Results 131 to 140 of about 115,546 (340)

Using an Instrumental Variable to Test for Unmeasured Confounding [PDF]

open access: yesStatistics in Medicine 2014, Volume 33, Issue 20, Pages 3528-3546, 2016
An important concern in an observational study is whether or not there is unmeasured confounding, i.e., unmeasured ways in which the treatment and control groups differ before treatment that affect the outcome. We develop a test of whether there is unmeasured confounding when an instrumental variable (IV) is available.
arxiv  

Gene Therapy Using Recombinant AAV Type 8 Vector Encoding TNAP‐D10 Improves the Skeletal Phenotypes in Murine Models of Osteomalacia

open access: yesJBMR Plus, Volume 7, Issue 1, January 2023., 2023
ABSTRACT Hypophosphatasia (HPP), caused by loss‐of‐function mutations in the ALPL gene encoding tissue‐nonspecific alkaline phosphatase (TNAP), is characterized by skeletal and dental hypomineralization that can vary in severity from life‐threatening to milder manifestations only in adulthood.
Flavia Amadeu de Oliveira   +7 more
wiley   +1 more source

Bayesian Inference of Individualized Treatment Effects using Multi-task Gaussian Processes [PDF]

open access: yesarXiv, 2017
Predicated on the increasing abundance of electronic health records, we investi- gate the problem of inferring individualized treatment effects using observational data. Stemming from the potential outcomes model, we propose a novel multi- task learning framework in which factual and counterfactual outcomes are mod- eled as the outputs of a function in
arxiv  

Premature Infant Gut Microbiome relationships with childhood behavioral scales: preliminary insights. [PDF]

open access: yesFront Nutr, 2023
Ozorio Dutra SV   +4 more
europepmc   +1 more source

Built‐In Electric Field Effects Tailoring Solvation Sheath and Desolvation Processes of Solvated Zn2+ Toward Stable Aqueous Rocking‐Chair Zinc‐Ion Batteries

open access: yesCarbon Energy, EarlyView.
TiO2/TiSe2–C heterointerfaces can create built‐in electric fields (BEFs) effects, and the intercalation mechanism is converted from the of Zn(H2O)62+ to smaller Zn(H2O)22+, featuring lower charge transfer energy barriers, faster ion transfer kinetics, suppression of HER, increased Ti–Se bond strength, and enhanced structural stabilities.
Peng Cai   +9 more
wiley   +1 more source

“Ears of the Lynx” Sign on Brain MRI in Siblings With Spastic Paraplegia: A Case Report

open access: yesAnnals of the Child Neurology Society, EarlyView.
ABSTRACT Background Hereditary spastic paraplegia (HSP) is a rare, clinically and genetically heterogenous condition that selectively affects the terminal segment of the descending corticospinal tract of the lumbar spine area, causing lower extremity spastic weakness with or without associated complex neurological symptoms.
Qingqing Wang, Manikum Moodley
wiley   +1 more source

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