Results 271 to 280 of about 1,241,202 (345)

First Report of Homozygous COL7A1 c.5756delG Mutation Causing Recessive Dystrophic Epidermolysis Bullosa in a Non‐Consanguineous Japanese Family

JEADV Clinical Practice, EarlyView.
ABSTRACT Severe recessive dystrophic epidermolysis bullosa (RDEB) is usually caused by biallelic loss‐of‐function mutations in COL7A1. While the c.5756delG variant has been previously reported in heterozygous form, its clinical impact in homozygosity has not been described.
Nozomi Kohama, Sayaka Yamaguchi, Teruki Yanagi, Yumi Akamine, Kimiko Nonaka, Daisuke Utsumi, Kenzo Takahashi   +6 more
wiley   +1 more source

Acid Suppression in Mild‐Moderate Laryngomalacia Without GERD: A Randomized Controlled Trial

The Laryngoscope, EarlyView.
Infants ≤ 6 months old with mild to moderate laryngomalacia at a tertiary children's hospital were randomized to famotidine and feeding modifications (AST) or feeding modifications alone (no‐AST). Patients randomized to AST (n = 20) and no‐AST (n = 20) had comparable improvement on Laryngomalacia Airway Symptom Score and Infant Gastroesophageal Reflux ...
Amber D. Shaffer, Zainab Balogun, Allison B. J. Tobey, Raymond C. Maguire, Jeffrey P. Simons, Joseph E. Dohar, Jennifer L. Mccoy, Marina V. Rushchak, Reema Padia   +8 more
wiley   +1 more source

A Learning Health System Approach to Developing a Perinatal Safety Framework and Guide to Reduce Disparities in Maternal Harm

Learning Health Systems, EarlyView.
ABSTRACT Introduction Maternal harm disproportionately affects Black birthing individuals, with systemic and provider‐related factors contributing significantly to preventable severe maternal morbidity (SMM) and maternal mortality. Despite the severity of the crisis, traditional maternal safety approaches, which typically exclude patient voices ...
Angela D. Thomas, Tamika Auguste, Allan Fong, Aaron Z. Hettinger, Seth Krevat, Laura Lee, Emily Mutondo, Deborah F. Perry, Karey Sutton, Saanvi Garg, Loral Patchen   +10 more
wiley   +1 more source

The Management of Parkinson's Disease Before, during and after Pregnancy—an MDS Scientific Issues Committee Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Pregnancy after a Parkinson's diagnosis presents complex challenges. Due to the paucity of literature, there is no evidence‐based guidelines and protocols for preconception care, management of pregnancy, childbirth and the postpartum period in women with early‐onset Parkinson's disease (PD).
Alexander C. Lehn, Jee‐Young Lee, Giorgia Sciacca, Stacy Patterson, Adam Morton, Paul Pun, Walaa A. Kamel, Marina Picillo, Bart Post, Eng‐King Tan, Tamine Capato, Bastiaan R. Bloem, Manon Auffret, Annelien M. Oosterbaan, Willanka Kapelle, Michiko K. Bruno, Lorraine V. Kalia, Jeffrey H. Kordower, Daniela Berg   +18 more
wiley   +1 more source

A pilot study of fecal pH and redox as functional markers in the premature infant gut microbiome. [PDF]

PLoS One
Letourneau J, Walker L, Han SH, David LA, Younge N.   +4 more
europepmc   +1 more source

Human Cyclophilins—An Emerging Class of Drug Targets

Medicinal Research Reviews, EarlyView.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova, Hana Navratilova, Kamil Musilek, Ondrej Benek   +3 more
wiley   +1 more source

Combination Therapy for OXA-48 Carbapenemase-Producing Klebsiella Pneumoniae Bloodstream Infections in Premature Infant: A Case Report and Literature Review. [PDF]

Infect Drug Resist
Chen Y, Fang C, Luo J, Pan X, Gao Z, Tang S, Li M.   +6 more
europepmc   +1 more source

Respiratory Syncytial Virus (RSV): A Comprehensive Overview From Basic Biology to Clinical Prevention and Control

Medicinal Research Reviews, EarlyView.
ABSTRACT Respiratory syncytial virus (RSV) is a common virus that causes respiratory infections, posing a serious threat, particularly to infants, the elderly, and individuals with compromised immune systems. As the leading cause of lower respiratory tract infections (LRTIs) in infants, RSV is responsible for millions of cases worldwide each year.
Jie Shi, Xiya Huang, Chunjun Ye, Yishan Lu, Yanyan Liu, Yuquan Wei, Xiawei Wei   +6 more
wiley   +1 more source

Characterizing Perinatal Treatment Patterns and Outcomes in Myasthenia Gravis

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Studies on pregnancy in myasthenia gravis (MG) are limited by small sample sizes or examine a limited number of outcomes. The objective of this study was to estimate the prevalence of perinatal and infant outcomes and characterize perinatal treatment patterns in MG.
Melanie H. Jacobson, Rupa Makadia, Ashley E. L. Anderson, Zia Choudhry, Nathan Hall, Jill Hardin, Sicong Huang, Janice M. Massey, Anna Ostropolets, Ran Sun, Rebecca Zaha, Alexis A. Krumme   +11 more
wiley   +1 more source

Transferring an extremely premature infant to an extra-uterine life support system: a prospective view on the obstetric procedure. [PDF]

Front Pediatr
van Haren JS, Delbressine FLM, Schoberer M, Te Pas AB, van Laar JOEH, Oei SG, van der Hout-van der Jagt MB.   +6 more
europepmc   +1 more source