Results 101 to 110 of about 16,137 (234)

TMEM16A chloride channels in the female reproductive tract and their role in normal and dysfunctional pregnancy and labour

The Journal of Physiology, EarlyView.
Abstract figure legend TMEM16A plays a pivotal role in setting the duration of the action potential plateau in human uterine smooth muscle. An increase in TMEM16A expression in labour underpins a lengthening of the plateau and this provides time for the contraction to become larger and longer, important for timely successful labour.
Helena C. Parkington, Harold A. Coleman, Penelope M. Sheehan, Shaun P. Brennecke, Marianne Tare   +4 more
wiley   +1 more source

Glucocorticoids modulate drug transporter function in human fetal brain endothelial cells

The Journal of Physiology, EarlyView.
Abstract figure legend P‐glycoprotein and breast cancer resistance protein are the most prominent drug transporters at the fetal blood–brain barrier. We isolated primary human fetal brain endothelial cells from early and mid‐gestation cerebral microvessels and exposed them to glucocorticoids cortisol and dexamethasone in vitro.
Nikola Ivanovski, Phetcharawan Lye, Enrrico Bloise, Stephen G. Matthews   +3 more
wiley   +1 more source

Psychotropic medication and the fetal brain

The Journal of Physiology, EarlyView.
Abstract figure legend Brain region changes linked to in‐utero psychotropic exposure. Abstract Medications known to cross the blood–brain barrier (psychotropic medications) are commonly prescribed to women during pregnancy, often for the management of mental illness.
Oliver Gale‐Grant, Tomoki Arichi
wiley   +1 more source

Impact of gestational weight gain on perineal injury and obstetric anal sphincter injury among underweight primiparous women

International Journal of Gynecology &Obstetrics, Volume 174, Issue 1, Page 106-113, July 2026.
Abstract Objective To evaluate the association between gestational weight gain (GWG) and perineal trauma in primiparous women with a pre‐pregnancy body mass index (BMI) <18.5. Methods This retrospective cohort study included primiparous women with singleton, vertex deliveries at a tertiary medical center (2012–2023).
Itamar Gilboa, Daniel Gabbai, Emmanuel Attali, Ronen Gold, Asnat Groutz, Yariv Yogev, Yoav Baruch   +6 more
wiley   +1 more source

Trends and determinants of acute tocolysis implementation in Japan, 2012-2023: An 11-year nationwide retrospective cohort study. [PDF]

PLoS One
Toba M, Oi R, Moriwaki M, Kakehashi M, Fudono A, Fushimi K, Miyasaka N.   +6 more
europepmc   +1 more source

Therapeutic role of nifedipine in threatened preterm labor: Current evidence and future perspectives

International Journal of Gynecology &Obstetrics, Volume 174, Issue 1, Page 70-78, July 2026.
Abstract Preterm birth occurs in approximately 10% of all pregnancies, and is not only the leading cause of neonatal mortality but also a major contributor to short‐ and long‐term morbidities due to immaturity. Preterm birth has also been linked to an increased risk of maternal cardiovascular and cerebrovascular diseases, making it a critical concern ...
Hikaru Imatake, Yoshitsugu Chigusa, Haruta Mogami, Satoshi Morita, Masaki Mandai   +4 more
wiley   +1 more source

Obstetric and Neonatal Outcomes Following Immediate Delivery Versus Expectant Management in Pregnant Women With Preterm Premature Rupture of Membranes During the Late Preterm Period in Korea. [PDF]

J Korean Med Sci
Kwon H, Kwon JY, Kang S, Ko HS, Kwon HS, Oh KJ, Oh SY, Lee MY, Choi SR, Han YJ, Sul AR, Jung Y, Kim J, Park JJ, Lee J, Kim YN, Yang JI.   +16 more
europepmc   +1 more source

Cesarean delivery on maternal request and Robson classification

International Journal of Gynecology &Obstetrics, Volume 174, Issue 1, Page 347-352, July 2026.
Abstract Objective To describe the types of cesarean delivery on maternal request (CDMR), and to analyze the distribution of delivering types according to the Robson Classification (RC) and the distribution of comorbidities among the different groups of delivering types. Methods Cross‐sectional study using electronic records of deliveries that occurred
Cristine Moreira Silva Benetti, Célia José Laice Sitoe Muhandule, Laura Bianchini Fogulin, Helymar Da Costa Machado, Eliana Amaral   +4 more
wiley   +1 more source

The role of large language models in the diagnosis and management of obstetric patients: a pilot feasibility study using simulated obstetric cases. [PDF]

Arch Gynecol Obstet
Psilopatis I, Redling K, Filippi V, Kappos S, Emons J, Mosimann B, Zwimpfer TA.   +6 more
europepmc   +1 more source

Maternal risk factors for postpartum readmission following vacuum‐assisted vaginal delivery: A retrospective cohort study

International Journal of Gynecology &Obstetrics, Volume 174, Issue 1, Page 416-423, July 2026.
Abstract Objective To identify risk factors associated with postpartum readmission following vacuum‐assisted vaginal delivery. Methods A retrospective cohort study at a single university‐affiliated tertiary medical center from 2012 to 2023, including all singleton pregnancies delivered at ≥37 weeks' gestation.
Itamar Gilboa, Keren‐Or Wertheimer, Daniel Gabbai, Emmanuel Attali, Yariv Yogev, Anat Lavie   +5 more
wiley   +1 more source