Results 281 to 290 of about 253,780 (335)

Succinate Promotes M1 Polarization of Intestinal Macrophages in Mice With Necrotizing Enterocolitis Through the PI3K/AKT Pathway

Pediatric Discovery, EarlyView.
Succinate promotes macrophage to the M1 phenotype in the mouse mononuclear macrophage leukemia cells (Raw264.7 cells) and neonatal mice with NEC. Succinate activates the phosphatidylinositol 3‐kinase/protein kinase B (PI3K/AKT) pathway via succinate recepter 1 (SUCNR1), promoting M1 polarization of NEC intestinal macrophages.
Sha Liu, Fang‐Ling Tang, Xiao‐Lin Yan, Xiao‐Chen Liu, Qing Ai, Lu‐Quan Li, Lei Bao   +6 more
wiley   +1 more source

Nurses' perspectives on implementing sleep protection for premature infants in the neonatal intensive care unit: a qualitative study. [PDF]

BMC Health Serv Res
Gu Y, Tang Y, Xue Y, Wu J, Xie J.
europepmc   +1 more source

Docosahexaenoic acid ameliorates autistic‐like behaviors by inhibiting oxidative stress and inflammatory response in neonatal maternal separation rats

Pediatric Discovery, EarlyView.
The JNK pathway and oxidative stress are activated, and pro‐inflammatory cytokines are increased in neonatal maternal separation (NMS) rats. While docosahexaenoic acid treatment suppresses the activation of JNK pathway and oxidative stress, and reduces pro‐inflammatory cytokines release, thereby improving autism‐like behavior induced by NMS.
Boqing Xu, Hao Yuan, Xiaohuan Li, Qingyang Yu, Chunfang Dai, Zhifang Dong   +5 more
wiley   +1 more source

Short-Term Effects over Time of Endotracheal Suctioning on Very Low Birth Weight Premature Infants with RDS. [PDF]

Children (Basel)
Virsilas E, Valiulis A, Liubsys A.
europepmc   +1 more source

A 15‐year population‐based study on incidence and vaccination coverage in pediatric inflammatory bowel disease in Italy

Pediatric Investigation, EarlyView.
Increasing incidence of pediatric inflammatory bowel disease (IBD) and suboptimal vaccination coverage in Apulia, Italy (2009–2023). A total of 1044 incident cases of paediatric IBD were identified in the period 2009–2023 in Apulia, Italy, giving an average annual standardized incidence rate of 12.7/100 000. A significant increase in incidence occurred
Francesca Fortunato, Angelo Campanozzi, Michele Di Toma, Alessandra Marinari, Domenico Martinelli   +4 more
wiley   +1 more source

Predictive value of transcranial Doppler ultrasound for brain development and craniocerebral injury in premature infants. [PDF]

Am J Transl Res
Lu Q, Lu YJ, Chen ZH, Cao CY, Wu W.
europepmc   +1 more source

Comparison of Model‐Predicted and Observed Evinacumab Pharmacokinetics and Efficacy in Children Aged < 5 Years With Homozygous Familial Hypercholesterolemia

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Evinacumab, an angiopoietin‐like 3 inhibitor, significantly reduces low‐density lipoprotein cholesterol (LDL‐C) in patients with homozygous familial hypercholesterolemia (HoFH). Herein, we report pharmacokinetic and efficacy analyses of evinacumab in < 5‐year‐old patients with HoFH.
Sébastien Bihorel, Robert Dingman, Jeanne Mendell, Katy C. Norman, Richard T. George, Xue‐Qiao Zhao, Robert Pordy, Daniel Garcia, Wendy S. Putnam, Geetha Raghuveer, Brian W. McCrindle, Elena Fornari, Ivo Baric, Shubha Srinivasan, Melissa Diamond, Eliot A. Brinton, John D. Davis, A. Thomas DiCioccio, Lutz Harnisch   +18 more
wiley   +1 more source

Onasemnogene-abeparvovec administration to premature infants with spinal muscular atrophy. [PDF]

Ann Clin Transl Neurol
Brown SM, Ajjarapu AS, Ramachandra D, Blasco-Pérez L, Costa-Roger M, Tizzano EF, Sumner CJ, Mathews KD.   +7 more
europepmc   +1 more source

White noise's effect on premature infants' physiological parameters during peripheral intravenous catheter insertion. [PDF]

BMC Pediatr
Rahimi O, Roshan FS, Nikrouz L.
europepmc   +1 more source

Reducing Iatrogenic Blood Losses in Premature Infants. [PDF]

Pediatrics
Sharma M, Bowman E, Zheng F, Spencer HJ, Shukri SA, Gates K, Williams M, Peeples S, Hall RW, Schootman M, Landes SJ, Curran GM.   +11 more
europepmc   +1 more source