Results 291 to 300 of about 214,960 (327)

ERCC1 mice, unlike other premature aging models, display accelerated epigenetic age

, 2022
Perez K, Parras A, Rechsteiner C, Haghani A, Brooke R, Mrabti C, Schonfeldt L, Horvath S, Ocampo A.   +8 more
europepmc   +1 more source

Long‐Term Safety and Efficacy of Mepolizumab in Eosinophilic Granulomatosis With Polyangiitis

Arthritis &Rheumatology, EarlyView.
Objective Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare, relapsing, inflammatory disease. Management of EGPA predominantly relies on oral corticosteroids (OCS), which are associated with many adverse effects. The phase 3 MIRRA trial demonstrated efficacy and safety of mepolizumab, anti‐interleukin‐5 biologic, for EGPA.
Michael E. Wechsler, Jared Silver, Gerhard Wolff, Robert G. Price, Rejina Verghis, Peter F. Weller, Peter A. Merkel, Paneez Khoury, on behalf of the EGPA Mepolizumab Open‐Label Extension study group, Arnaud Bourdin, Pascal Chanez, Anoop Chauhan, Vincent Cottin, Gerald Gleich, Berhnard Hellmich, Tomonori Ishii, David Jayne, Jean‐Emmanuel Kahn, Peter Kern, Nader Khalidi, Ina Koetter, Carol Langford, Amy Markezich, Paul Monach, Shamsa Naveed, Peter Oelzner, Kenneth Pinna, Xavier Puechal, Emory H. Robinette, Florence Roufosse, Reinhard Voll, Andrew Schafer, Kaharu Sumino, Masami Taniguchi, Phillip Lieberman   +34 more
wiley   +1 more source

Triethylene Glycol Squalene Improves Hair Regeneration by Maintaining the Inductive Capacity of Human Dermal Papilla Cells and Preventing Premature Aging. [PDF]

ACS Pharmacol Transl Sci
Bejaoui M, Oliva Mizushima AK, Ngoc Linh T, Arimura T, Tominaga K, Isoda H.   +5 more
europepmc   +1 more source

Efficacy and safety of dotinurad versus febuxostat for the treatment of gout: a randomised, multicentre, double‐blind, phase 3 trial in China

Arthritis &Rheumatology, Accepted Article.
Objectives Dotinurad is a selective urate reabsorption inhibitor that reduces serum urate levels. We compared the efficacy and safety of dotinurad with febuxostat in Chinese patients with gout. Methods This phase 3, multicentre, randomised, double‐blind, parallel‐group study randomly allocated (1:1) eligible patients with gout to receive oral dotinurad
Jia Sun, Yu Wang, Yongjing Cheng, Dongmei Guo, Jiankang Hu, Dongzhou Liu, Zhengnan Gao, Changgui Li, Yibing Lu, Xiaodan Kong, Yu Liu, Zhenyu Jiang, Bin Yi, Hongfeng Zhang, Baijie Xu, Shihao Yu, Rieko Kokan, Kohei Ishikawa, Mikiko Kawakatsu, Zhuoli Zhang   +19 more
wiley   +1 more source

Clinical impact of multiparametric contrast‐enhanced dual‐energy computed tomography in arthritis imaging – a prospective single‐center study

Arthritis &Rheumatology, Accepted Article.
Objectives To evaluate the influence of contrast‐enhanced dual‐energy CT (CE‐DECT) in detecting and differentiating rheumatic joint diseases of the hand. Methods In this prospective study, patients with suspected arthritis of the hand were investigated consecutively alongside the standard clinical procedure.
Sevtap Tugce Ulas, Jürgen Mews, Sarah Ohrndorf, Robert Biesen, Katharina Ziegeler, Edgar Wiebe, Fabian Proft, Udo Schneider, Denis Poddubnyy, Torsten Diekhoff   +9 more
wiley   +1 more source

Pregnancy outcomes in women with systemic sclerosis before and/or after diagnosis, and by parity ‐ A Swedish population‐based cohort study

Arthritis &Rheumatology, Accepted Article.
Objective To assess risks of adverse pregnancy outcomes (APO) in a contemporary cohort of women with systemic sclerosis (SSc) in relation to the timing of SSc diagnosis and by parity. Methods From the nationwide Swedish Medical Birth Register, we assembled pregnancies with births in women with SSc and in comparator women from the general population ...
Weng Ian Che, Luigi Annicchiarico, Laura Andreoli, Olof Stephansson, Marie Holmqvist, Karin Hellgren   +5 more
wiley   +1 more source

Plant Foods Intake and Risk of Premature Aging in Adult Survivors of Childhood Cancer in the St Jude Lifetime Cohort (SJLIFE). [PDF]

J Clin Oncol
Wang M, Lan T, Williams AM, Ehrhardt MJ, Lanctot JQ, Jiang S, Krull KR, Armstrong GT, Hudson MM, Colditz GA, Robison LL, Ness KK, Park Y.   +12 more
europepmc   +1 more source

The Value Chain of Sustainable Dual Carbon Sodium Ion Capacitors

Batteries &Supercaps, EarlyView.
Sodium‐ion capacitors (SICs) bridge the energy‐power gap between batteries and supercapacitors, offering sustainable and scalable energy storage solutions. This review provides a 360‐degree perspective on SIC technology, covering material choices, presodiation strategies, manufacturing challenges, applications and life cycle assessment to ensure ...
Roman Mysyk, Daniel Carriazo, Damien Saurel, Maria Arnaiz, Olivier Crosnier, Thierry Brousse, Kangkang Ge, Pierre‐Louis Taberna, Patrice Simon, Sander Ratso, Einar Karu, Alberto Varzi, Juan Pablo Badillo, Andrea Hainthaler, Akshaya Sidharthan, Andrea Balducci, Obinna Egwu Eleri, Amaia Saenz de Buruaga, Javier Olarte, Juan Dayron Lopez Cardona, Fatemeh Bahmei, Sebastian P. Bautista, Marcel Weil, Jon Ajuria   +23 more
wiley   +1 more source

RETRACTION: Mechanism of Zuogui Pill Enhancing Ovarian Function and Skin Elastic Repair in Premature Aging Rats Based on Artificial Intelligence Medical Image Analysis. [PDF]

Skin Res Technol
europepmc   +1 more source

Mechanism of Zuogui pill enhancing ovarian function and skin elastic repair in premature aging rats based on artificial intelligence medical image analysis.

Skin Res Technol
Zhang X, Wang F, Zhu X, Xu L, Qin L, Xu W, Fan B.   +6 more
europepmc   +1 more source