Results 121 to 130 of about 253,780 (335)

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons   +17 more
wiley   +1 more source

Observations related to chronologic and gynecologic age in pregnant adolescents. [PDF]

open access: yes, 1984
A low chronologic age (less than or equal to 15 years) and low gynecologic age (less than or equal to 2 years) have been considered factors that increase medical complications among adolescent pregnant women. Gynecologic age (GA) is defined in this study
Felice, ME   +3 more
core  

Toward a working definition of ketogenic diet resistance in GLUT1 deficiency syndrome

open access: yesEpileptic Disorders, EarlyView.
Abstract Objective The ketogenic diet (KD) is the standard treatment for glucose transporter type 1 deficiency syndrome (GLUT1‐DS), typically yielding seizure reduction and cognitive/motor gains. However, a small subset of patients shows limited or no clinical benefit.
Raffaele Falsaperla   +8 more
wiley   +1 more source

Unmet needs of women with epilepsy living in rural low‐ and middle‐income countries: The experience of the Bolivian Chaco

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Epilepsy affects approximately 70 million people worldwide, with 80% living in low‐ and middle‐income countries (LMICs), where many people with epilepsy (PWE) go undiagnosed or untreated. Over the last few decades, many efforts have been made worldwide to reduce the treatment gap (TG) in LMICs.
Alessandra Nicoletti   +13 more
wiley   +1 more source

A Review of the Principles and Benefits of Cue-Based Feeding [PDF]

open access: yes, 2015
Literature reflects that neonatal clinical practices are increasingly infant-driven, and promote, developmentally based care. Particularly, in the area of oral feeding, practitioners are moving away from traditional gestational age criteria for the ...
Cormier, Diana M
core   +1 more source

Epilepsy syndromes classification

open access: yesEpilepsia Open, EarlyView.
Abstract Epilepsy syndromes are distinct electroclinical entities which have been recently defined by the International League Against Epilepsy Nosology and Definitions Task Force. Each syndrome is associated with “a characteristic cluster of clinical and EEG features, often supported by specific etiologic findings”.
Elaine C. Wirrell   +4 more
wiley   +1 more source

Genetic epilepsies with myoclonic seizures: Mechanisms and syndromes

open access: yesEpilepsia Open, EarlyView.
Abstract Genetic epilepsy with myoclonic seizures encompasses a heterogeneous spectrum of conditions, ranging from benign and self‐limiting forms to severe, progressive disorders. While their causes are diverse, a significant proportion stems from genetic abnormalities.
Antonietta Coppola   +3 more
wiley   +1 more source

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