/lificiguat@Copper‐hollow Prussian blue@Calcium phosphate nanoparticles is constructed to launch a self‐amplifying “avalanche effect” in tumor cells. The ensuing cascade, triggered by the acidic tumor microenvironment and near‐infrared light, induces calcium overload, generates a reactive oxygen species and reactive ...
Hongmei Zhou   +9 more
wiley   +1 more source

Discriminative performance of non-invasive scoring systems for VCTE-defined steatosis and fibrosis in patients with psoriasis. [PDF]

open access: yesHepatol Forum
Yuksel S   +7 more
europepmc   +1 more source

A Site‐Aware Representation Learning Framework For Unified Molecular Interaction Modeling and Generative Design

open access: yesAdvanced Science, EarlyView.
MolDBG is a site‐aware, sequence‐only framework that unifies drug‐target affinity prediction, binding‐site identification, and affinity‐conditioned molecular generation for structured proteins. Guided by multi‐task binding‐site supervision, it aligns interaction‐critical residues before learning drug‐target representations and simultaneously infers ...
Gang Luo   +6 more
wiley   +1 more source

Bioethics and Medical Litigation in France: An Exploratory Study. [PDF]

open access: yesJ Eval Clin Pract
Nader R   +4 more
europepmc   +1 more source

Gut Microbiota‐Isoallolithocholic Acid Crosstalk Promotes Calcium Oxalate Kidney Stone Formation via PARP1‐Mediated Parthanatos

open access: yesAdvanced Science, EarlyView.
ABSTRACT Bile acids have been implicated in calcium oxalate (CaOx) nephrolithiasis. Here, we employ multi‐omics approaches to identify isoallolithocholic acid (isoalloLCA) as the key bile acid elevated in the feces, serum, kidney, and urine of CaOx rats, confirmed by spatial metabolomics.
Zijian Zhou   +9 more
wiley   +1 more source

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