Results 121 to 130 of about 763 (215)
Incidence and preventability of severe early pregnancy morbidity at a tertiary referral center
Abstract Objectives To identify the incidence of severe early pregnancy morbidity (SEPM) by adapting severe maternal morbidity (SMM) definitions to pregnancies <24 weeks; secondarily, to assess preventability of these events using a validated tool Methods This is a retrospective cohort study of pregnant patients at a single tertiary care institution ...
Susan E. Nourse +7 more
wiley +1 more source
Decoding neurodevelopment risks of exposures to intoxication, infection, and trauma during pregnancy
Abstract The maternal environment plays a pivotal role in fetal neurodevelopment, but adverse conditions during pregnancy may disrupt key developmental processes. Conditions such as intoxication, infection, or trauma during pregnancy have been associated with impaired fetal oxygenation, altered immune signaling, and disrupted placental function, which ...
Brenda E. Lujan +7 more
wiley +1 more source
DHCR24 Alleviates DNA Damage in Senescent Vascular Endothelial Cells via ENKUR/Ca2+ Signaling
In senescent vascular endothelial cells, DHCR24 deficiency triggers ENKUR‐dependent Ca2+ overload, which in turn induces endoplasmic reticulum stress and mitochondrial dysfunction, ultimately exacerbating oxidative stress and DNA damage. ABSTRACT DNA damage is considered one of the major contributors to aging.
Han Li +11 more
wiley +1 more source
Women with one previous cesarean section and spontaneous labor had the most favorable outcomes in this high‐fertility, resource‐limited setting. Reducing unnecessary elective repeat cesarean section , together with careful decisions regarding primary cesarean section, is not only about lowering cesarean rates but about minimizing cumulative maternal ...
Raffaela Baiocchi +16 more
wiley +1 more source
Home telemonitoring in high‐risk pregnancies: A Finnish retrospective cohort study
This retrospective study suggests that home telemonitoring may provide an acceptable approach for managing selected high‐risk pregnancies. Safe and effective implementation requires careful patient selection and adherence to evidence‐based clinical protocols.
Tiina Stark, Heidi Kruit, Leena Rahkonen
wiley +1 more source
Women with a twin pregnancy who undergo induction of labor or elective cesarean section at term are comparable for blood loss but with higher admissions to the neonatal unit. Abstract Introduction Our aim was to assess maternal and perinatal morbidity associated with induction of labor (IOL) and elective cesarean section (ECS) in uncomplicated twin ...
Joanna Gent +5 more
wiley +1 more source
Transmasculine pregnancy—Occurrence, associations, and outcomes: A quantitative systematic review
This quantitative systematic review of 44 studies shows that a significant minority of transmasculine people become pregnant, including after transition. Miscarriage and postnatal depression rates appeared high, but there was minimal information on most other important outcomes, demonstrating that more research is needed.
Catherine Meads +3 more
wiley +1 more source
ABSTRACT Aims and Methods Advances in neonatal care have extended borderline survival to 22–24 post‐conceptional weeks. Present review discusses approaches for prolonging short pregnancies and prevention of serious morbidities in extremely premature infants born before 28 weeks of pregnancy.
Mikko Hallman
wiley +1 more source
ABSTRACT Hyperglycaemia first diagnosed in pregnancy (HIP) is the most common medical condition affecting pregnancy, affecting up to 40% of pregnancies in some countries. The global incidence of HIP is increasing owing to rising rates of overweight and obesity, advanced maternal age, and early screening for HIP.
Emmanuel Cosson +2 more
wiley +1 more source
This study investigated the effects of clinically relevant concentrations of doxorubicin (Dox; 5 μM), commonly used in anticancer therapy, on adipose‐derived stem cells (ADSCs). Dox induced ADSC dysfunction, characterized by reduced mitochondrial activity, apoptosis, oxidative stress, premature senescence, cytoskeletal alterations, and cell cycle ...
Aleksandra Skubis‐Sikora +5 more
wiley +1 more source

