Results 161 to 170 of about 452,856 (295)

Fhod3 in zebrafish supports myofibril stability during growth of embryonic skeletal muscle

Developmental Dynamics, EarlyView.
Abstract Background Actin filament organization in cardiomyocytes critically depends on the formin Fhod3, but a role for Fhod3 in skeletal muscle development has not yet been described. Results We demonstrate here that in zebrafish mutated for one of two fhod3 paralog genes, fhod3a, skeletal muscle of the trunk appears normal through 2 days post ...
Aubrie Russell, Tracy Eng, Jeffrey D. Amack, David Pruyne   +3 more
wiley   +1 more source

Co‐Producing the Transition to Eating Disorder Youth Intervention: Experience‐Based Co‐Design Workshops Supporting Young People in Transition

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Eating disorders (EDs) are severe and complex psychiatric illnesses, with adolescence and young adulthood representing particularly vulnerable periods for onset, relapse and disruptions in treatment. The transition from Child and Adolescent Mental Health Services (CAMHS) to Adult Mental Health Services (AMHS) is especially complex ...
Maria Livanou, Marta Marlais, Charlotte Burton, Nora Kornai, Anna Bromley, Pareena Dutt, Jiarui Li, Tiffany Luxford, Francesca Marshall, Maria Georgia Dioletta, Molly Henson, Jun Teh, Emily Nuttall, Ashish Kumar, Kevin Christian, Carolyn Hatton, Zara Smalley, Grace Hill, Anya Heneghan, Kat Novogrudsky   +19 more
wiley   +1 more source

Learning the Lessons of Premature Discontinuation of Eating Disorder Therapy: Informing Guidelines to Improve Retention

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Around one to two in five patients prematurely disengage from eating disorder therapy. This Forum paper suggests innovative strategies to increase retention and strategies for evaluating these with patients who have eating disorders.
Tracey D. Wade, Ulrike Schmidt
wiley   +1 more source

Air Pollution, COVID-19-related Air-quality Changes, and Premature Mortality in Türkiye (2019-2023). [PDF]

Thorac Res Pract
Han Yekdeş D, Yekdeş AC.
europepmc   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Unfavorable Social Determinants of Health and Obesity: A Double Jeopardy for Premature Mortality. [PDF]

JACC Adv
Philip J, Hagan K, Shahid I, Chang R, Prakash S, Friedman M, Titus A, Kundi H, Amin Z, Javed U, Avenatti E, Al-Kindi S, Nasir K, Javed Z.   +13 more
europepmc   +1 more source

Gut microbiota‐related modulation of immune mechanisms in post‐infarction remodelling and heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 942-954, April 2025.
Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler, Friederike Zimmermann, Bettina Heidecker, Ulf Landmesser, Arash Haghikia   +4 more
wiley   +1 more source

Vitamin D, premature mortality, and life expectancy among US adults. [PDF]

Arch Public Health
Wang Q, Li C, Ma N, Zheng F, Wang B, Lin Q, Dong X, Niu W.   +7 more
europepmc   +1 more source

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source

Premature mortality from respiratory disease attributable to PM_2.5 exposure in Lanzhou, Gansu Province, China. [PDF]

Int J Occup Med Environ Health
Aiken Y, Wang L, Liu X.
europepmc   +1 more source