Results 121 to 130 of about 16,231 (261)

Aberrant GRP78 Phase Transition Sustains Endothelial IRE1α Signaling and Drives Blood–Brain Barrier Failure in Cerebral Amyloid Angiopathy

Advanced Science, EarlyView.
Vascular Aβ40 corrupts GRP78 phase behavior in brain endothelial cells, sustaining IRE1α–TRAF2–JNK signaling and driving apoptosis, tight junction loss, and blood–brain barrier failure in cerebral amyloid angiopathy. Pharmacological IRE1α inhibition restores vascular integrity, reduces leakage, and improves functional outcomes, revealing a targetable ...
Honglin Zheng, Qiang Li, Haiyang Luo, Yapei Yuan, Na Zhang, Yongting Lu, Suying Duan, Jieshi Zhong, Hang Zhang, Chenyang Liu, Yaochong Zhang, Wenzhuo Zhao, Yaxuan Song, Tuo Wang, Si Yan, Yapeng Li, Han Liu, Yuan Gao, Zongping Xia, Yuming Xu   +19 more
wiley   +1 more source

External validation of the REDUCTION clinical decision aids for ruling out fractures in patients with midfacial and mandibular injuries in the emergency department: a protocol for a prospective multi-centre cohort study. [PDF]

Scand J Trauma Resusc Emerg Med
van der Zaag PD, Rozema R, Reininga IHF, van Minnen B.   +3 more
europepmc   +1 more source

N–O Dual Functional Group Transposition via Energy Transfer Photocatalysis

Advanced Science, EarlyView.
N–O dual functional group transposition (dFGT) enabled by the photocatalytic energy transfer (EnT) has been developed. This methodology is applicable to both activated and unactivated alkyl derivatives for dFGT, and it also successfully extended to N–N dFGT, demonstrating its general applicability.
Lei Bao, Xueyu Wang, Yang Zhou, Beibei Zhan, Xiaheng Zhang   +4 more
wiley   +1 more source

Validation of Multi-Target Stool DNA Methylation Test for Colorectal Cancer Detection: A Preliminary Analysis. [PDF]

Biomedicines
Abdul Rahman KA, Mohammad Azmi N, Abdullah Suhaimi SN, Mohd Azman ZA, Raduan F, Muhammad Nawawi KN, Shah SA, Tan GC, Wong YP, Abdul Raub SH.   +9 more
europepmc   +1 more source

The Plant‐to‐Plant Circular Strategy: Coupling Photodegradation and Phytoremediation With Plant‐Based Nanomaterials for Plastic Degradation

Advanced Science, EarlyView.
Plant‐based nanomaterials derived from alfalfa serve as dual‐function catalysts, coupling photodegradation and phytoremediation to degrade polyethylene under UV‐A light and in soil. The nanomaterials work synergistically with alfalfa and soil microbes, achieving efficient plastic breakdown without trophic transfer.
Haoran Liu, Lena Ciric, Yuheng Wang, Ziru Pei, Manpreet Bhatti   +4 more
wiley   +1 more source

Preliminary Rulings in The Civil Procedure

, 2015
This article explores the subject of preliminary rulings in the Chilean Civil Procedure. Namely, it is focused on those issues which, due to their logical and legal connection to the object of the process, must be decided by the same or a different Court, before the final and substantial judgement is made.
openaire   +1 more source

Development of a Hybrid Cervical Spine Clearance Algorithm in Trauma: Tackling the Challenges of the NEXUS Criteria and Canadian Cervical Spine Rule Utilization in a Low-Volume Tertiary Neuroscience Unit. [PDF]

Cureus
Ajah HE, Nzekwu OO.
europepmc   +1 more source

Nickel‐Catalyzed Three‐Component Difluoroalkylation‐Amination for the Direct Access to Anti‐Inflammatory β‐Difluoroalkyl Amines

Advanced Science, EarlyView.
A nickel‐catalyzed three‐component reductive fluoroalkylation‐amination strategy of N‐vinylamides for the direct access to the α‐amidyl‐β‐difluoroalkyl amines was reported here. The synthetic method features with broad substrate scope, mild conditions, high functional group tolerance, and convenience to handle.
Chang Xu, Fangting Ma, Fan Ding, Luyan Wang, Yunxi Li, Yunzhi He, Xingang Zhang, Siyu He, Dandan Liu   +8 more
wiley   +1 more source

Assessment of sexual function and its association with quality of life and disease severity in patients with atopic dermatitis. [PDF]

An Bras Dermatol
Bressan A, Troncoso N, Machado CJ, Cortez de Almeida RF, Carneiro S.   +4 more
europepmc   +1 more source

Enhancing Electrical Impedance Based Deformation Sensing with Dielectric Current Guide

Advanced Electronic Materials, EarlyView.
This work introduces a dielectric‐based field manipulation strategy for electrical impedance tomography in soft robotics. By using silicone as a passive electric field guide, improved deformation sensing accuracy and reduced interference are achieved without embedding conductive components.
Arsen Abdulali, David Hardman, Yue Xie, Fumiya Iida   +3 more
wiley   +1 more source