Results 41 to 50 of about 6,952 (262)

Continuum Mechanics Modeling of Flexible Spring Joints in Surgical Robots

Advanced Robotics Research, EarlyView.
A new mechanical model of a tendon‐actuated helical extension spring joint in surgical robots is built using Cosserat rod theory. The model can implicitly handle the unknown contacts between adjacent coils and numerically predict spring shapes from straight to significantly bent under actuation forces.
Botian Sun, Liang Zhang, Jianwen Zeng, Xuefeng Wang   +3 more
wiley   +1 more source

Tumbling Magnetic Microrobots for Targeted In Vivo Drug Delivery in the GI Tract

Advanced Robotics Research, EarlyView.
We introduce a microrobot design and integrated system for on‐demand targeted drug release in the gastrointestinal tract. The microrobot has an embedded magnet for actuation with external magnetic fields and is visualized in real time using ultrasound. It has two drug release ports sealed with a thermally sensitive wax. Local heating of the wax using a
Aaron C. Davis, Luis Carlos Sanjuan Acosta, Shubh P. Mehta, Baiyan Qi, Yang Yang, Luis Solorio, Craig J. Goergen, David J. Cappelleri   +7 more
wiley   +1 more source

Engineering Immunoregenerative Therapy via an Immunomodulatory Binary Pharmacology Hydrogel Depot for Prolonged Allograft Survival

Advanced Science, EarlyView.
An immunomodulatory hydrogel (iGEL) forms spontaneously upon subcutaneous injection, acting as a tissue‐adhesive depot. It releases anti‐rejection and regenerative agents in response to inflammation, suppressing T‐cell activity, promoting vascular repair, and restoring allograft function without systemic immunosuppression.
Ning Wang, Ruiqi Sun, Yang Fu, Zhonghan Wu, Xinyu Tong, Hong Tang, Wentao Zhao, Zhi Liang, Jintao Zheng, Yanan Guan, Ke Zhou, Penghong Song, Shusen Zheng, Hangxiang Wang, Haiyang Xie   +14 more
wiley   +1 more source

Finite Element Study of Vacuum Preloading and Prefabricated Vertical Drains Behavior for Soft Soil Improvement [PDF]

Jurnal Teknik Sipil, 2019
Finite element modeling of soft soil improvement with vacuum preloading and prefabricated vertical drains (PVD) behavior was carried out by considering smear effect and equivalent plane strain based on permeability conversion.
Dedi Apriadi, Ressa Adrian Bernessa, Nisrina Aulia Is Marsa   +2 more
doaj   +1 more source

Astrocytic Phenotypic Switching in Posterior Piriform Cortex Orchestrates Bone Cancer Pain–Depression Comorbidity via Purinergic–Noradrenergic Signaling

Advanced Science, EarlyView.
Bone cancer pain and depression share a common origin: astrocytic A2‐to‐A1 transition in the posterior piriform cortex. This phenotypic shift disrupts the ATP–adenosine–A2AR–norepinephrine axis, simultaneously driving nociceptive and affective dysfunction.
Jiang‐Ping Liu, Jun‐Han Zhang, Zhi‐Xuan Tan, Wei‐Bing Yan, Ya‐Ru Yuan, Yao Liu, Bing‐Di Wei, Meng‐Qi Ding, Zhuo‐Min Fu, Ying Liu, An‐Qi Wang, Lin Ma, Yong‐Hong Li, Er‐Qing Chai, Chao‐Jun Wei   +14 more
wiley   +1 more source

Effect of preoperative oxytocin infusion on haemodynamics among women undergoing elective caesarean section under spinal anaesthesia: A randomised controlled study

Indian Journal of Anaesthesia
Background and Aims: Various strategies to improve haemodynamics to avoid hypotension following spinal anaesthesia for caesarean section are reported. Uterine contractions induced with oxytocin lead to autotransfusion that may aid in maintaining blood ...
Ram Jeevan, Pankaj Kundra, Sandeep Mishra, Dilip Kumar Maurya, Anish Keepanasseril   +4 more
doaj   +1 more source

Discussion on Reinforcement Mechanism and Construction Technology of Pressurized Vacuum Preloading [PDF]

E3S Web of Conferences, 2019
Based on the basic theory of vacuum preloading, this paper proposes an good effect of pressurized vacuum preloading in which the high pressure gas results in tiny cracks between the air pressurized pipe and band drain. Therefore additional drainage paths
Ai-jun ZHUGE
doaj   +1 more source

Cyclic Mechanical Loading of Cardiomyocytes via Pressure‐Driven Non‐Planar Membrane Deformation in a Bioreactor System

Advanced Science, EarlyView.
In this research article, Mansoor and coworkers present a novel device that applies controlled mechanical stimuli to cardiomyocytes using pressure‐driven membrane deformation. By exposing cells to physiologically and pathologically relevant loading conditions, the platform reproduces distinct structural, functional and molecular responses associated ...
Haris Mansoor, Gabrielle Juul, Jil Patel, Heran Pradhan, Gram Hepner, Jackson Jewell, Mark Bardin, Ryan Slusser, Abigail Glezer, Leda Klouda, Melikhan Tanyeri, Anita Saraf   +11 more
wiley   +1 more source

Causes of Ground Settlements in Upper Reservoir of Hydro-Wind Plant of El Hierro and Method Implemented for Soil Improvement

Proceedings, 2018
This article exposes one of the main engineering problems in the design and construction of the upper reservoir of El Hierro hydro-wind plant, relative to the high settlement of the bottom in the southeast area.
Fabiola Fernández-Baniela, Daniel Arias, Álvaro Rubio-Ordoñez   +2 more
doaj   +1 more source

Effect of inelastic multiaxial preloading on high cycle fatigue strength

Nihon Kikai Gakkai ronbunshu, 2020
This study investigates an effect of inelastic non-proportional preloading on failure life in a followed high cycle fatigue for two steels, SUS316 stainless and Mod.9Cr-1Mo steels.
Takahiro MORISHITA, Takamoto ITOH, Naoto KASAHARA   +2 more
doaj   +1 more source