Results 131 to 140 of about 32,053 (264)

Aberrant alternative splicing of purinergic receptor P2RX4 prevents sensitivity towards combinatorial treatment in colorectal and pancreatic cancer

The Journal of Pathology, EarlyView.
Abstract Recently, we suggested the combination of chemotherapy and P2RX4 inhibition as a promising novel therapeutic approach for P2RX4‐expressing epithelial tumors to prevent paracrine resistance. Here, we aimed to assess whether determining P2RX4 expression status in colorectal and pancreatic cancer patients would allow stratification of potentially
Christoph Steup, Julian Dosch, Christopher Dietz‐Fricke, Sara Khosraviseftejani, Esther Engel, Adalbert F de Valk, Dominic Menger, Patrick Welker, Peter J Wild, Kilian B Kennel, Maja Kantlehner, Paul K Ziegler, Florian R Greten   +12 more
wiley   +1 more source

Does the Vaginal Microbiota Influence the Incidence of the Preterm Premature Rupture of Membranes? [PDF]

J Clin Med
Feduniw S, Zeber-Lubecka N, Pruc M, Gaca Z, Szarpak Ł, Ciebiera M.   +5 more
europepmc   +1 more source

Diagnosis and Management of Prenatal Hereditary Pyropoikilocytosis

Prenatal Diagnosis, EarlyView.
ABSTRACT Hereditary pyropoikilocytosis (HPP) is a severe hemolytic anemia caused by variants in SPTA1, SPTB, and EPB41. These weaken horizontal interactions in the erythrocyte cytoskeleton, causing membrane fragmentation and splenic sequestration. It will readily cause fetal anemia and often hydrops fetalis. Prenatal diagnosis requires first ruling out
Connor Hartzell, Samantha Stover, Nora Gibson, Timothy Olson, James Connelly, Matthew Grace, Jennifer Andrews   +6 more
wiley   +1 more source

Analysis of the Impact of Preterm Premature Rupture of Membranes (PPROM) on Maternal and Infant Outcomes and Countermeasures. [PDF]

Int J Womens Health
Chen Y, Zhou D, Tu Y, Wang Y.
europepmc   +1 more source

Hemolytic Disease of the Fetus and Newborn: Fetal RHD Genotyping, Targeted Prophylaxis, and Prenatal Therapies

Prenatal Diagnosis, EarlyView.
ABSTRACT Hemolytic disease of the fetus and newborn (HDFN) remains a significant concern in prenatal care primarily caused by maternal alloimmunization against fetal red blood cell antigens, most commonly the D antigen. Noninvasive fetal RHD genotyping, used as a screening tool, enables targeted antenatal prophylaxis and has been implemented in several
Emilie Thorup, Steffen Thorsen, Morten Hanefeld Dziegiel, Olav Bjørn Petersen, Frederik Banch Clausen   +4 more
wiley   +1 more source

Serum amyloid A as a diagnostic marker for histologic chorioamnionitis in preterm premature rupture of membranes: A diagnostic accuracy study. [PDF]

Int J Reprod Biomed
Faraji A, Mehraban M, Kasraeian M, Akbarzadeh-Jahromi M, Vafaei H, Asadi N, Oveisi Z, Kasraie M, Zare M.   +8 more
europepmc   +1 more source

Intrauterine Transfusions in Fetuses Affected by Parvovirus B19: Complications, Challenges and Outcomes

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective This study evaluates the procedural characteristics, complications, and outcomes of intrauterine transfusion (IUT) for fetal anemia caused by parvovirus B19 infection during the 2023–2024 epidemic in Northwestern Europe. Method This multicenter observational study included all fetuses undergoing IUT for proven parvovirus B19‐induced ...
Banu Özbakir, Emma Van den Eede, Lone N. Nørgaard, Roland Devlieger, Karin Sundberg, Monique C. Haak, Femke Slaghekke   +6 more
wiley   +1 more source

Longer leukocyte telomere length increases the odds of premature rupture of membranes: a cross-sectional study based on UK Biobank. [PDF]

Sci Rep
Xiao C, Su Y, Peng C, Li W, Chen Z, Long J, Shen Q, Ran Y, Wang Y, Hu J, Gao R.   +10 more
europepmc   +1 more source

Prenatal and Perinatal Outcomes in Fetuses With Macrocystic Congenital Pulmonary Airway Malformations: Thoracoamniotic Shunting Versus Expectant Management

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective Describe prenatal imaging characteristics, perinatal and postnatal outcomes in fetuses with isolated macrocystic congenital pulmonary airway malformations (CPAM) undergoing thoracoamniotic shunting (TAS) and expectant management. Methods Retrospective cohort study of 123 fetuses with isolated macrocystic CPAM managed at the Ontario ...
Laurence Sophie Carmant, Alexandria Kelly, SeungWoo Lee, Vesna Sokol Karadjole, Greg Ryan, Tim Van Mieghem, Prakesh S. Shah, Anna Otvodenko, Priscilla P. L. Chiu, Nimrah Abbasi   +9 more
wiley   +1 more source

The relationship of soluble urokinase plasminogen activator receptor levels with preterm premature rupture of membranes and predictive value in neonatal intensive care unit admission. [PDF]

Rev Assoc Med Bras (1992)
Koc BL, Tanacan A, Haliloglu E, Yilmaz HE, Ersak DT, Aktas BA, Kara O, Sahin D.   +7 more
europepmc   +1 more source