Results 91 to 100 of about 32,460 (262)

A rhesus macaque model of α‐dystroglycanopathy caused by a POMT1 splice altering variant

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Rhesus macaques homozygous for a naturally occurring spice altering variant in the POMT1 gene develop lissencephaly, microphthalmia, and muscular contracture. The presentation models severe presentation of the human Walker‐Warburg syndrome. Abstract Background Biallelic mutations in genes associated with α‐dystroglycan glycosylation manifest in a ...
Anya Nordlund   +7 more
wiley   +1 more source

Premature rupture of preterm membranes and their relationship with maternal and perinatal consequences

open access: yesActa Médica del Centro, 2016
Introduction: premature rupture of membranes is considered as a solution of continuity of ovular membranes before the onset of labor. Objective: to analyze maternal and perinatal consequences of rupture of preterm membranes.
Juan Antonio Suárez González   +3 more
doaj  

Role of altered amniotic fluid cytokine profile in in development of fetal membrane insufficiency

open access: yesМедицинская иммунология
Studies on pathogenesis of fetal membrane insufficiency in preterm pregnancy should expand the opportunities of predicting prenatal rupture of amniotic fluid and improve the strategy of anticipant gestation management in cases of premature rupture of the
L. I. Dyatlova, T. N. Glukhova
doaj   +1 more source

Establishing Sensory Neurons as Therapeutic Targets in Peripheral Neuropathy Driven by Polyglutamine Expanded Murine ATXN3

open access: yesAnnals of Neurology, EarlyView.
Repeat expansion disorders frequently involve peripheral neuropathy, yet mechanisms remain unclear. Using a spinocerebellar ataxia type 3 (SCA3) Knock‐In Atxn3Q300/Q6, we identify progressive sensorimotor deficits, peripheral nerve pathology, and dorsal root ganglia RNA splicing dysregulation.
Juan P. Mato   +7 more
wiley   +1 more source

Preterm and premature rupture of fetal membranes

open access: yesGinekologia Polska
Premature rupture of fetal membranes (PRFM) is rupture of fetal membranes before onset of labor (pre-labor) and after 37 gestational weeks. Preterm premature rupture of fetal membranes (PPRFM) is rupture of fetal membranes before 37 gestational weeks ...
Svetlana Shikanova   +3 more
doaj   +1 more source

Proto‐Panic Modulation by Caffeine‐Proteinoid Complexes

open access: yesJournal of Applied Polymer Science, EarlyView.
Caffeine–proteinoid microspheres synthesized by thermal polymerization exhibit compartmentalized drug loading with encapsulation efficiencies of 61%–82% and triphasic release kinetics. Electrochemical monitoring reveals multi‐scale oscillatory dynamics consistent with chaotic and damped harmonic behavior, while Boolean logic operations demonstrate ...
Panagiotis Mougkogiannis   +1 more
wiley   +1 more source

Eudragit®‐engineered pH‐responsive probiotic microspheres with enhanced gastrointestinal resistance and prolonged storage stability for inflammatory bowel disease therapy

open access: yesBMEMat, EarlyView.
This study reports the development of AMS@Eud core‐shell microspheres, combining calcium alginate and pH‐responsive Eudragit® L100, which exhibit exceptional gastrointestinal resistance and long‐term storage stability (only 5.28%–9.09% viability loss over 35 days at 4–25°C), and effectively alleviate inflammatory bowel disease via gut microbiota ...
Ming Teng   +5 more
wiley   +1 more source

Harnessing blood clot as a native scaffold for orchestrating tissue repairs and regeneration

open access: yesBMEMat, EarlyView.
The blood clot, owing to its dynamic composition and unique microenvironment, holds significant yet underappreciated potential for tissue engineering. This review systematically summarizes the pathophysiology of clot formation, the key regulatory factors shaping its microenvironment, and its applications in both pre‐clinical and clinical settings ...
Gao‐peng Dang   +13 more
wiley   +1 more source

Premature rupture of membranes.

open access: yesCanadian family physician Medecin de famille canadien, 2012
The management of premature rupture of the amniotic membranes before 37 weeks gestation remains controversial. The authors of this article outline the risks involved for the fetus, define the various terms related, and discuss the antepartum and intrapartum management of such an event and offer a protocol that they have developed.
A, Akierman, S, Iwanicki
openaire   +1 more source

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