Results 281 to 290 of about 80,493 (383)

Cerebral Oxygenation During Transition and Amplitude‐Integrated Electroencephalography Signals: An Ancillary Study to the COSGOD‐III Trial

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim The COSGOD III trial was designed to guide oxygen delivery by cerebral near infrared spectroscopy (NIRS) in preterm neonates during the immediate transition after birth and showed a non‐significant increase of 4.3% in survival without cerebral injury compared to the control group.
Christina Schreiner   +9 more
wiley   +1 more source

“The Very Best That It Could Be and a Lot Better Than I Would Have Imagined”: Birthing People's Experiences of Transfer From Community to Hospital

open access: yesBirth, EarlyView.
ABSTRACT Background Community births (those in homes or freestanding birth centers) are increasing in the US, although they still represent a small percentage of total births. Research shows that community births can offer positive outcomes for low‐risk individuals, such as fewer interventions and greater satisfaction.
Carrie Neerland   +2 more
wiley   +1 more source

Influence of clinical risk factors for preterm premature rupture of membranes (PPROM) on the elastic strength of fetal membranes at term: A prospective study. [PDF]

open access: yesPLoS One
Robin A   +10 more
europepmc   +1 more source

The CRISPR‐Cas9 knockout DDC SH‐SY5Y in vitro model for AADC deficiency provides insight into the pathogenicity of R347Q and L353P variants: a cross‐sectional structural and functional analysis

open access: yesThe FEBS Journal, EarlyView.
Here, we generated a DDC‐KO cellular model for studying aromatic amino acid decarboxylase (AADC) deficiency. This model was created using CRISPR‐Cas9 in the SH‐SY5Y neuroblastoma cell line and was validated through the absence of the dopamine product and an altered l‐dopa metabolite profile.
Cristian Andres Carmona‐Carmona   +11 more
wiley   +1 more source

In vivo modeling of lethal congenital contracture syndrome 1 suggests pathomechanisms in cellular stress responses

open access: yesThe FEBS Journal, EarlyView.
Gle1 knockout mice fail to segregate cell lineages at the blastocyst stage, resulting in very early embryonic lethality. Gle1 knock‐in (KI) mice harboring a pathogenic variant giving rise to lethal congenital contracture syndrome 1 show both known and novel innervation defects, supportive of multiorgan pathology in human fetuses.
Tomáš Zárybnický   +22 more
wiley   +1 more source

High‐pressure freezing of mechanically stretched cells

open access: yesJournal of Microscopy, EarlyView.
Abstract High‐pressure freezing (HPF) is an electron microscopy (EM) preparation technique with superb ultrastructural preservation. Combined with EM tomography it provides virtual EM serial sections with extraordinary spatial resolution. For HPF, cells are usually cultured on a rigid sapphire disc that provides a tight fit in the holding bracket of ...
Edward Felder   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy