Results 81 to 90 of about 1,867 (299)

Malectin Alleviates Endoplasmic Reticulum Stress in Gestational Diabetes Mellitus via Glycoprotein Quality Control Mechanisms

Advanced Science, EarlyView.
Malectin alleviates high glucose‐induced ER stress and damage in placental trophoblasts, a function dependent on its six critical carbohydrate‐binding residues. In a GDM mouse model, administration of TAT‐Malectin ameliorated hyperglycemia and placental ER stress and prevented fetal macrosomia.
Jiahui Zhu, Yumeng Zhang, Ye Wang, Xiaoyu Zhu, Ailin Yuan, Weijing Yin, Huangmin Yu, Xuemin Pang, Yufeng He, Yuchen Wang, Tong Wang, Yong Li, Yunlong Si   +12 more
wiley   +1 more source

Advance Tax Rulings in Perspective: A Theoretical and Comparative Analysis

, 2014
Advance tax rulings are an increasingly common feature of mature income tax systems throughout the world. The Organisation for Economic Co-operation and Development’s (OECD’s) work demonstrates that there has been a trend from 1990 to 2013 among OECD ...
Alarie, Benjamin, Datt, Kalman H., Weeks, Greg, Sawyer, Adrian J.   +3 more
core   +1 more source

The impact of EU expansion on the Preliminary Rulings Procedure

, 2008
In CILFIT (case 283/81), the European Court of Justice (ECJ) endorsed the use of the acte clair doctrine – the notion that national courts of “last resort” may decide to refrain from seeking a preliminary ruling under Article 234 (3) EC.
Storey, Tony
core  

Gut Mycobiota‐Associated Tryptophan Catabolites Protect Against Metabolic Dysfunction‐Associated Steatotic Liver Disease

Advanced Science, EarlyView.
ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao, Shuangya Fan, Juan Xu, Zhen Xu, Chen Peng, Junxing Qu, Ziqian Bing, Shizhen Zhou, Sunan Shen, Guifang Xu, Yue Zhao, Tingting Wang   +11 more
wiley   +1 more source

Maritime Rule of Law: Some Preliminaries

Hague Journal on the Rule of Law, 2023
AbstractCan there be rule of law at sea? In extending the traditionally terrene ideal seaward, there are a range of conceptual difficulties. These difficulties are outlined, and a recurring thought pattern is set out that is found in the traditions of thought about the rule of law as protecting members of a community from the abuse of power. Drawing on
openaire   +1 more source

Cuestiones prejudiciales en la Unión Europea y consultas prejudiciales en la Comunidad Andina: Similitudes, diferencias e influencias

Revista Electrónica de Estudios Internacionales, 2013
The objective of this research is to compare the legal regime of the European Union preliminary ruling procedure and the Andean Community preliminary consultation procedure.
Manuel Cienfuegos Mateo
doaj  

Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

Advanced Science, EarlyView.
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao, Lifang Guo, Guochao Yang, Chaoli Huang, He Wang, Jian‐Jun Yang, Guiquan Chen, Yimin Hu   +7 more
wiley   +1 more source

What Happens After the Court of Justice Has Given its Ruling? Promises and Pitfalls of Strategic Litigation Against Internal Border Controls in EU Law

German Law Journal
This Article inquires into the aftermath of judgments by the CJEU under the preliminary ruling procedure under article 267 TFEU in cases of strategic litigation. As the principal objective of strategic litigants is to effectively achieve broader societal,
Stefan Salomon
doaj   +1 more source

Economic and Political Considerations of the Court’s Case Law Post Crisis: An Example from Tax Law and the Internal Market

Croatian Yearbook of European Law and Policy, 2013
This paper investigates whether the ‘Euro crisis’ has altered the Court of Justice’s legal reasoning in the area of the four freedoms and direct taxation.
Katerina Pantazatou
doaj   +1 more source

The possibilities of the General Court of the European Union to give preliminary rulings

, 2023
Vairāk kā divdesmit gadus pastāv iespēja piešķirt Eiropas Savienības Vispārējai tiesai kompetenci sniegt prejudiciālus nolēmumus. Jautājums par šādas kompetences nodošanu Vispārējai tiesai vairākkārt ir bijis darba kārtībā, tomēr reālas izmaiņas nav ...
Ķelle, Megija
core