Results 51 to 60 of about 56,479 (241)
We describe a microfluidic tumor‐stroma co‐culture model, engineered to resist collagen‐hydrogel contraction driven by fibroblast activity. Surface silanization with APTES covalently anchors the matrix to the chip, while Genipin crosslinking progressively increases stiffness and elasticity without harming cells. This supports >10 days of co‐culture and
Doriane Le Manach +4 more
wiley +1 more source
A two‐phase workflow (OFAT screening followed by central composite design) maps how processing variables tune PFCE‐PLGA nanoparticle size, dispersity, surface charge, loading, and 19F‐MRI signal. In situ, time‐resolved synchrotron SAXS tracks albumin‐corona growth on intact dispersions and reveals PFCE‐dependent adsorption pathways.
Joice Maria Joseph +11 more
wiley +1 more source
The Limitation of Intellectual Property in the Name of Competition [PDF]
Intellectual property (“IP”) is often credited with providing an incentive for inventors to develop their creativity. Through IP protection, inventors can recoup their investment and make a profit.
Nihoul, Paul
core +1 more source
Is Toufik Lounes another brick in the wall? The CJEU and the on-going shaping of the EU citizenship [PDF]
This Insight tackles a recent judgment of the CJEU, Toufik Lounes (Court of Justice, judgment of 14 November 2017, case C-165/16, Toufik Lounes v. Secretary of State for the Home Department), where the CJEU was asked to rule on the case of a EU national,
Gualco, Elena
core +2 more sources
Plasmonic Enhancement of Fluorescence and Protein Dynamics in Living Mammalian Cells
This study demonstrates plasmonic enhancement of the function of fluorescent voltage sensing proteins (genetically encoded voltage indicators, (GEVIs), QuasAr6) in live mammalian cells. Coupling to plasmonic nanoparticles does not just increase fluorescence, but influences the protein photocycle, creating a hybrid sensor with its response speed to ...
Marco Locarno +16 more
wiley +1 more source
Maybe Definitely – Definitely Maybe? EC Competition Law – Is the Time Ripe for Reform? [PDF]
[Summary]. The aim of this article is to discuss whether the timing for the Commission’s Proposal for reforming the implementation of Articles 81 and 82 of the EC Treaty is appropriate based on legal certainty considerations.
Goldschmidt, Peter I. B. +1 more
core
Highly water‐soluble dicationic bis(indolium) dyes have been prepared, showing excellent two‐photon absorption and light emission. Their fluorescence behavior discloses an unusual increasing blue shift with increasing solvent polarity, which, in parallel, is beneficial for enhanced detection in biological media.
Carlos Benitez‐Martin +5 more
wiley +1 more source
The Constitutional Regulation of Forensic Evidence [PDF]
The Constitution increasingly regulates the use of forensic evidence in criminal cases. This is a remarkable shift. In decades past, the U.S. Supreme Court declined to provide strong due process protection against destruction of forensic evidence or to ...
Garrett, Brandon L.
core +1 more source
A nano‐interception strategy disrupts pathogenic fibroblast–macrophage crosstalk in chronic heart failure. Scalable Prussian blue nanoparticles selectively sequester CCL2 via ultrahigh‐affinity binding, preventing CCR2+ macrophage recruitment and breaking a key fibro‐inflammatory circuit. This approach demonstrates robust efficacy in murine and porcine
Bo Chen +16 more
wiley +1 more source
An overview of design principles and scalable fabrication strategies for multifunctional bio‐based packaging. Radiative cooling films, modified‐atmosphere films/membranes, active antimicrobial/antioxidant platforms, intelligent optical/electrochemical labels, and superhydrophobic surfaces are co‐engineered from material chemistry to mesoscale structure
Lei Zhang +6 more
wiley +1 more source

