Results 241 to 250 of about 163,537 (314)

Biallelic Truncating Variants in SCN3B Encoding Nav Channel Subunit β3 Lead to Neurodevelopmental Phenotype with and without Epilepsy and Ataxia

Annals of Neurology, EarlyView.
SCN3B encodes the β3 auxiliary subunit, essential for voltage‐gated Na+ (Nav) channel trafficking and gating. Although SCN3B has been associated with cardiac disorders, a link with neurodevelopmental disorders (NDD) has not been established. Using a genotype‐first approach, we identified homozygous truncating variants (c.281G>A‐β3W94*, c.584 + 1G>A ...
Nathan Routledge, Maxime Lammens, Reza Maroofian, Bakht Beland, David Murphy, Asif Mir, Zia Ullah, Javeria Reza Alvi, Tipu Sultan, Stephanie Efthymiou, Frank Bosmans, Henry Houlden   +11 more
wiley   +1 more source

Development and validation of a self-management self-efficacy scale for premature birth prevention (SMSE-PBP) for women of childbearing age. [PDF]

BMC Womens Health
Kim SH, Lee YJ.
europepmc   +1 more source

Approaches to Enhance Photodynamic Therapy of Lung Cancer: Potential Application of Nanoparticles

Advanced NanoBiomed Research, EarlyView.
Bioactive ligand‐targeted nanocarriers can accommodate functionalization with numerous targeting ligands for effective delivery of photosensitizers (PSs) within targeted photodynamic therapy. Various targeting moieties including peptides, antibodies, carbohydrates, aptamers, proteins, and PS anticancer molecules can be attached to nanomaterials.
Nokuphila Winifred Nompumelelo Simelane, Heidi Abrahamse   +1 more
wiley   +1 more source

Optoregulated mRNA Delivery Controls Pleiotropic Immune Signaling for Tumor‐Targeted Therapy

Angewandte Chemie, EarlyView.
A light‐induced transfection system (LITS) was designed to precisely control the delivery of mRNA, achieving spatiotemporal de‐coupling of the pleotropic inflammatory and tolerogenic signals of interleukin‐2 to conduct safe eradication of tumors. Abstract Spatiotemporal control of protein expression remains a critical challenge in messenger RNA (mRNA ...
Pengwen Chen, Guanghao Hu, Yuki Nakashima, Zhining Xu, Takayoshi Watanabe, Soichiro Kondo, Ervin Kovács, Horacio Cabral   +7 more
wiley   +2 more sources

Endogenously Triggered DNAzyme‐Based Nanostructures for Gene‐Combined Therapy

Advanced NanoBiomed Research, EarlyView.
DNAzymes show great promise for gene regulation and therapeutic use via controlled release triggered by endogenous factors. This review summarizes recent advances in designing and constructing nanoscale platforms enabling endogenously triggered release of DNAzyme.
Theoneste Muyizere, Julien Milon Essola, Eric Nyirimigabo, Janvier Mukiza, Jean Felix Mukerabigwi   +4 more
wiley   +1 more source

Emerging Strategies for Platelet‐Modified Nanoparticles in Targeted Tumor Therapy

Advanced NanoBiomed Research, EarlyView.
This review highlights innovative strategies using platelet‐modified nanoparticles to target tumors more precisely. By mimicking platelet functions, these biomimetic carriers improve tumor homing, enhance drug delivery, and reduce immune clearance.
Chunyu Bai, Lan Sun, Yimin Cui, Huan Meng, Jiulong Li, Qian Xiang   +5 more
wiley   +1 more source

Examining the Effectiveness of Interactive Webtoons for Premature Birth Prevention: Protocol for a Randomized Controlled Trial.

JMIR Res Protoc
Kim SH, De Gagne JC.
europepmc   +1 more source

Gypsum Gardens: Self‐Assembled Tubular Structures of Calcium Sulfate with Relevance for the Detection of Extraterrestrial Life

Angewandte Chemie International Edition, EarlyView.
Chemical gardens are self‐assembled architectures with “life‐like” morphologies that form in the absence of any biological activity. Here we show that such structures can also be obtained by contacting reservoirs of calcium and sulfate ions, under conditions that plausibly emulate those prevailing on early Mars.
Selina Reigl, Elisabeth Wagner, Carlos Pimentel, Werner Kunz, Alexander E. S. Van Driessche, Matthias Kellermeier   +5 more
wiley   +1 more source

Sustainable Active Packaging Films From PLA and PBAT With Thyme Oil: Extending the Shelf Life of Cherry Tomatoes

Journal of Applied Polymer Science, EarlyView.
Preparation of Sustainable PLA/PBAT Films with Thyme Oil for Active Packaging. ABSTRACT This study aimed to develop antimicrobial and biodegradable packaging films with excellent printability, designed to preserve the freshness of cherry tomatoes, using polylactic acid (PLA), polybutylene adipate terephthalate (PBAT), and natural thyme oil.
Celal Alpdogan, Hatice Birtane, Arzu Cagrı Mehmetoglu, Yalçın Kaya, Aslı Beyler Cigil, Türkün Sahinbaskan   +5 more
wiley   +1 more source