Application of GUHA data mining method in cohort data to explore paths associated with premature death: a 29-year follow-up study. [PDF]
Nosraty L+5 more
europepmc +1 more source
Congruent and Oriented Crystallization of Mixed Sn–Pb Perovskite From the Nano‐ to Centimeter Scale
A Lewis‐base ligand trimethylthiourea preferentially coordinates to Sn2+ over Pb2+ and regulates the crystallization kinetics of FASn0.5Pb0.5SnI3. The resulting films consist of nearly stoichiometric unit cells and micrometer‐sized crystal grains exposing their (100) face.
Donghao Miao+10 more
wiley +1 more source
County-level association between modifiable health behaviors and premature mortality in the United States. [PDF]
Minhas AMK+8 more
europepmc +1 more source
This study reveals a novel crosstalk between hepatic SREBP2‐mediated cholesterol biosynthesis pathway and peripheral lipoprotein lipase‐mediated lipolysis pathway in the regulation of systemic lipid metabolism. Notably, the lipid‐lowering effects of SREBP2 inhibition are independent of a functional LDL receptor, highlighting the potential of acute ...
Yifan Wang+13 more
wiley +1 more source
Logistic regression analysis of risk factors for Respiratory Distress Syndrome in Late Preterm Infants. [PDF]
Zhu H+5 more
europepmc +1 more source
This study indicates that perinatal antibiotic exposure elevates susceptibility to high‐fat‐diet‐induced hepatic lipid accumulation via disrupting early‐life gut microbiota colonization. The decreased Lactobacillus colonization inhibits primary‐to‐secondary bile acid conversion, lowering secondary bile acids, enhancing adulthood intestinal lipid ...
Yan‐Yan Zhu+11 more
wiley +1 more source
Editorial: Recent advances in our understanding of NEC pathogenesis, diagnosis, and treatment - volume II. [PDF]
Yan X, Khashu M.
europepmc +1 more source
Histone Deacetylase 6 (HDAC6) in Ciliopathies: Emerging Insights and Therapeutic Implications
HDAC6 regulates primary cilia, crucial for cellular signalling and environmental responses. Dysregulation of HDAC6 contributes to ciliopathies, affecting multiple organs. This review examines HDAC6's role in ciliogenesis, its interaction with signaling molecules, and its potential as a therapeutic target.
Zhiyi Wang+5 more
wiley +1 more source
As a plant‐derived flavonoid, apigenin directly targets PRDX6 to inhibit its PLA2 activity, blocking HSPA8 activation and disturbing its interactions with ATM and p38MAPK in senescent cells. By dampening wide spectrum expression of the SASP, apigenin prevents loss of tissue homeostasis, improves organ function, and alleviates multiple age‐related ...
Hongwei Zhang+10 more
wiley +1 more source
Fourth UNHLM on noncommunicable diseases 2025: An opportunity to bridge the transcending priorities for impact in global south. [PDF]
Varghese C+4 more
europepmc +1 more source