Results 311 to 320 of about 411,003 (365)

Populations Addressed in Vaccines Approved via the European Medicines Agency

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Therapeutic and prophylactic agents require robust evidence before patient use. Randomized controlled trials are essential for evaluating safety and efficacy but often exclude specific populations that are also targets for the intervention. This study assessed which populations are included in vaccine registration studies and/or addressed in label ...
Débora D. Gräf   +3 more
wiley   +1 more source

Rerouting Surgery of Cardiac Type Total Anomalous Pulmonary Venous Return in a Premature Newborn with Very Low Birth Weight

open access: bronze, 2007
En‐Ting Wu   +4 more
openalex   +1 more source

Gels for CO2 geo‐storage and conformance control: A systemic review of behavior and performance

open access: yesDeep Underground Science and Engineering, EarlyView.
This review provides a systemic evaluation of potential sealants used in CO2 subsurface storage practices. Critical analyses of how external factors like CO2, pH, brine salinity and hardness, rock mineralogy, pressure, temperature, and injectivity could affect the performance of different sealants are provided. Abstract Carbon capture and storage (CCS)
Funsho Afolabi   +6 more
wiley   +1 more source

The role of the PTHrP/Ihh feedback loop in the unusual growth plate location in mammalian metatarsals and pisiforms

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Longitudinal skeletal growth takes place in the cartilaginous growth plates. While growth plates are found at either end of conventional long bones, they occur at a variety of locations in the mammalian skeleton. For example, the metacarpals and metatarsals (MT) in the hands and feet form only a single growth plate at one end, and ...
Philip L. Reno   +4 more
wiley   +1 more source

A head start: The relationship of placental factors to craniofacial and brain development

open access: yesDevelopmental Dynamics, EarlyView.
Abstract In recent years, the importance of placental function for fetal neurodevelopment has become increasingly studied. This field, known as neuroplacentology, has greatly expanded possible etiologies of neurodevelopmental disorders by exploring the influence of placental function on brain development.
Annemarie Jenna Carver   +2 more
wiley   +1 more source

Ontogeny of RSPO1, FOXL2, and RUNX1 during ovarian differentiation in the marsupial tammar wallaby

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background RSPO1 and FOXL2 are female sex‐determining genes involved in the differentiation and organization of the ovary in some eutherian mammals. Mutations or loss of function of these genes are associated with partial to full sex reversal in mice, humans, and goats.
Monika R. Paranjpe   +3 more
wiley   +1 more source

Molecular anatomy of emerging Xenopus left–right organizer at successive developmental stages

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Vertebrate left–right symmetry breaking is preceded by formation of left–right organizer. In Amphibian, this structure is formed by gastrocoel roof plate, which emerges from superficial suprablastoporal cells. GRP is subdivided into medial area, which generates leftward flow by rotating monocilia and lateral Nodal1 expressing areas,
Natalia Petri   +3 more
wiley   +1 more source

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