Results 281 to 290 of about 254,139 (337)

A pilot study of fecal pH and redox as functional markers in the premature infant gut microbiome. [PDF]

PLoS One
Letourneau J, Walker L, Han SH, David LA, Younge N.   +4 more
europepmc   +1 more source

Diagnosis and Management of Prenatal Hereditary Pyropoikilocytosis

Prenatal Diagnosis, EarlyView.
ABSTRACT Hereditary pyropoikilocytosis (HPP) is a severe hemolytic anemia caused by variants in SPTA1, SPTB, and EPB41. These weaken horizontal interactions in the erythrocyte cytoskeleton, causing membrane fragmentation and splenic sequestration. It will readily cause fetal anemia and often hydrops fetalis. Prenatal diagnosis requires first ruling out
Connor Hartzell, Samantha Stover, Nora Gibson, Timothy Olson, James Connelly, Matthew Grace, Jennifer Andrews   +6 more
wiley   +1 more source

The Expanding Role of Gene Sequencing in Shaping Fetal Therapies: Clinical and Ethical Considerations

Prenatal Diagnosis, EarlyView.
ABSTRACT In utero interventions are transformative in addressing genetic and anatomic conditions during fetal development. Next generation sequencing enables early genetic testing, playing a pivotal role in prenatal decision‐making by supporting risk stratification, precise and timely diagnosis, which directly informs eligibility for fetal surgical and
Matthew A. Shear, Beltran Borges, Billie R. Lianoglou, Tony Lum, Emma Canepa, Jennifer L. Cohen, Julia E. H. Brown, Akos Herzeg   +7 more
wiley   +1 more source

Hemolytic Disease of the Fetus and Newborn: Fetal RHD Genotyping, Targeted Prophylaxis, and Prenatal Therapies

Prenatal Diagnosis, EarlyView.
ABSTRACT Hemolytic disease of the fetus and newborn (HDFN) remains a significant concern in prenatal care primarily caused by maternal alloimmunization against fetal red blood cell antigens, most commonly the D antigen. Noninvasive fetal RHD genotyping, used as a screening tool, enables targeted antenatal prophylaxis and has been implemented in several
Emilie Thorup, Steffen Thorsen, Morten Hanefeld Dziegiel, Olav Bjørn Petersen, Frederik Banch Clausen   +4 more
wiley   +1 more source

Combination Therapy for OXA-48 Carbapenemase-Producing Klebsiella Pneumoniae Bloodstream Infections in Premature Infant: A Case Report and Literature Review. [PDF]

Infect Drug Resist
Chen Y, Fang C, Luo J, Pan X, Gao Z, Tang S, Li M.   +6 more
europepmc   +1 more source

Clinical characteristics and risk factors of severe bocavirus‐positive pneumonia in children and a literature review

Pediatric Discovery, EarlyView.
The study explored the clinical characteristics and risk factors of HBoV‐positive severe pneumonia in children. These findings indicate that HBoV can be identified in respiratory samples from children with severe pneumonia, denoting its role as a viral pathogen in hospitalized children with this condition.
Jing Liao, Zhongying Yang, Yu He, Jianhua Wei, Luo Ren, Enmei Liu, Na Zang   +6 more
wiley   +1 more source

Development and Validation of a Nurse‐Led Developmental Intervention Package to Improve the Neurodevelopmental Outcomes of Preterm Babies in Neonatal Intensive Care Unit

Pediatric Discovery, EarlyView.
ABSTRACT Preterm birth is a major global health concern associated with high morbidity and mortality rates, along with long‐term neurodevelopmental impairments. Developmental supportive care (DSC) plays a crucial role in optimizing neurodevelopmental outcomes in these vulnerable neonates.
V. A. Raghu, Manju Vatsa, Neeraj Gupta, Hansraj, Ramesh Choudhary   +4 more
wiley   +1 more source

Transferring an extremely premature infant to an extra-uterine life support system: a prospective view on the obstetric procedure. [PDF]

Front Pediatr
van Haren JS, Delbressine FLM, Schoberer M, Te Pas AB, van Laar JOEH, Oei SG, van der Hout-van der Jagt MB.   +6 more
europepmc   +1 more source

Succinate Promotes M1 Polarization of Intestinal Macrophages in Mice With Necrotizing Enterocolitis Through the PI3K/AKT Pathway

Pediatric Discovery, EarlyView.
Succinate promotes macrophage to the M1 phenotype in the mouse mononuclear macrophage leukemia cells (Raw264.7 cells) and neonatal mice with NEC. Succinate activates the phosphatidylinositol 3‐kinase/protein kinase B (PI3K/AKT) pathway via succinate recepter 1 (SUCNR1), promoting M1 polarization of NEC intestinal macrophages.
Sha Liu, Fang‐Ling Tang, Xiao‐Lin Yan, Xiao‐Chen Liu, Qing Ai, Lu‐Quan Li, Lei Bao   +6 more
wiley   +1 more source

From skin to syndrome: The progression of primary cutaneous aspergillosis to extremity compartment syndrome in a premature infant. Case report and review of the literature. [PDF]

Int J Surg Case Rep
Ramos-Irizarry C.
europepmc   +1 more source