Results 91 to 100 of about 622 (231)

Bioinspired Passive Flow Routing to Mitigate Thrombosis in Prosthetic Heart Valves and Cardiovascular Devices

Advanced Science, EarlyView.
Bioinspired passive flow routing mitigates thrombosis in cardiovascular devices by redirecting a small fraction of forward flow into stagnation‐prone regions. Inspired by avian alula and aircraft slat mechanisms, strategically placed routing channels restore washout around mechanical heart valves, reducing low‐shear exposure by four orders of magnitude
Yevgeniy Kreinin, Mark Epshtein, Yahel Talmon, Tirosh Mekler, Itay Or, Mahli Raad, Gil Bolotin, Josué Sznitman, Netanel Korin   +8 more
wiley   +1 more source

Deep Learning Network‐Tailored Microenvironment Matching of 4D Bioprinting Bioactive Scaffolds for Bone Regeneration

Advanced Science, EarlyView.
A DLN dataset was built to analyze MABS composition versus in vitro/in vivo osteogenesis and angiogenesis. An MLP neural network, taking BG morphological parameters as input, extracts bioactive features from these datasets. A rabbit tibial defect model then validates 4D‐printed MABS for adaptability and bone regeneration in critical defects.
Xiongjie Liang, Yuechi Zhang, Weifeng Hu, Shiyan Lv, Fan Jia, Yan Zhang, Feng Wu, Changjiang Yang, Guanqi Zhen, Jinglong Yan, Xu Cui, Wei Zhao, Guanghua Chen   +12 more
wiley   +1 more source

Chiral Plasmonic Printing of Discrete Hierarchical Chiral Au@Chiral Ag Semi‐Core‐Shell Nanorods With Chiral Plasmon‐Enhanced Photocatalysis

Advanced Science, EarlyView.
Chiral plasmonic printing uses CPL as a chiral stimulus to guide asymmetric Ag deposition on chiral Au NRs seeds. Under CPL, hot carriers reduce Ag+, and the process is controlled by both the CPL handedness and the chiral SPR. L‐dc Au generates more hot electrons under LCP than RCP, while D‐dc Au shows the opposite, revealing chiral photon‐selective ...
Yaxin Cao, Haoyu Li, Mengli Wu, Shengshi Fan, Shenli Wang, Haibo Zhou, Guangchao Zheng   +6 more
wiley   +1 more source

A Generative Neuro‐Symbolic AI for Protein Sequence Design

Advanced Science, EarlyView.
We introduce EffieDes, a neuro‐symbolic framework coupling deep learning‐based fitness landscape parameterization with exact automated reasoning. Unlike greedy sampling, EffieDes identifies sequences that globally optimize fitness while satisfying intricate design constraints.
Marianne Defresne, Delphine Dessaux, Samuel Buchet, Lucie Barthe, Liza Ammar‐Khodja, Bessam Azizi, Valentin Durante, Gianluca Cioci, Simon de Givry, Alain Roussel, Luis F. Garcia‐Alles, Thomas Schiex, Sophie Barbe   +12 more
wiley   +1 more source

China's criminal incidental civil public interest litigation in food safety: practice review and pathways to improvement. [PDF]

Front Nutr
Han X, Li B.
europepmc   +1 more source

A Spatially Directed Microneedle Patch Enables Intratumoral Co‐Delivery of FOLFIRINOX, Surufatinib, and Anti‐PD‐1 for Chemo‐Immunotherapy of Pancreatic Ductal Adenocarcinoma

Advanced Science, EarlyView.
A double‐layered shell‐core microneedle patch is developed to co‐deliver FOLFIRINOX, surufatinib, and anti‐PD‐1 for localized chemo‐immunotherapy of PDAC. This strategy achieves sustained tumor suppression, reduces metastasis, and reprograms the TME by enhancing CD8+ T‐cell infiltration and inhibiting Tregs and M2 macrophages infiltration, while ...
Tingting Kong, Ximo Xu, Xiao Zhang, Chuntao Wu, Zhengjun Qiu, Beiyuan Hu, Zihao Qi, Qiang Tian, Yuqin Yang, Hanguang Dong, Fei Wu, Tuo Jin, Yan Zheng, Jiang Long   +13 more
wiley   +1 more source

Legislation on Medical Assistance in Dying (MAID): Preliminary Consideration on the First Regional Law in Italy. [PDF]

Healthcare (Basel)
Blandi L, Tolentino R, Basile G, Tronconi LP, Signorelli C, Bolcato V.   +5 more
europepmc   +1 more source

Time Resolved DNA Barcodes for Information Encoding and Dynamic Encryption

Advanced Science, EarlyView.
This study establishes a molecular information platform based on DNA Temporal Barcodes. Information is encoded through combinations of DNA tags with distinct retention times, while dynamic encryption is achieved through a key‐triggered DNA ligation.
Likang Chu, Haixia Wang, Haiyan Gao, Sixian Chen, Zilong Li, Zhanyihao Hao, Lei He, Da Han   +7 more
wiley   +1 more source

The night is dark and full of hesitation. The latest step in the legal trajectory of assisted suicide in Italy: through tentative judicial openings, bioethical contradictions and the Parliament's deafness. [PDF]

Front Pharmacol
Frati P, Albore M, Ertola EM, Del Prete S, Sorace L, La Russa R, Bolino G.   +6 more
europepmc   +1 more source

The persistence of legal uncertainty on EU citizens' access to social benefits in Germany. [PDF]

J Eur Soc Policy, 2022
Gago A, Hruschka C.
europepmc   +1 more source